Incidencia y patrones de transmisión de rubeola en México

Díaz-Ortega, José Luis; Meneses-Reyes, Carlos D.; Palacios-Martínez, Manuel

doi:10.1590/s0036-36342007000500004

Cited by 8 publications

(3 citation statements)

References 27 publications

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“…Results indicate that 97.1% of the pregnant women studied had protective (≥ 15 IU/mL) antibodies against rubella virus infection. In Mexico, vaccination against rubella started in 1998 [ 18 ]. Although the majority of pregnant women tested had protective antibodies, nearly 3% of women were susceptible to rubella.…”

Section: Discussionmentioning

confidence: 99%

Rubella Immune Status in Pregnant Women in a Northern Mexican City

et al. 2016

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BackgroundThe seroepidemiology of rubella virus infection in pregnant women in northern Mexico is largely unknown. We sought to determine the seroprevalence of rubella virus infection in pregnant women in the northern Mexican city of Durango, Mexico. Seroprevalence association with the socio-demographic, clinical and behavioral characteristics of the pregnant women was also investigated.MethodsThrough a cross-sectional study, we determined the seroprevalence of IgG and IgM anti-rubella virus in 279 pregnant women (mean age 29.17 ± 5.96 years; range 15 - 43 years) attending in a clinic of family medicine using enzyme-linked fluorescent assays. A questionnaire was used to obtain the socio-demographic, clinical and behavioral characteristics of the pregnant women. The association of rubella seropositivity and characteristics of the women was assessed by bivariate and multivariate analyses.ResultsAnti-rubella IgG antibodies (≥ 15 IU/mL) were found in 271 (97.1%) of the 279 pregnant women examined. None of the 279 pregnant women were positive for anti-rubella IgM antibodies. Multivariate analysis of socio-demographic, clinical and behavioral variables showed that seroreactivity to rubella virus was positively associated with national trips (OR = 7.39; 95% CI: 1.41 - 38.78; P = 0.01), and negatively associated with age (OR = 0.26; 95% CI: 0.06 - 0.99; P = 0.04).ConclusionsRate of rubella immunity in pregnant women in the northern Mexican city of Durango is high. However, nearly 3% of pregnant women are susceptible to rubella in our setting. Risk factors associated with rubella seropositivity found in this study may be useful for optimal design of preventive measures against rubella and its sequelae.

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Section: Discussionmentioning

confidence: 99%

Rubella Immune Status in Pregnant Women in a Northern Mexican City

et al. 2016

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“…Actions such as epidemiological alerts, virologic surveillance and intensification of preventive immunoprophylaxis were included. 36 As a result, few cases of congenital rubella infection have been officially reported since 2008, although there are sporadic reports due to active surveillance. 14,37 Our results further support the success of this program in our country and are consistent with those reported by Alvarado-Esquivel et al in Durango, Mexico.…”

Section: Discussionmentioning

confidence: 99%

Frequency of risk infections for congenital infection in pregnant women

et al. 2021

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BACKGROUND: TORCH and other infections can be vertically transmitted and provoke abortions or result in congenitally infected newborns. Most babies are born with subclinical infection but have a high risk of developing sequalae later. OBJECTIVE:To determine the frequency of seven endemic infections that represent risk for vertical transmission among pregnant women of a tertiary care hospital. MATERIALS AND METHODS:Prospective, cross-sectional study carried out in pregnant women attended at the INPer between 2010 and 2012. Infections were investigated by serological risk markers among pregnant women living in the Valley of Mexico and answered a questionnaire including risk factors. RESULTS:A total of 1079 pregnant women were studied, and the overall frequency of infection was 5.7%. Anti-Toxoplasma gondii low avidity IgG (2.0%) and parvovirus B19 IgM (2.0%) were the most common. No HBV S-Ag and one rubella case were detected. An association of markers studied with fetal malformations and transfusions (p < 0.015) was found. Toxoplasma infection was associated with the last two variables, as well as with the consumption of raw meat, previous positive TORCH and infection with HPV. Parvovirus B19 IgM was associated with stillbirths, and T. pallidum with HIV. Four cases had double infections. CONCLUSIONS:This study supports the success of vaccination control programs against rubella and active HBV, although infections or perinatal risk are still challenging for this group of women and their children´s health.

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“…22 This strategy reduced rubella incidence by more than 98%, and no CRS was reported since 2008 in Mexico and Costa Rica. 30,31 A universal or risk population approach to adults should also be considered in Vietnam and other countries, initiating a rubella elimination programme to protect WCBA directly and indirectly from exposure to rubella, depending on the feasibility of such approaches and the available resources.…”

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confidence: 99%

Rubella seroprevalence among mothers and incidence of congenital rubella three years after rubella vaccine introduction in Vietnam

Toizumi

Tanaka

Moriuchi

et al. 2021

Human Vaccines & Immunotherapeutics

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Following a rubella outbreak in 2011, Vietnam implemented a mass measles-rubella vaccination campaign for children aged 1-14 years in 2014-2015, further expanding the target age to 16-17 years in 2016; routine vaccination was introduced in 2014. However, there was concern that a substantial proportion of women of child-bearing age were still susceptible to rubella, with the fear of congenital rubella emergence. Thus, we conducted a prospective cohort study in Nha Trang, Vietnam, from 2017-2018 to investigate pregnant women's susceptibility to rubella infection, the incidence of congenital rubella infection, and factors associated with susceptibility. Cord blood was tested for rubella-specific immunoglobulin M (IgM) and IgG; neonatal saliva and cord blood specimens were examined for rubella-RNA. We analyzed 2013 mother-baby pairs. No baby was rubella-IgM or rubella-RNA positive. Overall, 20.4% of mothers were seronegative (95% confidence interval, 18.6%-22.1%). The seronegativity was significantly low among mothers aged <35 years. We found that maternal age groups of 20-24 and 25-29 years, and the lack of self-reported vaccination history were significantly associated with seronegativity. Many pregnant women who were not covered by the vaccination campaign are still at risk of rubella infection.

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Incidencia y patrones de transmisión de rubeola en México

Cited by 8 publications

References 27 publications

Rubella Immune Status in Pregnant Women in a Northern Mexican City

Rubella Immune Status in Pregnant Women in a Northern Mexican City

Frequency of risk infections for congenital infection in pregnant women

Rubella seroprevalence among mothers and incidence of congenital rubella three years after rubella vaccine introduction in Vietnam

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