Incidencia de las malarias gestacional, congénita y placentaria en Urabá (Antioquia, Colombia), 2005-2007

Abstract

Introducción: en Colombia se ignora la frecuencia de malarias gestacional (MG), congénita (MC) y placentaria (MP) y la mortalidad asociada a ellas, así como el cuadro clínico de la MG.Objetivos: calcular la prevalencia e incidencia de MG, MP y MC, la mortalidad por MG y MC, y describir y comparar entre mujeres con y sin MG, los síntomas, signos y las características de la MG.Metodología: estudio descriptivo con componente longitudinal (cohorte) y transversal, con gestantes de 15 a 44 años, sus placentas e hijos. Las gestantes se captaron en las consultas prenatales y salas de parto de tres municipios de Urabá (Antioquia, Colombia), entre 2005 y 2007.Resultados: se captaron 2117 gestantes: a) cohorte: n=1927 mujeres con mínimo dos exámenes de gota gruesa; b) grupo transversal: n=190 mujeres con solo un examen de gota gruesa (en consulta prenatal o en parto). Hubo 220 casos de MG. Según la gota gruesa para Plasmodium las frecuencias fueron: prevalencia MG: 10,39%; proporción de incidencia MG: 9,28%; tasa de incidencia de MG: 9,01 por 100 mujeres/semana; proporción MC: 2,7%; prevalencia de MP: 11,7%. P. vivax causó 76% de MG, P. falciparum 22%, ambas especies 2%. Los síntomas y signos hallados en las gestantes con MG concordaron con los referidos para gestantes y no gestantes. No hubo muertes entre las 220 gestantes que presentaron malaria ni entre los cinco niños que presentaron MC.Conclusiones: las frecuencias de MG, MC y MP indican que esas entidades son problemas de salud pública en la población de gestantes y neonatos de Urabá.

Malaria during pregnancy and newborns outcome in an unstable transmission area in Brazil: a population-based record linkage study

“…The number of studies estimating the real frequency of malaria in pregnant women is still limited, both in Brazil and in other regions of the Americas, which are considered low transmission areas 2 . The prevalence (8.9%) of malaria during pregnancy in our study was similar to the findings of a multi-centric study that enrolled data from the Americas (Guatemala, Colombia, and Brazil) between 2008-2011, and another study performed in Urubá (Colombia) between 2005-2009 24,25 . Though, the prevalence is higher in relation to reports from Iquitos (6.6%) (Peru), and from other Brazilian cities, such as Manaus (6.1%) and Coari (4.3%) in the Amazonas state, and Rio Branco (1.4%) in Acre state 26-29 .…”

An optimal control problem applied to malaria disease in Colombia

“…However, cases of congenital malaria have arisen and in addition the incidence of malaria has been concentrated mainly in specific sectors or communes of the municipality. This suggests that the dynamics of transmission is changing, which generates a new public health alert [5]. For this reason in this work, we define some control variables, and we formulate an optimal control problem defined by (3), (2) and (4).…”

Quantification of malaria antigens PfHRP2 and pLDH by quantitative suspension array technology in whole blood, dried blood spot and plasma

“…PfHRP2 and pLDH were measured in 765 plasma samples collected at three time points during pregnancy from [33]. Additionally, 75 plasma samples collected at three time points from 25 pregnant women never exposed to malaria, who attended the Hospital Clínic of Barcelona during pregnancy and delivery in 2010, were included in the assay as negative controls.…”