Incidence of Rotaviral Gastroenteritis at a Referral Centre in Saudi Arabia

Mn, Al-Ahdal; Sm, Qadri; Al‐Dayel, Fouad; Gy, Khan; Ba, Cunha

doi:10.5144/0256-4947.1991.19

Cited by 5 publications

(7 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, al-Bwardy et al [1988] reported rotavirus as a major cause of gastroenteritis in children in Riyadh with a prevalence of 44.3%. While Al-Ahdal et al [1991] reported 31.6%. In general the prevalence of rotavirus-positive stools from children with diarrhea ranges from 30% to 50% [Staat et al, 2002].…”

Section: Discussionmentioning

confidence: 94%

Enteric viruses in pediatric diarrhea in Saudi Arabia

Tayeb

Cruz

Al‐Qahtani

et al. 2008

Journal of Medical Virology

Self Cite

View full text Add to dashboard Cite

Between September 1st, 2002 and August 31st, 2003, a panel of 1,000 stool samples was collected from patients presenting with diarrhea in the three major urban centers of Saudi Arabia; Riyadh, Mecca, and Jeddah. Each sample was tested for rotavirus, and astrovirus by ELISA, G and P type was determined for all rotaviruses. Adenoviruses were sought by hexon-specific PCR and identified by RFLP. A subset of 253 samples was also tested for norovirus by ELISA. Data were analyzed for seasonality of infection, patient nationality and likelihood of hospitalization. Although the overall incidence of rotavirus identification in acute diarrheal stool continued to decline, this was still the virus identified most commonly (6%). Norovirus accounted for 3.5%, astrovirus, 1.9% and adenovirus, 1.4%. Type G9 rotavirus was found to be present (and already common) in 2003, predating its first reported identification in the country in 2004. Most of the virus infections (and most of the G9 detections) occurred in April, the month following the occurrence of the Hajj in the study year. Although most viruses were spread equally in the population, rotaviruses were significantly more common in non-Saudis than in Saudi citizens. Overall the data are consistent with an increase in all virus infections following al Hajj and the potential introduction of novel strains (such as the G9 rotaviruses) by pilgrims. Hospitalization was significantly associated only with norovirus infections.

show abstract

Section: Discussionmentioning

confidence: 94%

Enteric viruses in pediatric diarrhea in Saudi Arabia

Tayeb

Cruz

Al‐Qahtani

et al. 2008

Journal of Medical Virology

Self Cite

View full text Add to dashboard Cite

show abstract

“…32 Finally, another article studied the viral contamination of environmental surfaces on general paediatric wards and playrooms in major referral centres in Riyadh. 25 In all, these studies were from six different cities in the Kingdom of Saudi Arabia, namely Jeddah, 20 , 22 , 28 , 30 , 37 , 51 Taif, 21 , 28 Riyadh, 23 , 31 – 35 , 42 Jizan, 24 Dammam, 26 – 27 , 36 and Makkah. 29 These studies were conducted in hospitals ( Table 1 ) in the four major regions of Saudi Arabia ( Table 2 , Figure 1 ).…”

Section: Resultsmentioning

confidence: 99%

“…As shown in Table 1 , study duration was highly variable, ranging from a few weeks 26 , 27 to several years. 23 Two studies lasted less than a month, and eight others lasted a year or longer. The median study duration was 12.0 months.…”

Section: Resultsmentioning

confidence: 99%

Rotavirus infection in Saudi Arabia

2006

Annals of Saudi Medicine

View full text Add to dashboard Cite

BACKGROUNDHuman rotavirus, an important causative agent of severe gastroenteritis in infants and young children worldwide, leads to high morbidity in both developing and developed countries, including Saudi Arabia, and high mortality in developing countries. Effective control depends upon an accurate understanding of disease burden and the relative importance of circulating serotypes.METHODSWe examined the epidemiology and disease burden of rotavirus in Saudi Arabia through a review of 22 published studies of rotavirus and the aetiology of diarrhoea carried out from 1982 to 2003.RESULTSThe prevalence of rotavirus infection ranged between 10% to 46% with a median of 30%. Most cases were among children less than 2 years of age, and particularly in the first year of life. There were significant differences in seasonality within Saudi Arabia, with increased infection during winter in some cities and during summer in others. G1 was the predominant serotype followed by G4, G3 and G2, in 4 studies where strains had been G-typed. The prevalence of nontypeable strains ranged from 11.0% to 31.3%. No data were available on P types. Results of electropherotyping in 4 studies revealed that the long electropherotype was predominant.CONCLUSIONRotavirus is an important cause of severe diarrhoea in Saudi children. However, the available data on rotavirus strains in circulation are limited and there is an urgent need for up-to-date and comprehensive studies to evaluate rotavirus strains in circulation and identify unusual types that could be incorporated into future vaccines.

show abstract

“… Circulation of rotavirus within the country between 1988 to 2008 . RV reported in a high prevalence of diarrhoea cases overall in KSA during 1988 to 2001 [ 6 , 7 , 11 , 12 ]. Recent studies (after 2001) suggest that the incidence may be falling [ 8 , 10 , 13 ].The decrease in the incidence of rotavirus explained by improvements in public health introduced in recent years.…”

Section: Discussionmentioning

confidence: 99%

Increased prevalence of rotavirus among children associated gastroenteritis in Riyadh Saudi Arabia

Tayeb

Balkhy

Aljuhani

et al. 2011

Virol J

View full text Add to dashboard Cite

The aim of this study is to assess the epidemiology along with the molecular structure of rotavirus causing pediatric diarrhea among Saudi patients. However, in this report we sited the epidemiological reflect coming from our project.MethodsOne thousand and seven diarrheal stool samples had been collected between Jan1st, 2008 and OCT 31st, 2010 from hospitalized patients below the age of 5 year. Samples were then examined using Enzyme-linked immunosorbent assay (ELISA). Demographic data were collected including age, sex, date of admission and discharge. Finally, the chi-squire test, α level of significance was used to test the variables in the data.ResultsOf these 1007 stool samples, rotavirus was detected in 65.5% (660/1007 samples). We observed that children who are 1 year of age or less had more infection with rotavirus 81% (534/660) than those who is over 1 year of age (19%,126/660) (P = 0.000). Infections occur throughout the year with no clear significant seasonal peaks. The difference between males (57.5%, 380/660) and females (42.4%, 280/660) in terms of rotavirus positivity is statistically significant.ConclusionsThe high rate of positivity, are at variance with previously published reports of rotavirus infection in Saudi Arabia since 2005 which reported a major decrease year by year in the incidence of rotavirus over; 2005, 2006 and 2008 with percentage of; 25%, 10%, 6% respectively explained by improvements in public health introduced in recent years. Our increasing rate result (65.5%) may suggest emerging of unusual serotypes, not been represent to our country earlier.

show abstract

Incidence of Rotaviral Gastroenteritis at a Referral Centre in Saudi Arabia

Cited by 5 publications

References 18 publications

Enteric viruses in pediatric diarrhea in Saudi Arabia

Enteric viruses in pediatric diarrhea in Saudi Arabia

Rotavirus infection in Saudi Arabia

Increased prevalence of rotavirus among children associated gastroenteritis in Riyadh Saudi Arabia

Contact Info

Product

Resources

About