Incidence, stability and risk assessment for sulfonamides and tetracyclines in aqua-cultured Nile Tilapia fish of Egypt

Abstract

Graphical abstract

Preliminary investigation on the occurrence and health risk assessment of antibiotics in cultured tilapia retailed at a commercial outlet in Tema, Ghana

“…The findings of the current study showed that TCs (with high detection frequencies of 58.3% and 62.5%) were often used by farmers to monitor fish health and treat diseases, without adhering to the recommended withdrawal period for these antibiotics. Additionally, in some cases, the reason for high levels of tetracycline antibiotics in fish samples could be the use of substances containing antibiotics, like poultry manure, to improve plankton growth in aquaculture systems [ 43 ]. The maximum residual limits (MRL) of 100 μg/kg established by the European Commission [ 14 ] were not exceeded in any of the present study's tilapia samples that were contaminated with TCs.…”

“…The data in Table 3 demonstrated that SA, including the SMX, was below the limit of quantification (<LOQ) in the samples from the retail centre. [ 43 ] found SMX in tilapia in El-Fayoum in another Egyptian study, with a mean concentration of 52.41 μg/kg. In a study conducted by Ref.…”

“…The estimated daily intakes (EDI) for every antibiotic under study were found to be significantly lower than the acceptable daily intakes (ADI). Similarly, the estimated daily intake (EDI) derived from the average daily fish consumption in Egypt was determined to be lower than the acceptable daily intake values established by the World Health Organization [ 43 ]. Additionally, a recent study conducted in Argentina on fish revealed that the estimated dietary exposure to multiantibiotic residues in commercial fish did not surpass the acceptable daily intake [ 16 ].…”

Pharmacokinetic behaviour and pharmacokinetic–pharmacodynamic integration of doxycycline in rainbow trout (Oncorhynchus mykiss) after intravascular, intramuscular and oral administrations

“…Tetracyclines, which have a bacteriostatic effect by inhibiting the protein synthesis of bacteria, are one of the most widely used antibiotic groups for therapeutic and prophylactic purposes in aquaculture (Ahmed et al., 2020; Morshdy et al., 2022). Doxycycline (DO), a second‐generation, semi‐synthetic tetracycline derivative antibacterial drug, has a broad‐spectrum bacteriostatic activity against a wide range of gram‐positive and gram‐negative bacteria as well as many protozoa (Bilen & Elbeshti, 2019; del Castillo, 2013; Holmes & Charles, 2009).…”

Tilapia Fish Farming Assessment using Water Wells in Fayoum and Egypt: Case Study

“…Fish farming possesses a major share for Egypt agriculture income [1], as well as a vital source of income for people living along the coast and the Nile River, in addition to the fisheries in the canals, river Nile, lakes, ponds, Mediterranean Sea, and Red Sea that are considered other key activities in the country. Despite this, the country's gross domestic product is dominated by fisheries, it also contributes to foreign exchange revenues by exporting [2].…”