Incidence rates of occupational diseases in the Dutch construction sector, 2010–2014: Table 1

Molen, Henk F. van der; Vries, Sanne C de; Stocks, Susan Jill; Warning, Jan; Frings‐Dresen, Monique H. W.

doi:10.1136/oemed-2015-103429

Cited by 33 publications

(21 citation statements)

References 13 publications

(17 reference statements)

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“…Among individuals with chronic tinnitus, hearing thresholds were significantly worse in patients in the HIGH-RISK group compared to those in the LOW-RISK group. This finding is in accordance with the literature [ 3 , 4 , 5 , 34 , 35 , 36 , 37 , 38 , 39 , 41 , 42 , 43 , 44 , 45 , 47 , 48 , 49 , 50 , 51 , 54 , 55 , 56 , 57 , 58 , 68 , 70 , 74 , 88 ]. Our results showed a worse, although not significant, hearing threshold for high frequencies in the left ear compared to the right among individuals in the HIGH-RISK group; no side difference was found in the LOW-RISK group.…”

Section: Discussionsupporting

confidence: 94%

Work-Related Noise Exposure in a Cohort of Patients with Chronic Tinnitus: Analysis of Demographic and Audiological Characteristics

Ralli

Balla

Greco

et al. 2017

IJERPH

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Work-related noise exposure is one of the major factors contributing to the development of adult-onset hearing loss and tinnitus. The aim of this study was to analyze, in patients with chronic tinnitus and long-term occupational noise exposure, (A) characteristics of hearing loss, tinnitus, comorbidities, demographic characteristics and a history of work-related noise exposure and (B) differences among individuals employed in occupations with high and low risk of developing work-related noise-induced hearing loss (NIHL). One hundred thirty six patients with chronic tinnitus and at least a 10 year-long working history were divided into two groups based on the risk of their profession to induce NIHL. Individuals employed in jobs at high risk for NIHL were mostly males and exhibited a poorer hearing threshold, more evident in the left ear. Tinnitus was mostly bilateral; the next largest presentation was left-sided; patients described their tinnitus as buzzing or high-pitched. Correlation between age, length of tinnitus and worse hearing was found. Patients with a higher degree of hearing impairment were mostly males and were more likely to have a family history of hearing loss and at least one cardiovascular comorbidity. Our study shows some differences in individuals with tinnitus and a history of a profession associated with increased exposure to NIHL compared to those without such a history.

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Section: Discussionsupporting

confidence: 94%

Work-Related Noise Exposure in a Cohort of Patients with Chronic Tinnitus: Analysis of Demographic and Audiological Characteristics

Ralli

Balla

Greco

et al. 2017

IJERPH

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“…Occupational noise-induced hearing loss (ONIHL), characterized by auditory function impairments after long-term and persistent exposure to excessive noise, is a common occupational disease ( 1 , 2 ). According to a recent systematic review, the prevalence of ONIHL in noise-exposed workers ranges from 7 to 21% ( 3 ).…”

Section: Introductionmentioning

confidence: 99%

Analysis of serum microRNA expression in male workers with occupational noise-induced hearing loss

Yang

Yan

et al. 2018

Braz J Med Biol Res

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Occupational noise-induced hearing loss (ONIHL) is a prevalent occupational disorder that impairs auditory function in workers exposed to prolonged noise. However, serum microRNA expression in ONIHL subjects has not yet been studied. We aimed to compare the serum microRNA expression profiles in male workers of ONIHL subjects and controls. MicroRNA microarray analysis revealed that four serum microRNAs were differentially expressed between controls (n=3) and ONIHL subjects (n=3). Among these microRNAs, three were upregulated (hsa-miR-3162-5p, hsa-miR-4484, hsa-miR-1229-5p) and one was downregulated (hsa-miR-4652-3p) in the ONIHL group (fold change >1.5 and Pbon value <0.05). Real time quantitative PCR was conducted for validation of the microRNA expression. Significantly increased serum levels of miR-1229-5p were found in ONIHL subjects compared to controls (n=10 for each group; P<0.05). A total of 659 (27.0%) genes were predicted as the target genes of miR-1229-5p. These genes were involved in various pathways, such as mitogen-activated protein kinase (MAPK) signaling pathway. Overexpression of miR-1229-5p dramatically inhibited the luciferase activity of 3′ UTR segment of MAPK1 (P<0.01). Compared to the negative control, HEK293T cells expressing miR-1229-5p mimics showed a significant decline in mRNA levels of MAPK1 (P<0.05). This preliminary study indicated that serum miR-1229-5p was significantly elevated in ONIHL subjects. Increased miR-1229-5p may participate in the pathogenesis of ONIHL through repressing MAPK1 signaling.

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“…High-frequency hearing loss (HFHL), caused by excessive exposure to noise in the workplace, also known as noise-induced hearing loss (NIHL), is an important public health problem worldwide (May 2000 ; Sliwinska-Kowalska and Davis 2012 ). In the Dutch construction industry, it is one of the most commonly reported occupational diseases (van der Molen et al 2016 ). Therefore, secondary prevention (i.e., early identification) of HFHL by screening is of great importance, and stimulates to take actions to prevent progression of the hearing loss (Meyer-Bisch 1996 ).…”

Section: Introductionmentioning

confidence: 99%

Accuracy of an internet-based speech-in-noise hearing screening test for high-frequency hearing loss: incorporating automatic conditional rescreening

Rashid

Dreschler

2018

Int Arch Occup Environ Health

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PurposeTo validate the accuracy of an internet-based speech-in-noise hearing screening test for high-frequency hearing loss (HFHL) ‘Occupational Earcheck (OEC)’ incorporating an automatic conditional rescreening, in an occupationally noise-exposed population. Secondary objectives were to assess the effects of age on test accuracy measures, and to assess the test accuracy for different degrees of HFHL.MethodsA study was conducted on cross-sectional data of occupational audiometric examinations, including the index test OEC and reference standard pure-tone air conduction audiometry, of 80 noise-exposed workers. Sensitivity, specificity, and likelihood ratios were calculated for the OEC, after automatic conditional rescreening, for a younger and an older age group, and for two degrees of HFHL (HFHL25: PTA3,4,6 ≥ 25 dB HL, and HFHL35: PTA3,4,6 ≥ 35 dB HL, both for at least one ear).ResultsTest specificity for HFHL25 after a single test was 63%, and improved to 93% after the automatic conditional rescreen. Test sensitivity for HFHL25 decreased from 65% to 59%. Test sensitivity and specificity including automatic conditional rescreening for HFHL35 was 94% and 90%, respectively. The positive likelihood ratio for HFHL25 was 8.4, and for HFHL35 9.4. The negative likelihood ratio for HFHL35 was below 0.1.ConclusionsThe OEC is an appropriate screening test, especially for HFHL35. Normal-hearing workers who obtained a positive test result for the first test for one or two ears, benefit from having an automatic rescreen, resulting in an improvement of the test specificity, and hence prevent unnecessary referral.

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Incidence rates of occupational diseases in the Dutch construction sector, 2010–2014: Table 1

Cited by 33 publications

References 13 publications

Work-Related Noise Exposure in a Cohort of Patients with Chronic Tinnitus: Analysis of Demographic and Audiological Characteristics

Work-Related Noise Exposure in a Cohort of Patients with Chronic Tinnitus: Analysis of Demographic and Audiological Characteristics

Analysis of serum microRNA expression in male workers with occupational noise-induced hearing loss

Accuracy of an internet-based speech-in-noise hearing screening test for high-frequency hearing loss: incorporating automatic conditional rescreening

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