Incidental Focal 18F-FDG Uptake in the Prostate: Clinical Significance and Differential Diagnostic Criteria

Cho, Suk Kyong; Choi, Joon Young; Yoo, Jang; Cheon, Miju; Lee, Ji Young; Hyun, Seung Hyup; Lee, Eun Jeong; Lee, Kyung-Han; Kim, Byung‐Tae

doi:10.1007/s13139-011-0092-x

Cited by 24 publications

(29 citation statements)

References 19 publications

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“…This low frequency was similar to results published by Cho et al. (2011) . Incidental prostate findings may be indicative of carcinoma, hyperplasia, or prostatitis .…”

Section: Discussionsupporting

confidence: 91%

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Retrospective chart analysis of incidental findings detected by ¹⁸F‐fluorodeoxyglucose‐PET/CT in patients with cutaneous malignant melanoma

Conrad

Winkens

Kaatz

et al. 2016

J Deutsche Derma Gesell

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The diagnostic use of FDG-PET/CT is routinely recommended for stage IIC melanoma and higher, and is widely accepted as indication. This study effectively identified otherwise undetected cancers, especially colorectal malignancies. Early interventions were possible in most cases. Incidental findings on FDG-PET/CT should be worked up with appropriate diagnostic measures, considering the patient's condition and wishes.

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“…This low frequency was similar to results published by Cho et al. (2011) . Incidental prostate findings may be indicative of carcinoma, hyperplasia, or prostatitis .…”

Section: Discussionsupporting

confidence: 91%

“…Bei zwei der 181 Melanom-Patienten wurden zufällig Foci in der Prostata gefunden, wovon einer sich als bösartig erwies (Abbildung 3 ). Diese geringe Häufi gkeit entspricht den von Cho et al (2011) publizierten Ergebnissen [ 37 ] . Zufallsbefunde in der Prostata können auf ein Karzinom, Hyperplasie oder Prostatitis hinweisen [ 38 ] .…”

Section: Prostataunclassified

Retrospective chart analysis of incidental findings detected by ¹⁸F‐fluorodeoxyglucose‐PET/CT in patients with cutaneous malignant melanoma

Conrad

Winkens

Kaatz

et al. 2016

J Deutsche Derma Gesell

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“…Only a few reports have described incidental prostate uptake on FDG-PET/CT (3). In the present study, we investigated the frequency and clinical significance of incidental prostate uptake on FDG-PET/CT and examined the relationship between the location of FDG uptake and prostate calcification.…”

Section: Introductionmentioning

confidence: 99%

Incidental prostate 18F-FDG uptake without calcification indicates the possibility of prostate cancer

et al. 2014

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Incidental 18F-fluorodeoxyglucose (18F-FDG) uptake in the prostate is often experienced in clinical practice; however, it is difficult to determine whether incidental uptake is indicative of a malignancy or benign state based on the maximum standardized uptake value (SUVmax). In the present study, we investigated the clinical significance of incidental prostate uptake by 18F-FDG positron emission tomography (PET)/CT, and examined the differences between malignant and benign uptake from a clinicopathological viewpoint. We reviewed 3,236 male subjects who underwent 18F-FDG PET/CT scans at Hirosaki University Hospital (Japan) from 2008 to 2012 in order to identify cases of incidental prostate FDG uptake. The final diagnosis was made by serum prostate-specific antigen (PSA) levels, biopsy, imaging studies and clinical follow-up with PET findings. Incidental FDG uptake of the prostate was observed in 53 cases (2%). Four cases were excluded due to insufficient clinical data, and 49 cases were included in the present study. Of the 49 cases, 8 (16%) had prostate cancer, while 41 (84%) were benign. All 8 malignant cases had high uptake areas, e.g. in the prostate peripheral zone, where there was no coexistence of calcification or FDG uptake. Of the 41 benign cases, 19 had high uptake in the inner zone, 17 in the peripheral zone, and 5 in both the inner and peripheral zones. Of the 41 cases, 18 (44%) showed FDG uptake coexisting with prostatic calcification. Incidental prostate 18F-FDG uptake infrequently signifies prostate cancer; however, FDG uptake not coexisting with calcification indicates the possibility of prostate cancer and should be included in the differential diagnosis for performing other clinical examinations.

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“…Many literature reports suggest PIU is not infrequent and is often indicative of malignancy [11][12][13][14][15][16][17][18]. Results on the prevalence of PIU and the incidence of malignancy in studies available in the literature and in this work are summarised in Table 1.…”

Section: Discussionmentioning

confidence: 89%

Multicentre study of 18F-FDG-PET/CT prostate incidental uptake

et al. 2015

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Incidental Focal 18F-FDG Uptake in the Prostate: Clinical Significance and Differential Diagnostic Criteria

Abstract: Although incidental focal (18)F-FDG uptake in the prostate is not common, the incidence of cancer with focal uptake is not low. Therefore, these findings deserve further evaluation. The location of the focal prostate uptake may help with the selection of high-risk prostate cancer patients.

Cited by 24 publications

References 19 publications

Retrospective chart analysis of incidental findings detected by ¹⁸F‐fluorodeoxyglucose‐PET/CT in patients with cutaneous malignant melanoma

Retrospective chart analysis of incidental findings detected by ¹⁸F‐fluorodeoxyglucose‐PET/CT in patients with cutaneous malignant melanoma

Incidental prostate 18F-FDG uptake without calcification indicates the possibility of prostate cancer

Multicentre study of 18F-FDG-PET/CT prostate incidental uptake

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Incidental Focal 18F-FDG Uptake in the Prostate: Clinical Significance and Differential Diagnostic Criteria

Cited by 24 publications

References 19 publications

Retrospective chart analysis of incidental findings detected by 18F‐fluorodeoxyglucose‐PET/CT in patients with cutaneous malignant melanoma

Retrospective chart analysis of incidental findings detected by 18F‐fluorodeoxyglucose‐PET/CT in patients with cutaneous malignant melanoma

Incidental prostate 18F-FDG uptake without calcification indicates the possibility of prostate cancer

Multicentre study of 18F-FDG-PET/CT prostate incidental uptake

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Product

Resources

About

Retrospective chart analysis of incidental findings detected by ¹⁸F‐fluorodeoxyglucose‐PET/CT in patients with cutaneous malignant melanoma

Retrospective chart analysis of incidental findings detected by ¹⁸F‐fluorodeoxyglucose‐PET/CT in patients with cutaneous malignant melanoma