Incidence, Predictors, and Impact on Six-Month Mortality of Three Different Definitions of Contrast-Induced Acute Kidney Injury After Coronary Angiography

Guillon, Benoı̂t; Ecarnot, Fiona; Marcucci, Charles G.; Ducloux, Didier; Chatot, Marion; Badoz, Marc; Bonnet, Benjamin; Chopard, Romain; Frey, Pierre; Meneveau, Nicolas; Schiele, François

doi:10.1016/j.amjcard.2017.12.029

Cited by 22 publications

(28 citation statements)

References 21 publications

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“…Consistent with prior studies, AKI was associated with increased odds of 30‐day and 90‐day readmission and in‐hospital mortality as well as prolonged hospital length of stay in both inpatient and outpatient sample after adjusting for known confounders 3,7–9,16,28 . As a result, the overall economic burden of AKI to acute care hospitals during the study period was estimated to be $1.67 billion.…”

Section: Discussionsupporting

confidence: 78%

“…Consistent with prior studies, AKI was associated with increased odds of 30-day and 90-day readmission and in-hospital mortality as well as prolonged hospital length of stay in both inpatient and outpatient sample after adjusting for known confounders. 3,[7][8][9]16,28 As a result, the overall economic burden of AKI to acute care hospitals during the study period was estimated to be $1.67 billion. In addition, a higher percentage of AKI patients were discharged to long-term care facilities or transferred to another acute care facility than non-AKI patients-extending out the potential costs beyond the index event.…”

Section: An Analysis By Tsai Et Al Of Nationalmentioning

confidence: 99%

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Contemporary trend of acute kidney injury incidence and incremental costs among US patients undergoing percutaneous coronary procedures

Prasad

Rosenthal

Kartashov

et al. 2020

Cathet Cardio Intervent

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Objectives: To assess national trends of acute kidney injury (AKI) incidence, incremental costs, risk factors, and readmissions among patients undergoing coronary angiography (CAG) and/or percutaneous coronary intervention (PCI) during 2012-2017. Background: AKI remains a serious complication for patients undergoing CAG/PCI. Evidence is lacking in contemporary AKI trends and its impact on hospital resource utilization. Methods: Patients who underwent CAG/PCI procedures in 749 hospitals were identified from Premier Healthcare Database. AKI was defined by ICD-9/10 diagnosis codes (584.9/N17.9, 583.89/N14.1, 583.9/N05.9, E947.8/T50.8X5) during 7 days post index procedure. Multivariable regression models were used to adjust for confounders. Results: Among 2,763,681 patients, AKI incidence increased from 6.0 to 8.4% or 14% per year in overall patients; from 18.0 to 28.4% in those with chronic kidney disease (CKD) and from 2.4 to 4.2% in those without CKD (all p < .001). Significant risk factors for AKI included older age, being uninsured, inpatient procedures, CKD, anemia, and diabetes (all p < .001). AKI was associated with higher 30-day in-hospital mortality (OR adjusted = 2.55; 95% CI: 2.40, 2.70) and readmission risk

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Section: Discussionsupporting

confidence: 78%

Section: An Analysis By Tsai Et Al Of Nationalmentioning

confidence: 99%

Contemporary trend of acute kidney injury incidence and incremental costs among US patients undergoing percutaneous coronary procedures

Prasad

Rosenthal

Kartashov

et al. 2020

Cathet Cardio Intervent

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“…Here, AKI was defined as an absolute increase in serum creatinine of >0.5 mg/dL (44 mmol/L) or 0.3mg/dL (27 mmol/L), in line with most of the studies above. In this recent study, mortality risk was predicted based on the AKI definition used [ 38 ]. A recent single-center retrospective study involving over 4000 patients failed to demonstrate an association between CI-AKI and angiographic approach, despite adjusting for confounders [ 39 ].…”

Section: Radial Versus Femoral Access In Coronary Artery Disease (Cadmentioning

confidence: 99%

Acute Kidney Injury Post Cardiac Catheterization: Does Vascular Access Route Matter?

