Incidence of stroke in relation to cognitive function and dementia in the Kungsholmen Project

Abstract

Mild dementia and cognitive impairment are associated with an increased incidence of stroke among subjects age 75 years old and over. Because stroke increases risk of dementia and prior stroke increases risk of a subsequent stroke, mild dementia and cognitive impairment may be a manifestation of clinically unrecognized stroke.

The Time Onset of Post Stroke Dementia

“…The most important demographic predictors of dementia after stroke, in sufficiently powered studies, are increasing age and low education level, but not gender, when the analysis is adjusted for age (Zhu et al, 2000).…”

“…The risk of dementia after stroke is higher in patients who were already dependent before stroke (Zhu et al, 2000). Pre-stroke cognitive decline without dementia, assessed by standardized questionnaires, is obviously associated with a higher risk of dementia after stroke (Zhu et al, 2000;Snowdon et al, 1997).…”

“…Pre-stroke cognitive decline without dementia, assessed by standardized questionnaires, is obviously associated with a higher risk of dementia after stroke (Zhu et al, 2000;Snowdon et al, 1997).…”

“…(Zhu et al, 2000). Arterial hypertension, a risk factor for VaD and AD, has not been clearly identified as a risk factor for PSD.…”

“…Arterial hypertension, a risk factor for VaD and AD, has not been clearly identified as a risk factor for PSD. Epileptic seizures (Esiri et al, 1999), sepsis, cardiac arrhythmias and congestive heart failure are independently associated with an increased risk of dementia after stroke (Zhu et al, 2000). However, the statistical relationship found between these disorders and dementia does not mean a causal relationship: it is also possible that dementia increases the risk of such events (Zhu et al, 2000).…”