Incidence of Side-Effects of Ticlopidine After Sirolimus-Eluting Stent Implantation Retrospective Analysis From Three Hospitals

Assessment of Sirolimus-Eluting Coronary Stent Implantation With Aspirin Plus Low Dose Ticlopidine Administration One Year Results From CYPHER Stent Japan Post-Marketing Surveillance Registry (J-PMS)

“…21 These observations suggest that the antiplatelet effect of ticlopidine 200 mg/day was sufficient to prevent thrombotic events in Japan with lower side effect rate of ticlopidine. 22,23 A benefit of this study is the limited case selection bias because no other DESs were available during the study period in Japan. On the contrary, there were several Japanspecific risk factors such as small reference vessel diameter (the average was 2.47 mm), high percent of diabetics (43.3%) and off-label use (68.3%), including 11.2% total occlusion.…”

Bare Metal Stent Restenosis Is Benign Clinical Entity in Japanese Patients

“…All patients received aspirin 100 mg daily indefinitely. Ticlopidine (100 mg twice daily) 13) or clopidogrel (50 or 75 mg daily) 14) was used for at least one month. Other medications were prescribed at the discretion of the referring physicians.…”

Acyclovir Induced Acute Kidney Injury In Acute Meningitis Patient: A Case Report Highlights the Concurrence Of AKI Risk Factors And The Neutropenic Effect Of Ticlopidine

“…The use of ticlopidine antiplatelet was reduced in the last decade due to its side effects such as neutropenia, thrombotic thrombocytopenic purpurea and liver toxicity [21][22][23][24][25]. In some cases, the occurrence of neutropenia can appear after eight weeks from initiation [25,26].…”

“…In some cases, the occurrence of neutropenia can appear after eight weeks from initiation [25,26]. It was reported that the neutropenic effect of ticlopidine had led to fatal outcome in patients with infectious diseases [27,28].…”