Incidence, Risk Factors and Anatomy of Peripersonal Visuospatial Neglect in Acute Stroke

Abstract

Aim: The study aims to describe the epidemiology and the neural correlates of peripersonal visuospatial neglect (PVN) in patients admitted to the Geneva Stroke Unit for an acute stroke or a transient ischemic attack (TIA). Methods: Eligible subjects were tested for PVN using both the Ota's discriminative cancellation task and a line bisection task. Brain lesions were identified on diffusion-weighted imaging. A multivariate analysis was performed to identify risk factors of PVN. Results: Ninety-eight consecutive patients (40.8% females) were recruited: 64 cases of ischemic stroke, 9 cases of hemorrhagic stroke and 25 cases of TIAs. The mean age was 61.9 ± 2.86 years. The incidence of PVN was 23.5% (95% CI 15.5-33.1) and was not significantly different between patients with right and left hemisphere stroke. There were 5 cases of ipsilesional neglect. There was no association between PVN and age, sex, stroke severity, handedness, lesion type, lesion volume and time to first examination. Lesions of temporal and parietal lobes were the most frequent in patients with PVN. Conclusion: PVN has a low incidence in the acute stroke settings and there is no particular predictor of its presence. It is most often associated with temporo-parietal lesions.

An exploratory cohort study of sensory extinction in acute stroke: prevalence, risk factors, and time course

“…The study procedure has been described previously (Kamtchum Tatuene et al 2016). Briefly, exclusion criteria were past history of stroke, severe aphasia, and severe stroke (NIHSS score >20); and any documented alteration of visual, tactile, auditory, or cognitive functions susceptible to interfere with the neuropsychological evaluation.…”

“…The description of the location of brain lesions was done using region-involvement indices as reported previously (Kamtchum Tatuene et al 2016). The following functional regions of the brain were attributed a score of 1 if they were partially or totally affected by the acute stroke or 0 if not involved at all: frontal, insular, rolandic, parietal, temporal, occipital, thalamic, caudate nucleus, putamen, pallidum, internal capsule, brain stem, and cerebellum.…”

Dynamics of clinical and neurological changes in patients with acute ischemic stroke in an open clinical study

“…One-sided spatial neglect is a violation of perception, attention, and action in the space opposite to the affected hemisphere of the brain (usually in the left). Neglect occurs in most patients with stroke, causing damage to the temporoparietal sections ( 32 ). Prismatic adaptation is a method in which the plasticity of sensorimotor functions is stimulated by manipulation with sensorimotor relationships.…”

Rehabilitation in acute stroke from the point of view of evidence-based medicine: possibilities of drug treatment

“…К о р р е к ц и я с и н д р о м а п р о с т р а н с т в е н н о г о и г н о р и р о в а н и я ( н е г л е к т а ) Односторонний пространственный неглект -расстройство восприятия, внимания и действия в пространстве, противоположном пораженному полушарию головного мозга (как правило, в левом). Неглект наблюдается более чем у половины пациентов с инсультом, и наиболее часто к его развитию приводит поражение височно-теменных отделов [23]. Для неглекта характерна высокая частота спонтанного восстановления, тем не менее его наличие повышает риск падений, увеличивает сроки лечения в стационаре и, главное, препятствует восстановлению движения в паретичных конечностях, равновесия и мобильности [24].…”