Incidence, Predictors, and Outcomes of Permanent Pacemaker Implantation Following Transcatheter Aortic Valve Replacement

Abstract

Early PPM implantation is a common complication following TAVR, and it is associated with higher mortality and a composite of mortality or heart failure admission at 1 year.

The interplay between permanent pacemaker implantation and mortality in patients treated by transcatheter aortic valve implantation: A systematic review and meta‐analysis

“…Firstly, the presence of a pre‐existing PPM could be a marker of increased patient risk. In fact, in studies reporting baseline characteristic of patients with and without pre‐existing PPM , subjects with permanent pacing before the procedure had higher rate of risk factors such as diabetes and prior myocardial infarction, lower left ventricular ejection fraction (EF) and higher EuroSCORE (Supporting Information Table 5). This might explain why this finding was mostly observed in patients undergoing trans‐apical approach.…”

In‐hospital outcomes of transcatheter versus surgical aortic valve replacement in end stage renal disease

“…The CoreValve high risk pivotal trial reported a PPM implantation rate of 19.8% in patients undergoing TAVR and 7.1% in patients undergoing SAVR ( P < 0.001) . Likewise, in a recent review of the Society of Thoracic Surgeons/American College of Cardiology TVT registry, the reported PPM implantation rate within 30‐days of TAVR was 6.7% with significantly more among those receiving self‐expanding valves (25.1%) versus balloon‐expanding valves (4.3%) .…”

Association of Clinical and Economic Outcomes With Permanent Pacemaker Implantation After Transcatheter Aortic Valve Replacement

“…22 These 1-year adverse outcomes were also seen by Fadahunsi and colleagues in an analysis of 9785 patients in the US Transcatheter Valve Therapy registry. 44 However, it is difficult to draw comparisons with the available data, given the different prostheses and periods in addition to the relatively short follow-up periods.…”