Ram

Horn

et al. 2019

CCR

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Background: Acute Kidney Injury as a complication of cardiac catheterization is associated with increased length of hospital stay and mortality. In recent years, the use of the radial artery for cardiac catheterization is increasing in frequency. </P><P> Objective: The objective of this concise review was to evaluate the method of cardiac access site and its impact on Acute Kidney Injury following cardiac catheterization. Methods: After a thorough search on Medline, Google Scholar and PubMed, we included all the literature relevant to Acute kidney injury following transradial and transfemoral cardiac catheterization. Results: While acute kidney injury was caused due to a variety of reasons, it was important to consider each case on an individual basis. We found a trend towards increased use of transradial approach in patients at high risk of developing kidney injury. However, limitations such as operator experience, anatomical challenges and so on do exist with this approach. Conclusion: Transradial access offers several advantages to a patient at high risk of acute kidney injury undergoing cardiac catheterization. Further large studies are needed to establish this trend in the years ahead.

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“…It is defined as an increase in SCr by 0.5 mg/dl or 25% within 72 h after using a contrast agent, which has also been confirmed in many clinical studies. In fact, the incidence and prognostic value of CA-AKI are different with different definitions [4][5][6][7][8]. It has been found that different definitions have different efficacies in predicting long-term mortality in STEMI patients, and the criteria of the Acute Kidney Injury Network (AKIN) has better efficacy [4].…”

Section: Introductionmentioning

confidence: 99%

A comparison between two different definitions of contrast-associated acute kidney injury for long-term mortality in patients with diabetes undergoing coronary angiography: a prospective cohort study

Lun

Zhou

et al. 2020

BMC Cardiovasc Disord

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Background The definitions of contrast-associated acute kidney injury (CA-AKI) are diverse and have different predictive effects for prognosis, which are adverse for clinical practice. Few articles have discussed the relationship between these definitions and long-term prognosis in patients with diabetes. Methods A total of 1154 diabetic patients who were undergoing coronary angiography (CAG) were included in this study. Two definitions of CA-AKI were used: CA-AKIA was defined as an increase ≥ 0.3 mg/dl or > 50% in serum creatinine (SCr) from baseline within 72 h after CAG, and CA-AKIB was defined as an increase ≥ 0.5 mg/dl or > 25% in SCr from baseline within 72 h after CAG. We used Cox regression to evaluate the association of these two CA-AKI definitions with long-term mortality and calculate the population attributable risks (PARs) of different definitions for long-term prognosis. Results During the median follow-up period of 7.4 (6.2–8.2) years, the overall long-term mortality was 18.84%, and the long-term mortality in patients with CA-AKI according to both CA-AKIA and CA-AKIB criteria were 36.73% and 28.86%, respectively. We found that CA-AKIA (HR: 2.349, 95% CI 1.570–3.517, p = 0.001) and CA-AKIB (HR: 1.608, 95% CI 1.106–2.339, p = 0.013) were associated with long-term mortality. The PARs were the highest for CA-AKIA (31.14%), followed by CA-AKIB (14.93%). Conclusions CA-AKI is a common complication in diabetic patients receiving CAG. The two CA-AKI definitions are significantly associated with a poor long-term prognosis, and CA-AKIA, with the highest PAR, needs more clinical attention.

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Incidence, Predictors, and Impact on Six-Month Mortality of Three Different Definitions of Contrast-Induced Acute Kidney Injury After Coronary Angiography

Cited by 22 publications

References 21 publications

Contemporary trend of acute kidney injury incidence and incremental costs among US patients undergoing percutaneous coronary procedures

Contemporary trend of acute kidney injury incidence and incremental costs among US patients undergoing percutaneous coronary procedures

Acute Kidney Injury Post Cardiac Catheterization: Does Vascular Access Route Matter?

A comparison between two different definitions of contrast-associated acute kidney injury for long-term mortality in patients with diabetes undergoing coronary angiography: a prospective cohort study

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