Incisional recurrence of gallbladder cancer after laparoscopic cholecystectomy

Reliability of frozen section diagnosis of gallbladder tumor for detecting carcinoma and depth of its invasion

“…Some recommended the procedure for a laparoscopic excisional biopsy of the gallbladder [13]. Others proposed that whenever gallbladder carcinoma is suspected, open cholecystectomy should be done [11,12,[15][16][17][18][19][20]. The timing of the second operation is important in gallbladder carcinoma because of the early and rapid recurrence.…”

“…The surgical problems concerning suspected or unsuspected gallbladder carcinoma are almost the same at the era of open and laparoscopic cholecystectomies, except for early port-site recurrence of gallbladder carcinoma [15][16][17][18][19][20][21][22][31][32][33][34][35][36][37][38][39][40][41][42][43][44], which is not seen at the era of open cholecystectomy. It is not well known if to excise the trocar sites is enough or not because peritoneal dissemination occurs simultaneously.…”

Peritoneal seeding of gallbladder cancer after laparoscopic cholecystectomy

“…As was also the case in our patient, metastatic seedings generally become symptomatic or clinically apparent after a latent period of a few months following laparoscopic cholecystectomy [14]. Such seedings are usually found at or near the trocar site that was used for organ withdrawal [2,3,9,11,12,14,15]. This fact has led to the recommendation that a nonporous bag be used for organ retrieval if any suspicion of malignancy is raised intraoperatively [3,14,15].…”

“…Such seedings are usually found at or near the trocar site that was used for organ withdrawal [2,3,9,11,12,14,15]. This fact has led to the recommendation that a nonporous bag be used for organ retrieval if any suspicion of malignancy is raised intraoperatively [3,14,15]. Nevertheless, our case report demonstrates that even with the correct usage of such a bag seeding of neoplastic cells cannot be avoided with absolute certainty.…”

»Sister Mary Joseph’s nodule« bei Gallenblasenkarzinom

“…11 ner benigner Tumoren wie Naevuszellnaevi, Dermatofibrome und Neurofibrome sowie schließlich tumorartige Formationen wie Endometriose, Papillome, Teratome, Fremdkörpergranulome sowie Omphalolithen. Einige Krankheitsfälle wurden berichtet, in denen es im Gefolge einer Laparaskopie zum Auftreten von Nabelmetastasen kam (3,8,9,16).In der Untersuchung von Steck und Helwig(14) war bei 97 von 152 Patienten die Nabelmetastase das erste klinische Hinweiszeichen auf den malignen Tumor, wie dies auch bei dem hier beschriebenen Patienten der Fall war. Die Prognose einer kutanen Nabelmetastase ist meist ungünstig.…”