Incorporation of pretreatment leukocytosis and thrombocytosis into the FIGO staging system for prognosis in surgically treated endometrial cancer

Yokoi, Eriko; Mabuchi, Seiji; Komura, Naoko; Shimura, Kentaro; Matsumoto, Yoshihisa; Kimura, Tadashi

doi:10.1002/ijgo.13327

Cited by 2 publications

(1 citation statement)

References 26 publications

(47 reference statements)

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“…The FIGO staging include the comprehensive histological grade, nuclear grade, depth of invasion, site of invasion, metastasis, ascites cytology, which are used to guide the development of treatment plans and prognosis for endometrial carcinoma. Most patients with stage III and IV have metastasized and need to expand the scope of surgery [ 32 ]. And the tumor is difficult to completely remove, not only the prognosis of treatment is poor, but also the incidence of SSI is higher [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Predictive factors of surgical site infection after hysterectomy for endometrial carcinoma: a retrospective analysis

Shi

Zhang

et al. 2021

BMC Surg

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Background Surgical site infection (SSI) is a common postoperative complication. We aimed to analyze the potential risk factors of SSI in patients with endometrial carcinoma. Methods Patients with endometrial carcinoma who underwent surgery treatment in our hospital from Sept 1, 2018 to August 31, 2020 were included. We retrospectively compared the characteristics of SSI and no SSI patients, and logistic regression analyses were performed to identify the risk factors of SSI in patients with endometrial carcinoma. Results A total of 318 postoperative patients with endometrial carcinoma were included. The incidence of SSI in patients with endometrial carcinoma was 14.47 %. There were significant differences on the FIGO stage, type of surgery, durations of drainage, postoperative serum albumin and postoperative blood sugar (all p < 0.05), and no significant differences on the age, BMI, hypertension, diabetes, hyperlipidemia, estimated blood loss, length of hospital stay were found (all p > 0.05). FIGO stage IV (HR3.405, 95 %CI 2.132–5.625), open surgery (HR2.692, 95 %CI 1.178–3.454), durations of drainage ≥ 7 d (HR2.414,95 %CI 1.125–2.392), postoperative serum albumin < 30 g/L (HR1.912,95 %CI 1.263–2.903), postoperative blood sugar ≥ 10 mmol/L (HR1.774,95 %CI 1.102–2.534) were the independent risk factors of SSI in patients with endometrial carcinoma (all p < 0.05). Conclusions Measures including reasonable control of serum albumin and blood glucose levels, minimally invasive surgery as much as possible, timely assessment of drainage and early removal of the tube may be beneficial to reduce the postoperative SSI in in patients with endometrial carcinoma.

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Section: Discussionmentioning

confidence: 99%

Predictive factors of surgical site infection after hysterectomy for endometrial carcinoma: a retrospective analysis

Shi

Zhang

et al. 2021

BMC Surg

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Preoperative leukocytosis correlates with unfavorable pathological and survival outcomes in endometrial carcinoma: A systematic review and meta-analysis

Abu‐Zaid

Alomar

Baradwan

et al. 2021

European Journal of Obstetrics & Gynecology and Reproductiv

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Incorporation of pretreatment leukocytosis and thrombocytosis into the FIGO staging system for prognosis in surgically treated endometrial cancer

Abstract: Objective: To investigate the impact of incorporating pretreatment leukocytosis and/ or thrombocytosis in the FIGO staging system on prognostic prediction among women with surgically treated endometrial cancer.

Cited by 2 publications

References 26 publications

Predictive factors of surgical site infection after hysterectomy for endometrial carcinoma: a retrospective analysis

Predictive factors of surgical site infection after hysterectomy for endometrial carcinoma: a retrospective analysis

Preoperative leukocytosis correlates with unfavorable pathological and survival outcomes in endometrial carcinoma: A systematic review and meta-analysis

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