Incorporating Imaging Into the Locoregional Management of Breast Cancer

Lourenço, Ana P.; Mainiero, Martha B.

doi:10.1016/j.semradonc.2015.09.006

Cited by 2 publications

(1 citation statement)

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“…Lesion characterization by DCE-MRI depends on the difference in vascular supply between normal and neoplastic tissue. Neoplastic tissue demonstrates contrast uptake due to the development of neovascularization [6].…”

Section: Introductionmentioning

confidence: 99%

Can contrast-enhanced mammography replace dynamic contrast-enhanced MRI in the assessment of sonomammographic indeterminate breast lesions?

Kamal

Hanafy

Mansour

et al. 2020

Egypt J Radiol Nucl Med

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Background: Dynamic contrast-enhanced MRI of the breast has been used for several years in the assessment of indeterminate mammographic findings. Contrast-enhanced mammography is a relatively novel imaging technique that has shown comparable sensitivity and specificity to MRI. Contrast-enhanced mammography is a relatively easy feasible study with high sensitivity and low cost. Our aim was to assess the feasibility of replacing dynamic contrastenhanced (DCE)-MRI by contrast-enhanced mammography in the assessment of sonomammographic indeterminate lesions (BIRADS 3 and 4). Results: The study included 82 patients with 171 breast lesions. They all performed contrast-enhanced mammography and dynamic contrast-enhanced MRI. DCE-MRI sensitivity and NPV were significantly higher than those of contrast-enhanced mammogram (CEM). The overall accuracy of MRI was better than that of CEM; however, no statistically significant difference could be detected. Conclusion: Contrast-enhanced mammography and dynamic contrast-enhanced MRI improved the characterization of breast lesions. CEM showed slightly lower sensitivity and accuracy compared to MRI; however, because of being relatively easy, available, cheap, and acceptable by women, CEM can replace DC-MRI as a problem-solving tool in the characterization of indeterminate breast lesions.

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Section: Introductionmentioning

confidence: 99%