Incidence of synchronous and metachronous colorectal carcinoma

Cunliffe, W. J.; Hasleton, Philip; Tweedle, D. E. F.; Schofield, Philip F.

doi:10.1002/bjs.1800711210

“…[7][8][9][10][11][12][13] Interestingly, when compared by stage, no statistically significant difference has been found in the overall and disease-free survival between synchronous and primary cancers.…”

Section: Introductionmentioning

confidence: 99%

Synchronous colonic malignancy

Hake

¹

,

Umale

²

,

Yadgire

³

et al. 2016

Int J Res Med Sci

0

View full text Add to dashboard Cite

“…5,6 There are 2 important problems regarding the preoperative evaluation of obstructive colorectal cancer: synchronous colon cancer and liver metastasis. The incidence of synchronous colon cancers in patients diagnosed with colorectal cancer has been reported to be 2% to 10.7%, 7,8 and synchronous liver metastasis has been identified in 20%-30% of patients with primary colorectal cancers.9,10 The preoperative evaluation of the total colon to the proximal part of the obstruction and systemic evaluation using computed tomography (CT) scanning and magnetic resonance imaging (MRI) are thus important to determine the extent of surgical resection.Since Dohmoto 11 first reported metallic colon stent placement in 1991, the self-expandable metallic stent (SEMS) has been widely applied as a palliative management for obstructive colorectal cancer. In June 2014, we started SEMS placement as a bridge to surgery for patients with obstructive colon cancer and performed the curative resection after SEMS placement.…”

mentioning

confidence: 99%

“…5,6 There are 2 important problems regarding the preoperative evaluation of obstructive colorectal cancer: synchronous colon cancer and liver metastasis. The incidence of synchronous colon cancers in patients diagnosed with colorectal cancer has been reported to be 2% to 10.7%, 7,8 and synchronous liver metastasis has been identified in 20%-30% of patients with primary colorectal cancers.…”

mentioning

confidence: 99%

“…5,6 There are 2 important problems regarding the preoperative evaluation of obstructive colorectal cancer: synchronous colon cancer and liver metastasis. The incidence of synchronous colon cancers in patients diagnosed with colorectal cancer has been reported to be 2% to 10.7%, 7,8 and synchronous liver metastasis has been identified in 20%-30% of patients with primary colorectal cancers. 9,10 The preoperative evaluation of the total colon to the proximal part of the obstruction and systemic evaluation using computed tomography (CT) scanning and magnetic resonance imaging (MRI) are thus important to determine the extent of surgical resection.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Elective Surgery After Endoscopic Self-Expandable Metallic Stent Placement for Patients With Obstructive Colon Cancer: Preoperative Systemic Evaluation and Management

Matsushima

¹

,

Adachi

²

,

Hamada

³

et al. 2017

International Surgery

1

0

View full text Add to dashboard Cite

One-stage curative surgical resection for obstructive colon cancer is challenging. Selfexpandable metallic stents (SEMSs) are known as an alternative treatment used to avoid emergency operation. We aimed to evaluate the significance of SEMS placement as a bridge to surgery and the surgical outcomes of the elective operation. A consecutive 20 patients with obstructive colon cancer undergoing SEMS placement between June 2014 and February 2016 were included. The technical outcomes of the SEMS placement, surgical procedures, and surgical outcomes were evaluated retrospectively. Among them, 2 patients were treated with a SEMS palliatively, and the others were treated with a SEMS as a bridge to surgery. All SEMS were placed successfully at the first attempt, and there was no SEMS-related complication. Before surgery, all patients could be diagnosed histologically, and they were evaluated systemically including proximal colon or distant metastasis. The median time to operation after SEMS placement was 14 days (range 9-20Corresponding author: Hajime Matsushima, Department of Surgery, Nagasaki Rosai Hospital, 2-12-5 Setogoshi, Sasebo, 857-0134, Japan.Tel.: 81-956-49-219181-956-49- , Fax: 81-956-49-2358 E-mail: h.matsushima.1020@gmail.com Int Surg 2017;102 21 days). Seven of the 18 patients underwent a laparoscopic colectomy without conversion to laparotomy. All patients with stage II or III colon cancer underwent curative surgery, and 2 patients with stage IV colon cancer underwent a one-stage resection of the primary colon cancer and simultaneous liver metastasis after the evaluation of hepatic functional reserve. There was no mortality or SEMS-related complication in the perioperative period. SEMS placement as a bridge to surgery for patients with obstructive colon cancer is safe and effective to provide an adequate amount of time for a preoperative systemic management and evaluation.Key words: Colorectal cancer -Malignant colonic obstruction -Self-expandable metallic stent -Bridge to surgery -Palliation C olorectal cancer is a common malignancy, and more than 1 million cases are diagnosed annually worldwide.1 Although the use of screening programs has spread, 8%-29% of colorectal cancer patients are diagnosed in emergency status due to a large bowel obstruction.2,3 The treatment for obstructive colorectal cancer is still controversial. 4Emergency operations such as Hartman's procedure and colostomy have conventionally been performed for patients with obstructive colorectal cancer, but high mortality and morbidity rates remain for this malignancy. 5,6 There are 2 important problems regarding the preoperative evaluation of obstructive colorectal cancer: synchronous colon cancer and liver metastasis. The incidence of synchronous colon cancers in patients diagnosed with colorectal cancer has been reported to be 2% to 10.7%, 7,8 and synchronous liver metastasis has been identified in 20%-30% of patients with primary colorectal cancers.9,10 The preoperative evaluation of the total colon to the proximal part of the obstru...

