Abstract:Objectives: Universal implementation of cystic fibrosis (CF)
newborn screening (NBS) has led to the diagnostic dilemma of infants
with CF screen positive, inconclusive diagnosis (CFSPID), for which
there is limited guidance regarding prognosis and standardized care.
Rates of reclassification from CFSPID to CF vary and risk factors for
reclassification are unknown. We investigated whether clinical
characteristics are associated with risk of reclassification from CFSPID
to a CF diagnosis. Methods: Children with … Show more
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