Increase in arterial stiffness measures after bariatric surgery

Wang, Frances; Yang, Chao; Tanaka, Hirofumi; Coresh, Josef; Ndumele, Chiadi E; Matsushita, Kunihiro

doi:10.1016/j.atherosclerosis.2021.01.013

Cited by 5 publications

(3 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar to previous research [16,44,[54][55][56], our subjects have also shown a marked improvement in PWA parameters and, as such, a reduction of the general arterial stiffness (AS). Nevertheless, other studies did not find such changes in the AS.…”

Section: Discussionsupporting

confidence: 89%

The Effect of Bariatric Surgery on Microvascular Structure and Function, Peripheral Pressure Waveform and General Cardiovascular Risk: A Longitudinal Study

Karimzad,

Shokr,

Bellary

et al. 2023

JCM

View full text Add to dashboard Cite

Purpose: This study aims to assess the effect of bariatric surgery on retinal microvascular calibre, peripheral microvascular function, peripheral pressure waveforms, and the general cardiovascular disease (CVD) risk in obese individuals after undergoing Roux-en-Y gastric bypass (RYGB) surgery. Methods: A total of 29 obese participants were included in the study. All of the measurements were conducted at two time points: before and one year following the bariatric surgery procedure. General anthropometric data, as well as blood markers for glucose, cholesterol, and triglycerides were assessed in all individuals. In all participants, the Framingham risk score (FRS), and retinal vessel calibre measurements, using a Zeiss fundus camera and VesselMap software (ImedosSystems, Jena, Germany), were performed. Systemic arterial stiffness was measured by pulse wave analysis (PWA), and peripheral microvascular reactivity by way of digital thermal monitoring (DTM) in all participants. Results: As expected, various general anthropometric parameters, including body mass index (BMI), waist circumference and neck circumference, were significantly decreased post-surgery comparing to baseline in all individuals (all p < 0.001). In addition, their general CVD risk, as measured using FRS, was significantly improved (p < 0.001). At the retinal vascular level, central retinal artery equivalent (CRAE) as well as, central retinal vein equivalent (CRVE) had increased after surgery comparing to the baseline values (p = 0.003 and p = 0.007, respectively). In addition, both systemic arterial stiffness and peripheral microvascular reactivity had improved in all participants (p < 0.001 and p = 0.008 respectively). Conclusions: Our findings suggest that bariatric surgery has a positive effect on the overall vascular health, as well as on the general CVD risk of the obese patients undergoing this procedure.

show abstract

Section: Discussionsupporting

confidence: 89%

The Effect of Bariatric Surgery on Microvascular Structure and Function, Peripheral Pressure Waveform and General Cardiovascular Risk: A Longitudinal Study

Karimzad,

Shokr,

Bellary

et al. 2023

JCM

View full text Add to dashboard Cite

show abstract

“…The different trends in tonometric and CAVI-derived arterial stiffness should be carefully considered: central and peripheral arterial segments face different aging and stiffening processes due to a wide amount of anthropometric, structural, and physiological factors (48). When considering CAVI as an arterial stiffness index, it should be acknowledged that it is also affected by the perivascular tissue at the four limbs; therefore, a higher mass or density of the surrounding tissue and or a higher degree of tethering might dampen the propagation of the wave, resulting in a lower PWV (49). This may explain part of the association between sarcopenia and higher peripheral arterial stiffness.…”

Section: Discussionmentioning

confidence: 99%

Sarcopenia, sarcopenic obesity, and arterial stiffness among older adults

Fantin,

Giani,

Manzato

et al. 2024

Front. Cardiovasc. Med.

View full text Add to dashboard Cite

BackgroundAging is associated with a higher prevalence of sarcopenia, sarcopenic obesity (SO), and increased arterial stiffening, with possible detrimental effects on morbidity and mortality. The aim of this study was to assess the relationships between sarcopenia, SO, and different indexes of arterial stiffness in older adults.MethodsA total of 77 hospitalized patients (mean age 78.68 ± 9.65 years) were evaluated, obtaining anthropometric variables, biochemical samples, handgrip test, and body composition assessment. Arterial stiffness was evaluated by measuring both carotid-femoral pulse wave velocity (cfPWV), a proxy for central stiffness, and cardio-ankle vascular index (CAVI), as well as considering peripheral arteries. The population was sorted into four subgroups: obese, sarcopenic, SO, and controls.ResultsThe highest CAVI (11.31 ± 2.58) was found in sarcopenic patients. SO had the highest value of cfPWV (15.18 ± 8.44 m/s), even after adjustment for significant covariates. In multiple regressions, SO diagnosis resulted as a significant predictor of cfPWV (p = 0.03, R2 = 0.20), and sarcopenia diagnosis resulted as a predictor of CAVI (p = 0.042, R2 = 0.12).ConclusionsIn conclusion, a positive correlation is found between sarcopenia, SO, and arterial stiffness among older subjects. In particular, greater central arterial stiffness is associated with SO, outlining a remarkable effect on the cardiovascular risk profile.

show abstract

“…Studies have shown conflicting results regarding PWV; it has been reported to be decreased [22], unchanged [13], and even increased [23]. The most recent study published in 2021 [23 showed a paradoxical increase in arterial stiffness at 6 months after BS.…”

Section: Change In Macrovascular Variablesmentioning

confidence: 99%

Longitudinal Effect of Bariatric Surgery on Retinal Microcirculation and Target Organ Damage: the BASTOD Study

et al. 2022

View full text Add to dashboard Cite

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

show abstract

Increase in arterial stiffness measures after bariatric surgery

Cited by 5 publications

References 24 publications

The Effect of Bariatric Surgery on Microvascular Structure and Function, Peripheral Pressure Waveform and General Cardiovascular Risk: A Longitudinal Study

The Effect of Bariatric Surgery on Microvascular Structure and Function, Peripheral Pressure Waveform and General Cardiovascular Risk: A Longitudinal Study

Sarcopenia, sarcopenic obesity, and arterial stiffness among older adults

Longitudinal Effect of Bariatric Surgery on Retinal Microcirculation and Target Organ Damage: the BASTOD Study

Contact Info

Product

Resources

About