Incontinentia pigmenti: a case with an unusual course

Abstract

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Vaccination as a Probable Cause of Incontinentia Pigmenti Reactivation

“…The skin lesions of IP occur in four classic stages, evolving over months to years: a vesicobullous stage, a verrucous stage, a hyperpigmented stage, and a hypopigmented (atrophic) stage (3). It is not necessary that all stages occur, and several may occur concurrently (6). However, erythematous vesicles (stage 1) occur in over 90% of IP patients (7).…”

“…Of these, seven had a preceding trigger and eight involved multiple (>1) recurrences (10). Recurrence was usually preceded by viral infection and/or fever (6,8,10,11), but has also appeared after laser treatment (12). IP reactivation may occur without a preceding trigger as well (2,10,13).…”

Disorders of pigmentation

“…656 Vesicular and trunk. 703 Vesicular recurrences, later in life, are rare. 700 Rarely, they are papular in type.…”

A case of incontinentia pigmenti reactivation after 12-month immunizations

“…Previous instances of late recurrences were most often associated with fevers and systemic infections. 5 , 6 Other instances of IP reactivation have been associated with the supplementation of estrogen to young children with incompletely formed external genitalia and with the use of laser therapy to reverse hyperpigmentation in old IP lesions. 7 , 8 Recurrence is not always associated with a specific trigger.…”