Incident changes of rotavirus enteritis among children during the coronavirus disease-2019 pandemic in Hangzhou, China

Fang, Chi; Zhou, Zheng; Li, Jianping; Zhou, Mingming

doi:10.1016/j.jinf.2021.09.007

Cited by 7 publications

(6 citation statements)

References 7 publications

(10 reference statements)

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“…8 Infants aged younger than 3 months generally have milder infection symptoms, potentially due to the protective effects of maternal antibodies. 9 Children aged 4 to 23 months are at the highest risk of severe rotavirus disease because the immune system of infants and toddlers in this age range is not fully developed, and repeated infections frequently occur. 10 However, with each subsequent infection, immunity gradually increases, so symptoms are milder after reinfection.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors of Convulsions in Children With Rotavirus Gastroenteritis and Construction of a Nomogram Prediction Model

Yang,

Sun,

Dai

2024

Pediatr Emer Care

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Objective This study aims to investigate and analyze the risk factors of convulsions in children with rotavirus gastroenteritis and to construct a nomogram prediction model. Methods A retrospective analysis was performed on 940 cases of pediatric patients with rotavirus gastroenteritis treated in our hospital from December 2017 to December 2022. Based on whether convulsions occurred during hospitalization, patients were divided into the convulsion group (n = 135) and the convulsion-free group (n = 805). Clinical information of patients in both groups was collected, logistic regression analysis was carried out to analyze the convulsion risk factors pertaining to children with rotavirus gastroenteritis, and a nomogram prediction model was constructed. Results The univariate analysis revealed that fever, frequency of diarrhea, white blood cell count, blood calcium level, blood glucose level, CO2CP, creatine kinase myocardial band (CK-MB), and blood pH value were all factors that display statistically significant differences at the level of P = 0.05. Then, logistic regression analysis was carried out, taking the occurrence of such convulsions as the dependent variable and the aforementioned factors as independent variables. The results show that fever, frequency of diarrhea, blood calcium, CO2CP, and CK-MB were the independent risk factors (P < 0.05), whereas the area under the receiver operating characteristic curve (area under the curve) of the constructed nomogram prediction model based on these factors was 0.842 (95% confidence interval, 0.821–0.914). Conclusions Frequency of diarrhea, blood calcium, CO2CP, and CK-MB are independent risk factors for the occurrence of convulsions in children with rotavirus gastroenteritis. The nomogram prediction model constructed based on these risk factors provides guidance and value in effectively preventing and controlling convulsions in children with rotavirus gastroenteritis.

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Section: Discussionmentioning

confidence: 99%

Risk Factors of Convulsions in Children With Rotavirus Gastroenteritis and Construction of a Nomogram Prediction Model

Yang,

Sun,

Dai

2024

Pediatr Emer Care

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“…As of 13 April 2020, no local cases were reported in Zhejiang Province, and no local cases were reported in Hangzhou on 20 February 2020. 20 …”

Section: Methodsmentioning

confidence: 99%

“…As a result, life gradually returns to what it was before the COVID‐19 pandemic. As of 13 April 2020, no local cases were reported in Zhejiang Province, and no local cases were reported in Hangzhou on 20 February 2020 20 …”

Section: Methodsmentioning

confidence: 99%

“…As of 13 April 2020, no local cases were reported in Zhejiang Province, and no local cases were reported in Hangzhou on 20 February 2020. 20 We retrospectively analyzed pregnant women who underwent oral glucose tolerance tests (OGTT) from 2019 to 2021 at the Women's Hospital of Zhejiang University School of Medicine. Our hospital is the largest obstetrics and gynecology specialty hospital in Zhejiang Province, with nearly 20 000 deliveries per year.…”

Section: Participants and Study Designmentioning

confidence: 99%

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Gestational diabetes mellitus in the COVID‐19 pandemic: A retrospective study from Hangzhou, China

