Inclusion of Organic Pollutants in Cyclodextrins and Derivatives

Baudin, Cécile; Péan, Christophe; Perly, Bruno; Gosselin, Pascal

doi:10.1080/03067310008032685

Cited by 30 publications

(12 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, the pentapeptide conformation affects the stability of the pentapeptide/β-CD inclusion complex. In contrast, the pentapeptide/α-CD inclusion complex was not affected by the oligopeptide conformation (27,20, and 20 M −1 for free Try, YIGSR, and YGGFL, respectively).…”

Section: Ii) Complexation Of Peptides and Proteins And Some Applicationsmentioning

confidence: 88%

“…As natural CDs and their derivatives are able to encapsulate a wide range of guest molecules into their cavity, they can be used in a wide range of applications including analytical chemistry [21,22,31], agriculture [15], food technology [16], catalysis [23][24][25]32], cosmetics [26], textile processing [28,33], and environmental protection technologies [27,34]. Nevertheless, the first global consumer of CDs is clearly the pharmaceutical industry [35,36].…”

Section: Iii) Applications Of Cyclodextrinsmentioning

confidence: 99%

“…As their water solubility differs significantly, a great variety of modified CDs has been developed to improve the stability and the solubility of inclusion complexes [8][9][10]. Nowadays, CDs are widely applied in many fields [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28] due to their host-guest properties, their origins (produced from starch by enzymatic conversion), their relatively low prices, their easy modifications, their biodegradability and their low toxicity. Moreover, CDs are able to interact with a wide range of biomol- ecules opening the way for many biological applications.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Interactions between cyclodextrins and cellular components: Towards greener medical applications?

Leclercq¹

2016

Beilstein J. Org. Chem.

View full text Add to dashboard Cite

In the field of host–guest chemistry, some of the most widely used hosts are probably cyclodextrins (CDs). As CDs are able to increase the water solubility of numerous drugs by inclusion into their hydrophobic cavity, they have been widespread used to develop numerous pharmaceutical formulations. Nevertheless, CDs are also able to interact with endogenous substances that originate from an organism, tissue or cell. These interactions can be useful for a vast array of topics including cholesterol manipulation, treatment of Alzheimer’s disease, control of pathogens, etc. In addition, the use of natural CDs offers the great advantage of avoiding or reducing the use of common petroleum-sourced drugs. In this paper, the general features and applications of CDs have been reviewed as well as their interactions with isolated biomolecules leading to the formation of inclusion or exclusion complexes. Finally, some potential medical applications are highlighted throughout several examples.

show abstract

Section: Ii) Complexation Of Peptides and Proteins And Some Applicationsmentioning

confidence: 88%

Section: Iii) Applications Of Cyclodextrinsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Interactions between cyclodextrins and cellular components: Towards greener medical applications?

Leclercq¹

2016

Beilstein J. Org. Chem.

View full text Add to dashboard Cite

show abstract

“…Industrial production of cyclodextrins has benefited from the biocatalytic process since a-, b-, and c-CD could be produced on a large scale with a high conversion rate of substrates such as amylase and potato starch and without use of organic solvents to precipitate the CDs. The utility value attached to CGTases has also encouraged usage of CDs for improving diverse products such as food, cosmetics, and pharmaceuticals [25,41,242]. Some recent reports also document methods for enhanced production of CGTases, some from alkalitolerant organisms [17,32,43,44,93,107,117,148,160,168,174,175,215,219,260,261,282].…”

Section: Amylasementioning

confidence: 97%

Alkaliphilic bacteria: applications in industrial biotechnology

Sarethy

Saxena

Kapoor

et al. 2011

J Ind Microbiol Biotechnol

118

View full text Add to dashboard Cite

Alkaliphiles are interesting groups of extremophilic organisms that thrive at pH of 9.0 and above. Many of their products, in particular enzymes, have found widespread applications in industry, primarily in the detergent and laundry industries. While the enzymes have been a runaway success from the industrial point of view, many more products have been reported from alkaliphiles such as antibiotics and carotenoids. Less known are their potential for degradation of xenobiotics. They also play a key role in biogeocycling of important inorganic compounds. This review provides an insight into the huge diversity of alkaliphilic bacteria, the varied products obtained from them, and the need for further investigations on these interesting bacteria.

show abstract

“…CDs are ring-shaped molecules with a hydrophilic outer surface and a hydrophobic cavity [Baudin et al, 2000]. The large size of the non-polar cavity of ␤ -CD is most suitable to accommodate molecules such as drugs and aromatics compared to ␣ -and ␥ -CD.…”

mentioning

confidence: 99%

Effect of Signal Peptides on the Secretion of β-Cyclodextrin Glucanotransferase in <b><i>Lactococcus lactis</i></b> NZ9000

Subramaniam¹,

Baradaran²,

Rosli³

et al. 2012

Microb Physiol

View full text Add to dashboard Cite

Cyclodextrin glucanotransferase (CGTase) is an extracellular enzyme which catalyzes the formation of cyclodextrin from starch. The production of CGTase using lactic acid bacterium is an attractive alternative and safer strategy to produce CGTase. In this study, we report the construction of genetically modified Lactococcus lactis strains harboring plasmids that secrete the Bacillus sp. G1 β-CGTase, with the aid of the signal peptides (SPs) SPK1, USP45 and native SP (NSP). Three constructed vectors, pNZ:NSP:CGT, pNZ:USP:CGT and pNZ:SPK1:CGT, were developed in this study. Each vector harbored a different SP fused to the CGTase. The formation of halo zones on starch plates indicated the production and secretion of β-CGTase by the recombinants. The expression of this enzyme is shown by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and zymogram analysis. A band size of ∼75 kDa corresponding to β-CGTase is identified in the intracellular and the extracellular environments of the host after medium modification. The replacement of glucose by starch in the medium was shown to induce β-CGTase production in L. lactis. Although β-CGTase production is comparatively low in NZ:SPK1:CGT, the SP SPK1 was shown to have higher secretion efficiency compared to the other SPs used in this study.

show abstract

Inclusion of Organic Pollutants in Cyclodextrins and Derivatives

Cited by 30 publications

References 9 publications

Interactions between cyclodextrins and cellular components: Towards greener medical applications?

Interactions between cyclodextrins and cellular components: Towards greener medical applications?

Alkaliphilic bacteria: applications in industrial biotechnology

Effect of Signal Peptides on the Secretion of β-Cyclodextrin Glucanotransferase in <b><i>Lactococcus lactis</i></b> NZ9000

Contact Info

Product

Resources

About