Incidence of psoriasis in Rochester, Minn, 1980-1983

Bell, L. M.

doi:10.1001/archderm.127.8.1184

Cited by 45 publications

(40 citation statements)

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“…Though it has been suggested that the ability of a primary care physician to diagnose skin complaints could be poor compared with a dermatologist, 27 psoriasis is one of the skin disorders best diagnosed by the GP according to results from a study in the United Kingdom. 27 In line with the study conducted in Rochester, Minnesota, 9 we found the incidence to slightly increase gradually with age up to the seventh decade of life in men and women. Our data also show, as suggested in some case series of psoriasis, a bimodal curve in the age distribution of the incidence of psoriasis.…”

Section: Commentsupporting

confidence: 84%

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Incidence and Risk Factors for Psoriasis in the General Population

Rivero²,

2007

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To study the clinical spectrum of psoriasis and the incidence in the general population and to identify risk factors associated with the occurrence of psoriasis.Design: Prospective cohort study with nested casecontrol analysis. Setting:The data source was the United Kingdom General Practice Research Database containing computerized clinical information entered by general practitioners (GPs). Patients:The study population comprised patients receiving a first-ever diagnosis of psoriasis between January 1, 1996, and December 31, 1997, and free of cancer.Interventions: Diagnosis of psoriasis was validated in a random sample of 14% of all ascertained cases requesting confirmation by the GPs. Nested case-control analysis included 3994 cases of psoriasis and a random sample of 10 000 controls frequency matched to cases by age, sex, and calendar year.Main Outcome Measures: Incidence rate of psoriasis and estimates of the odds ratio (OR) and 95% confi-dence interval (CI) for psoriasis as associated with selected risk factors. Results:The incidence rate of psoriasis was 14 per 10 000 person-years. Patients with antecedents of skin disorders and skin infection within the last year carried the highest risk of developing psoriasis (OR, 3.6 [95% CI, 3.2-4.1], and OR, 2.1 [95% CI, 1.8-2.4], respectively). Also, smoking was found to be an independent risk factors for psoriasis (OR, 1.4 [95% CI, 1.3-1.6]). We did not find an association between risk of psoriasis and antecedents of stress, diabetes, hypertension, hyperlipidemia, cardiovascular disease, or rheumatoid arthritis. Conclusions:The incidence rate in our study was higher than those published in other studies, probably owing to our case definition that considered cases recorded by the GPs independently of a specialist confirmation. Our results confirm the association between psoriasis, skin disorders, and smoking.

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Section: Commentsupporting

confidence: 84%

“…A study estimated an incidence rate of 60.4 per 100 000 person-years in a US general population. 9 Psoriasis is subject to flares and remissions and comes in many different variations and degrees of severity. It may be symptomatic throughout life and may be progressive with age or wax and wane in its severity.…”

mentioning

confidence: 99%

Incidence and Risk Factors for Psoriasis in the General Population

Rivero²,

2007

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“…This last study is subject to criticism because of the small number of patients and the fact that they were selected also in rheumatology departments. The recent data from the USA (14) are consistent with those of another population based study conducted in Olmsted County in the eighties, where a prevalence of 12.9% was found (2). A crucial point is how to judge isolated enthesitis.…”

Section: Prevalence Of Arthritis In Patients With Psoriasissupporting

confidence: 78%

“…This point is confirmed by the fact that, of the 1,844 medical records of patients with a diagnosis of psoriasis, only 1056 (57.3%) were confirmed by a dermatologist. Nethertheless, the incidence of psoriasis calculated from this study was 107.7/100.000 and therefore higher than that of the previous Rochester study (2). Two Nordic studies evaluating the incidence of inflammatory joint conditions also considered PsA.…”

Section: Incidencecontrasting

confidence: 57%

Epidemiology of Psoriasis and Psoriatic Arthritis

Cimmino¹

2011

Reumatismo

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“…Data from analytic epidemiologic studies (eg, case-control and nested cohort studies) with appropriate control for confounding variables have identified multiple risk factors: smoking, obesity, alcohol consumption, diet, infections, medications, and stressful life events. 1,3,[14][15][16][17][18][19][20] One of the largest studies investigating the association of smoking and obesity with psoriasis was the Nurses' Health Study II. This study, which included a cohort of over 78,000 nurses from the US, demonstrated a "dose-response" relationship for obesity and smoking on the risk of developing incident psoriasis.…”

Section: Risk Factorsmentioning

confidence: 99%

Psoriasis: epidemiology, natural history, and differential diagnosis

Basko-Plluska¹,

Petronic‐Rosic²

2012

PTT

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Psoriasis is a chronic, immune-mediated, inflammatory disease which affects primarily the skin and joints. It occurs worldwide, but its prevalence varies considerably between different regions of the world. Genetic susceptibility as well as environmental factors play an important role in determining the development and prognosis of psoriasis. Genomewide association studies have identified many genetic loci as potential psoriasis susceptibility regions, including PSORS1 through PSORS7. Histocompatibility antigen (HLA) studies have also identified several HLA antigens, with HLA-Cw6 being the most frequently associated antigen. Epidemiological studies identified several modifiable risk factors that may predispose individuals to developing psoriasis or exacerbate pre-existing disease. These include smoking, obesity, alcohol consumption, diet, infections, medications and stressful life events. The exact mechanism by which they trigger psoriasis remains to be elucidated; however, existing data suggest that they are linked through Th1-mediated immunological pathways. The natural history of psoriasis varies depending on the clinical subtype as well as special circumstances, including pregnancy and HIV infection. In general, psoriasis is a chronic disease with intermittent remissions and exacerbations. The differential diagnosis is vast and includes many other immunemediated, inflammatory disorders.

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Incidence of psoriasis in Rochester, Minn, 1980-1983

Cited by 45 publications

References 0 publications

Incidence and Risk Factors for Psoriasis in the General Population

Incidence and Risk Factors for Psoriasis in the General Population

Epidemiology of Psoriasis and Psoriatic Arthritis

Psoriasis: epidemiology, natural history, and differential diagnosis

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