Yin

et al. 2022

Journal of Diabetes

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Aims Our study aimed to investigate changes in the prevalence of gestational diabetes mellitus (GDM) in the COVID‐19 pandemic and postpandemic era and the risk of adverse pregnancy outcomes in pregnant women diagnosed with GDM during the blockade period. Methods First, we investigated changes in the prevalence of GDM and the population undergoing oral glucose tolerance tests (OGTT) after the COVID‐19 pandemic. We then collected clinical information from pregnant women diagnosed with GDM to explore the risk of adverse pregnancy outcomes in pregnant women with GDM during the COVID‐19 pandemic. Results After the COVID‐19 pandemic, the proportion of pregnant women in the total number of outpatient OGTT tests decreased yearly. The ratio was 81.30%, 79.71%, and 75.48% from 2019 to 2021, respectively, with the highest proportion of pregnant women in February 2020 (92.03%). The prevalence of GDM was higher in March 2020 compared to the same period in 2019. However, from 2019 to 2021, the prevalence decreased year by year with 21.46%, 19.81%, and 18.48%, respectively. The risk of adverse pregnancy outcomes for pregnant women diagnosed with GDM during the most severe period of the COVID‐19 pandemic did not differ from before the COVID‐19 pandemic. Conclusions After the COVID‐19 pandemic, the prevalence of GDM increased during the most severe period of the epidemic, but the overall prevalence of GDM decreased year by year. In addition, the pandemic did not change the risk of adverse pregnancy outcomes in pregnant women with GDM.

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“…Following the emergence of COVID-19, a number of reports have indicated perturbaMons in in seasonality, prevalence and incidence of common enteric viruses associated with diarrhoea disease. For instance, in France 3 , Poland 4 , China 5,6 and USA 7 , the prevalence of RVA during the year 2020 was lower compared to 2018 and 2019. However, in 2021 there was a surge of RVA cases in these countries.…”

Section: Introduc-onmentioning

confidence: 93%

Temporal changes in the positivity rate of common enteric viruses among paediatric admissions in coastal Kenya, in the period spanning the COVID-19 pandemic, 2019-2022

Lambisia

Murunga

Mutunga

et al. 2023

Preprint

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Background The non-pharmaceutical interventions (NPIs) implemented to curb the spread of SARS_CoV_2 early in the COVID_19 pandemic years, disrupted the activity of other respiratory viruses. There is limited data from low and middle income countries (LMICs) to determine whether COVID_19 NPIs also impacted the epidemiology of enteric viruses. We investigated the changes in infection patterns of common enteric viruses among hospitalised children who presented with diarrhoea to a referral hospital in coastal Kenya, in the period spanning the COVID_19 pandemic. Methods A total of 870 stool samples from children under 13 years of age admitted to Kilifi County Hospital between January 2019, and December 2022 were screened for rotavirus group A (RVA), norovirus genogroup II (GII), astrovirus, sapovirus, and adenovirus type F40/41 using realtime reverse transcription polymerase chain reaction. The proportions positive across the four years were compared using the chi-squared test statistic. Results One or more of the five virus targets were detected in 282 (32.4%) cases. A reduction in the positivity rate of RVA cases was observed from 2019 (12.1%, 95% confidence interval (CI) 8.7% to 16.2%) to 2020 (1.7%, 95% CI 0.2% to 6.0%; p < 0.001). However, in the 2022, RVA positivity rate rebounded to 23.5% (95% CI 18.2% to 29.4%). For norovirus GII, the positivity rate fluctuated over the four years with its highest positivity rate observed in 2020 (16.2%; 95% C.I, 10.0% to 24.1%). No astrovirus cases were detected in 2020 and 2021, but the positivity rate in 2022 was similar to that in 2019 (3.1% (95% CI 1.5% to 5.7%) vs 3.3% (95% CI 1.4% to 6.5%)). A higher case fatality rate was observed in 2021 (9.0%) compared to the 2019 (3.2%), 2020 (6.8%) and 2022 (2.1%) (p <0.001). Conclusion Our study finds that in 2020 the transmission of common enteric viruses, especially RVA and astrovirus, in Kilifi Kenya may have been disrupted due to the COVID_19 NPIs. After 2020, local enteric virus transmission patterns appeared to return to prepandemic levels coinciding with the removal of most of the government COVID_19 NPIs.

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Incident changes of rotavirus enteritis among children during the coronavirus disease-2019 pandemic in Hangzhou, China

Cited by 7 publications

References 7 publications

Risk Factors of Convulsions in Children With Rotavirus Gastroenteritis and Construction of a Nomogram Prediction Model

Risk Factors of Convulsions in Children With Rotavirus Gastroenteritis and Construction of a Nomogram Prediction Model

Gestational diabetes mellitus in the COVID‐19 pandemic: A retrospective study from Hangzhou, China

Temporal changes in the positivity rate of common enteric viruses among paediatric admissions in coastal Kenya, in the period spanning the COVID-19 pandemic, 2019-2022

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