Increase in Adverse Health Effects Related to Synthetic Cannabinoid Use

Law, Royal; Schier, Josh; Martin, Colleen; Chang, Arthur; Wolkin, Amy; Schauben, Jay L.

doi:10.5210/ojphi.v8i1.6479

Cited by 42 publications

(66 citation statements)

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“…According to the US National Poison Data System records, the number of calls related to the use of the SC-induced side effects in 2015 showed a 229% increase compared to the previous year (4). Similarly, dramatic increase have been seen in intoxication cases due to use of SC in Japan in the last few years.…”

Section: Introductionmentioning

confidence: 94%

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Socio-demographic and Clinical Features of Young Adult Males Using Synthetic Cannabinoid (English)

Öznur¹,

Öznur²,

Bolu³

et al. 2018

J Clin Psy

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SUMMARYObject: Synthetic Cannabinoid (SC) use is becoming more widespread throughout the world. Studies that revealed user profiles indicate that the drug is especially popular among young men. Knowledge on sociodemographic, clinical characteristics and motivation for SC users in our country is limited. On the other hand, in spite of the increase of information known about symptoms of acute intoxication of SC use, physical and psychiatric consequences and loss of function due to longterm use of SC is limited. In this study, we aimed to investigate socio-demographic and clinical characteristics associated with SC use and the negative consequences caused by the use of SC. Methods: 166 male patients who admitted to the psychiatric outpatient clinic due to SC use disorder between November 2014 to April 2015 were enrolled in the study. Demographic data of patients, substance use characteristics, familial substance use, reasons for substance use, medical history, the problems related to drug use was questioned. Results: The age of onset for SC use was found to be 17.25 ± 2.30. SC using duration was 3.79 ± 2.15 years. The most common agents accompanying SC use were smoking (95.8%) and cannabis (88.6%). It was determined that 62.7% developed suicidal ideas due to SC use. Among psychiatric side effects, most common were euphoria, hallucinations, skepticism and suicidal ideation. About 1/3 of cases were found to live loss of business and legal issues depending on long-term SC use. 76.5% of the patients' consumed SC through inhalation and 22.9 % orally. It was determined that oral users began SC use at an earlier age than users via inhalation. Discussion: Despite the physical, mental, occupational, social and legal problems caused by the use of SC, it has become an important public health problem, especially among young men. Effective intervention programs for the use of outbreaking SCs need to be developed.

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Section: Introductionmentioning

confidence: 94%

“…As well as physical complications, behavioral pathologies and psychotic symptoms were also observed in these cases (5). In US National Poison Data System records of 2015, serious side effects has been found in 11.3% of the acute intoxication cases due to SC use (4).…”

Section: Introductionmentioning

confidence: 99%

Socio-demographic and Clinical Features of Young Adult Males Using Synthetic Cannabinoid (English)

Öznur¹,

Öznur²,

Bolu³

et al. 2018

J Clin Psy

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“…Thus, SCs toxicity reports in the United States increased from 349 in January, 2015, to 1501 in April of the same year (Law, Schier, Martin, Chang & Wolkin, 2015). Likewise, a study performed in the United States on a sample of 12000 adolescents found that up to 10% of the students had used SCs in the previous 12 months and 3.2% acknowledged a frequent use of at least six times in the same time frame (Palamar & Acosta, 2015).…”

Section: Synthetic Cannabinoidsmentioning

confidence: 99%

An approach to the new psychoactive drugs phenomenon

Dolengevich-Segal

Rodríguez-Salgado

Gómez-Arnau

et al. 2017

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Background. The new psychoactive drugs (NPD) are those that represent a danger to public health and are not prohibited by conventions on international narcotics. The concept also includes new contexts and new routes of consumption as well as novel ways of distribution, notably Internet. The risks associated with NPD consumption are largely unknown to users and to health care providers. Objective. To integrate the existing evidence regarding the main NPD in terms of description, epidemiology, psychopharmacology, medical complications and psychoactive effects. Method. To review relevant and updated clinical information on NPD obtained from specialized books and indexed scientific journals (PubMed/Medline, Google Scholar, Scopus), as well as official documents edited by international organizations dedicated to the epidemiologic analysis of drug abuse and Internet websites and forums managed by psychoactive substance users. Results. Aspects of clinical and pharmacological interest are described comprehensively, together with epidemiological data and risks associated to the consumption of the most relevant NPD: synthetic cannabinoids, synthetic cathinones, NBOMe series, indoleamines, piperazines, hallucinogenic mushrooms (Psilocybe SP.), synthetic opioids, plant products (khat, kratom, Salvia divinorum, ayahuasca) and dissociative anesthetics. Discussion and conclusion. The emergence of the NPD is a phenomenon on the rise with important consequences for public health. Learning about new trends in drug consumption and its potential risks should be essential for the medical professional. New research is needed in order to understand the phenomenon of the NPD and its pharmacological, clinical and legal implications.

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“…The commonly reported adverse effects of SC use by the CDC are drowsiness or lethargy (26.3%), emesis (16.4%), confusion (4.2%), tachycardia (29.0%), and agitation (35.3%) [2]. Spaderna et al have summarized the less common adverse effects reported in the literature affecting a large range of organ systems including neurological, cardiovascular, psychological, and gastrointestinal adverse effects [3].…”

Section: Paul Et Al 432mentioning

confidence: 99%