Increase in the apparent intercalation ability of a platinum complex via multivalency by installation into the sidechain of a graft copolymer and observation of structural changes in the intercalated DNA

Abstract

Pt complexes increase their apparent binding constant by grafting on sidechains of polymer segments via multivalent effect.

Accelerated Redox Reaction of Hydrogen Peroxide by Employing Locally Concentrated State of Copper Catalysts on Polymer Chain

“…First, the methacrylate monomer with DPA structure (DPAMA) was polymerized via reversible addition‐fragmentation chain transfer (RAFT) polymerization to prepare the metal–ligand pendent polymer (pDPAMA). [ 17 ] Briefly, DPAMA was synthesized by reacting 3‐aminopropan‐1‐ol with 2‐(chloromethyl)pyridine hydrochloride to obtain DPAOH, followed by a condensation reaction with methacryloyl chloride (Figure S1, Supporting Information). Then, pDPAMA was synthesized by the RAFT polymerization of DPAMA using 2‐phenyl‐2‐propyl benzodithioate as a chain‐transfer agent.…”

“…Then, pDPAMA was synthesized by the RAFT polymerization of DPAMA using 2‐phenyl‐2‐propyl benzodithioate as a chain‐transfer agent. [ 17 ] By evaluating the monomer conversion during the polymerization process, the degree of polymerization was estimated to be 65 (Figure S2, Supporting Information). After purification of the polymerization mixture, the obtained product was characterized by proton nuclear magnetic resonance ( 1 H NMR) and gel permeation chromatography (GPC) analyses to be pDPAMA with a unimodal molecular weight distribution ( M n = 6980, M w = 10 670, M n / M w = 1.528, using poly(ethylene glycol) (PEG) standard) ( Figure a,b).…”

Controlled polymerization of metal complex monomers – fabricating random copolymers comprising different metal species and nano-colloids

“…9,10 In general, the incorporation of metal complexes into the side chains is accomplished by mixing metal species with ligand-structured polymers (Scheme 1a). 5,6,11,12 However, this process is not suitable for preparing polymer chains that incorporate types of complexes with different metal species. It is difficult to control the metal components on the polymer chains by simply changing the feeding metal compositions to the polymer, because the ligand-binding affinity varies across metal species.…”

“…13,14 This approach differs from the widely adopted procedure, in which a polymer backbone with a ligand structure is prepared before the formation of metal complexes (Scheme 1a). 5,6,11,12 Notably, this approach achieved the synthesis of polymer chains containing two metal species in the polymer backbone by polymerizing monomers containing two metal species. 15 In this case, metal species along the polymer backbone can be fabricated in an ideal alternating manner.…”

“…[1][2][3][4] Polymers with metal complexes on side chains are very promising as high-performance hybrid materials because they enable in-solution locally concentrated states of the metal complexes to remain as secondary valence sites, with better catalytic activity and molecular recognition. [5][6][7][8] Because the electron density-dependent properties of metal complexes are affected by their molecular neighborhood, grafting polymer complexes with different metal species can further widen the scope of polymer applications. 9,10 In general, the incorporation of metal complexes into the side chains is accomplished by mixing metal species with ligand-structured polymers (Scheme 1a).…”