Incorporation of magnetic NaX zeolite/DOX into the PLA/chitosan nanofibers for sustained release of doxorubicin against carcinoma cells death in vitro

Biodegradable polymers, current trends of research and their applications, a review

“…Due to well-known antioxidant activity of both loaded components and good qualities of PLA-PHB biocomposites, these are promising materials for biodegradable film applications (agricultural mulch films, films for food packaging) [86]. In a brand-new in vitro study, Abasian et al [87] have successfully incorporated the NaX/Fe 3 O 4 nanoparticles and doxorubicin (DOX) into the PLA/chitosan nanofibers. These prepared nanofibers show excellent potential in local chemotherapy of carcinoma tumors.…”

Nanodiamond-containing composites for tissue scaffolds and surgical implants: A review

“…The application of ND-Dox complexes increased the circulation half-time to 10 times of unmodified doxorubicin, and the doxorubicin expelling capacity of tumors decreased. Other benefits of drug delivery systems based on ND-Dox are reported to be a noticeable decrease in the tumor size, the absence of myelosuppression, and the absence of mortality in the case of high delivery doses [123,165,166]. Besides, delivering small molecules polyethyleneimine 800 (PEI800)-coated NDs were investigated for the delivery of nucleic acids.…”

An overview of the development of composites containing Mg and Zn for drug delivery

“…Controlled drug delivery systems (DDSs) are known as formulations or devices that can transport therapeutic agents in the body for their action at specific site, at desired rate, for specific time, and release of the drugs to the target location [46][47][48]. Therefore, these systems act as an interface between the drug and the patient and help us to develop personalized medicine including pharmaco proteomics, pharmacometrics, and pharmacogenomics.…”