Incidental Findings Suggestive of COVID-19 in Asymptomatic Patients Undergoing Nuclear Medicine Procedures in a High-Prevalence Region

Albano, Domenico; Bertagna, Francesco; Bertoli, Mattia; Bosio, Giovanni; Lucchini, Silvia; Motta, Federica; Panarotto, Maria Beatrice; Peli, Alessia; Camoni, Luca; Bengel, Frank M.; Giubbini, Raffaele

doi:10.2967/jnumed.120.246256

Cited by 165 publications

(184 citation statements)

References 13 publications

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“…Therefore, the hypothesis that 18 F-FDG PET/CT is useful in the evaluation of COVID-19 pneumonia due to the peculiar metabolic behavior of this infection is excessive and not clearly demonstrated until now. On the other hand, nuclear medicine physicians should pay attention to incidental CT findings of interstitial pneumonia (with ground-glass opacities) suspected for COVID-19 infection detected at 18 F-FDG PET/CT, as demonstrated by some recent reports [6,7]. In clinical practice, the risk to have asymptomatic patients with COVID-19 infection who undergo nuclear medicine procedures including 18 F-FDG PET/CT is not negligible [6,7] and this is the "reality" about 18 F-FDG PET/CT and COVID-19 infection.…”

mentioning

confidence: 99%

The role of 18F-FDG PET for COVID-19 infection: myth versus reality

Treglia

2020

Clin Transl Imaging

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mentioning

confidence: 99%

The role of 18F-FDG PET for COVID-19 infection: myth versus reality

Treglia

2020

Clin Transl Imaging

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“…It remains a good practice to scrutinize the CT component of hybrid imaging studies. Knowledge of incidental chest imaging findings of COVID-19 will continue to be necessary, in case of a reemergence of the SARS-CoV-2 or new atypical instances of viral pneumonia [18].…”

Section: Incidental Chest Imaging Findingsmentioning

confidence: 99%

Nuclear medicine services after COVID-19: gearing up back to normality

Huang

Gnanasegaran

Páez

et al. 2020

Eur J Nucl Med Mol Imaging

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“…A few reports of patients with COVID-19 have been described by 18 F-FDG PET/CT, mostly symptomatic patients with COVID-19 respiratory disease that include dry cough, shortness of breath and fever [5][6][7][10][11][12][13]. However, a wide range of symptoms have been reported, ranging from asymptomatic or mild symptoms [8,12] to severe illness [5,7,11,13]. These symptoms may appear at 2 to 14 days after exposure to the coronavirus SARS-CoV-2.…”

Section: Discussionmentioning

confidence: 99%

“…On the other hand, 18 F-FDG PET/CT cannot be routinely used in the diagnosis of a pneumonia including the primary diagnosis of COVID-19. Recently a few cases of COVID19 have been described by 18 F-FDG PET/CT [6][7][8][9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Incidental 18F-FDG PET/CT finding of COVID-1 pneumonia in asymptomatic patient diagnosed with lung abscess metastasis

Mestre-Fusco

Velasco-Nuño

Negre-Busó

et al. 2020

Preprint

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A 66-year-old male patient, with chronic respiratory disease and right colon resection in March 2017 for colon low-grade adenocarcinoma was assessed for recurrence suggested by elevated levels of tumor marker and no evidence of oncological disease by CT scan. 18F-FDG PET/CT showed bilateral multiple peripheral FDG-avid foci that matched with a peripheral predominant ground-glass opacities (GGOs) observed in lower lobes and multiple FDG-positive enlarged lymph nodes were also identified in the mediastinum. Patient was hospitalized in March 14th 2020, one day after PET/CT scan, with cough, wheezing and fever, and was treated with anti-inflammatory drugs. A first SARS-CoV-2 RT-PCR in March 15th resulted as negative and patient was treated with antibiotic therapy lead to an improvement of respiratory symptoms. PET/CT scan was interpreted as a pneumonia foci. A deteriorating patient condition was observed, with respiratory symptomatology progression, fatigue and D-Dimer elevation and a new RT-PCR resulted positive. A week after PET/CT scan, hospitalization in intensive care unit was necessary for rapidly disease progression and severe respiratory distress syndrome and patient died four days later.

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Incidental Findings Suggestive of COVID-19 in Asymptomatic Patients Undergoing Nuclear Medicine Procedures in a High-Prevalence Region

Cited by 165 publications

References 13 publications

The role of 18F-FDG PET for COVID-19 infection: myth versus reality

The role of 18F-FDG PET for COVID-19 infection: myth versus reality

Nuclear medicine services after COVID-19: gearing up back to normality

Incidental 18F-FDG PET/CT finding of COVID-1 pneumonia in asymptomatic patient diagnosed with lung abscess metastasis

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