show abstract

“…Most patients with SCRCs present with two concurrent lesions. Th e incidence of SCRCs among colorectal cancers ranges from 2% to 11% in recent publications (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14) ( Table ). Th e presence of three or more SCRCs has only rarely been reported.…”

mentioning

confidence: 99%

Synchronous Trifocal Colorectal Cancer

Charalampoudis

¹

,

Sotiropoulos

²

,

Kykalos

³

et al. 2016

Baylor University Medical Center Proceedings

0

View full text Add to dashboard Cite

Synchronous colorectal cancers (SCRCs) have been increasingly diagnosed due to emerging diagnostic modalities. The presence of three or more synchronous colorectal cancers has, however, only rarely been reported. A 76-year-old white man presented for management of two concurrent colorectal adenocarcinomas in the left colon evidenced on total colonoscopy. Preoperative abdominal ultrasonography and thoracoabdominal computed tomography were negative for metastatic disease. The patient underwent an elective left hemicolectomy. The pathology report ultimately showed the presence of three moderately differentiated, distinct colorectal cancers. The patient experienced an uneventful recovery.A lthough uncommon, synchronous colorectal cancers (SCRCs) have been increasingly diagnosed due to emerging diagnostic modalities. Most patients with SCRCs present with two concurrent lesions. Th e incidence of SCRCs among colorectal cancers ranges from 2% to 11% in recent publications ( 1-14 ) ( Table ). Th e presence of three or more SCRCs has only rarely been reported. CASE PRESENTATIONA 76-year-old white man presented for management of two concurrent colorectal adenocarcinomas in the left colon (one near the splenic fl exure and one in the sigmoid colon), evidenced on total colonoscopy performed due to change of bowel habits and intermittent rectal bleeding during the past 2 months. A third polypoid lesion was encountered between these two lesions; it showed benign macroscopic features and had therefore not been biopsied. Th e colon proximal to the splenic fl exure was free of lesions. Th e patient had undergone no screening colonoscopy in the past, and his family history was negative for colorectal adenomas/cancer or hereditary nonpolyposis colorectal cancer-associated tumors. He had arterial hypertension under medication and had had a radical prostatectomy for prostate cancer 10 years earlier. Preoperative abdominal ultrasonography and thoracoabdominal computed tomography were negative for metastatic disease. Th e patient underwent an elective left hemicolectomy with a transverserectal anastomosis. Th e histological study showed the presence of three moderately diff erentiated, distinct colorectal cancers:

show abstract

Incidence of synchronous and metachronous colorectal carcinoma

Cited by 154 publications

References 16 publications

Synchronous colonic malignancy

Synchronous colonic malignancy

Elective Surgery After Endoscopic Self-Expandable Metallic Stent Placement for Patients With Obstructive Colon Cancer: Preoperative Systemic Evaluation and Management

Synchronous Trifocal Colorectal Cancer

Contact Info

Product

Resources

About