Incidência de Efeitos Adversos relacionados à Prednisona em Ensaios Clínicos Randomizados e Controlados com seguimento superior a um ano

Schafranski, Marcelo Derbli; Merlini, Alexandre Bueno; Trentini, Conrado Auer; Justus, Filipe Fernandes; Júnior, João Remí de Freitas

doi:10.15743/rbmi.2014.0007

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2016

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“…Thus, the prolonged use of glucocorticoids enables the appearance of fungus infections, bacteria, and viruses that may generate severe disseminated infections. [78] Indiscriminate use of antibiotics triggers and accelerates the defense mechanisms of bacteria, which by genetic mutations, they develop a resistance to these drugs, reducing their efficiency. This problem becomes relevant to public health since these drugs resistance happens at higher speeds than the development of new drugs.…”

Section: Discussionmentioning

confidence: 99%