Incidence of sudden cardiac death, myocardial infarction and far- and near-transyears

Halberg, Franz; Cornélissen, Germaine; Otsuka, Kuniaki; Fišer, Bohumil; Mitsutake, G.; Wendt, H.; Johnson, Pamela Jo; Gigolashvili, M. Sh.; Бреус, Т. К.; Sonkowsky, Robert P.; Чибисов, С. М.; Katinas, George; Siègelovà, Jarmila; Dušek, Jiří; Singh, Ram B.; Berri, B.L.; Schwartzkopff, Othild

doi:10.1016/s0753-3322(05)80039-3

Cited by 25 publications

(16 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The nonphotic components were also associated with SCD [59]. Cardiac arrest occurs due to a acute precipitating trigger and the chronic electrical instability of the myocardium.…”

Section: Mechanisms Underlying Sudden Cardiac Deathmentioning

confidence: 99%

Nutrition in Chronocardiology: We are Indebted Professor Franz Halberg

Singh¹

2012

TONUTRAJ

View full text Add to dashboard Cite

Abstract:Franz Halberg had very many experiences in India. The word circadian and chronobiology, chronocardiology and chronoastrobiology were coined by him. He also discovered that in studies of single daily meals, eating breakfast was associated with weight loss compared to dinner, despite similar energy intake. The role of time-adjusted drug intake, especially in the early morning, was also known to ancient Indian physicians. In Ayurveda, drinking of large amounts of water in the early morning is advised, which appears to be in an attempt to increase vagal tone due to gastric distention. A circadian cell cycle resides in every cell, and peripheral timing mechanisms are being documented in molecular biologic terms at about 24-hour (circadian) and higher (ultradian) frequencies, with coordination, in mammals, by the adrenal and the pineal-hypothalamic-pituitary network. The suprachiasmatic nuclei (SCN) and clock gene contribute to the coordination of the circadian rhythms' phase and amplitude, in every day life. The SCN are influenced by the daily alternation between light and darkness directly via the eyes and by plasma melatonin concentrations secreted by the pineal gland, which is a window to both light and geomagnetics. A clinical event occurs when our neuroendocrine time structures (chronomes) are not able to cope with the adverse effects of stimuli from within or from without, acting, e.g., via the sympathetic nervous system. Triggering of the neuroendocrines by environmental factors may activate the pineal gland, pituitary functions and adrenal secretions, resulting in adverse effects on circadian variations, heart rate variability (HRV) and blood pressure variability (BPV). Circadian rhythm was known to ancient man from the time of Homoerectus and Homosapiens who use to have intercourse in the early morning hours, before going for hunting to forests, causing increased secretion of testosterone in the morning as a circadian rhythm. Frey considered the mean distribution of deaths along the scales of the day and the year. In one industrial population, Pell and D'Allonzo, discussed time-macroscopically the occurrence of a peak in the morning hours in a study of acute myocardial infarction (AMI), a proposition also ascertained and extended to the yearly pattern time-microscopically. The subsequent reports from other countries, the erstwhile Soviet Union and the extensive data by WHO in the report of myocardial infarction Community Registers from 19 European centers demonstrated a peak incidence of onset of chest pain due to AMI from 8.00 to 11.00 AM with a ratio of 1:2, approximately. In one study from India, in 605 AMI patients, 39% of those who had Q wave infarction (n=174) had the onset between 6.00 AM to 12.00 noon. A further study from India, among 202 AMI patients, the incidence of onset of chest pain was highest in the second quarter of the day (41.0%), mainly between 4-8 a.m., followed by the 4 th quarter, usually after large meals (28.2%). Emotion was the second most common trigger (43.5%), which was...

show abstract

“…The nonphotic components were also associated with SCD [59]. Cardiac arrest occurs due to a acute precipitating trigger and the chronic electrical instability of the myocardium.…”

Section: Mechanisms Underlying Sudden Cardiac Deathmentioning

confidence: 99%

Nutrition in Chronocardiology: We are Indebted Professor Franz Halberg

Singh¹

2012

TONUTRAJ

View full text Add to dashboard Cite

show abstract

“…Transyears have already been described in a unique 15-year data series of breakdown products of the steroids of the gonads and the adrenal cortex, namely the daily urinary excretion of 17-ketosteroids by a clinically healthy man [28,29]. Transyears may also characterize the adrenal medulla and the sympathetic nervous system and the blood pressure via which these structures in space coordinate emotions and behavior in time at all levels of organization [30]. Components with periods of 1 year and slightly longer than 1 year may constitute more than one 'seasonal' order.…”

Section: Discussionmentioning

confidence: 99%

Plasma catecholamines: follow-up on 10-year study in health and cardiovascular disease

Prikryl¹,

Cornélissen²,

Otsuka³

et al. 2005

Biomedicine & Pharmacotherapy

Self Cite

View full text Add to dashboard Cite

The predictive value of blood pressure (BP), heart rate (HR), and catecholamines in terms of any subsequent development of cardiovascular disease was investigated. Systolic (S) and diastolic (D) BP, HR, epinephrine (E) and norepinephrine (NE) were measured three times a year in 1980, 1984, and 1989 on 20 clinically healthy subjects, 18 patients with 'essential hypertension', and 22 patients with angina pectoris. Of the 22 patients in the latter group, 15 died during a 2-year follow-up (1990)(1991). Each individual data series was analyzed by single cosinor to assess the circannual variation. Results were summarized by population-mean cosinor for each group. Parameter tests were used to compare the circannual rhythm characteristics among the different patient groups. A circannual rhythm was invariably demonstrated on a group basis (P < 0.05). Differences in MESOR and/or circannual amplitude were found among the different groups. In particular, patients with angina pectoris who will die within the 2-year follow-up differ in terms of their E and NE from all other patient groups, a difference already detected at the beginning of the study, more than 10 years before they die. A similar separation is not achieved in terms of BP or HR.

show abstract

“…periods between 1 and 3 years (e.g. Mavromichalaki et al, 2003;Valdés-Galicia et al, 2005), Halberg et al (2005) have look for periods in the range of 0.8-2 years. Studying sudden cardiac death in Tbilisi, Republic of Georgia and Hong Kong, Halberg et al (2005) found periods of 0.988 and 0.843 years.…”

Section: Cardiovascular Systemmentioning

confidence: 99%

“…Mavromichalaki et al, 2003;Valdés-Galicia et al, 2005), Halberg et al (2005) have look for periods in the range of 0.8-2 years. Studying sudden cardiac death in Tbilisi, Republic of Georgia and Hong Kong, Halberg et al (2005) found periods of 0.988 and 0.843 years. Recently, Stoupel et al (2007b) reported a study performed in Baku, Azerbaijan, in order to explore the interaction of monthly geomagnetic activity levels and cosmic rays upon the monthly number of acute myocardial infarctions in two population groups, patients and fatal pre-admissions, occurring between 2003 and 2005; they found that both groups were inversely linked to geomagnetic activity and directly related to cosmic rays.…”

Section: Cardiovascular Systemmentioning

confidence: 99%