Incidence of posterior reversible encephalopathy syndrome in eclamptic and patients with preeclampsia with neurologic symptoms

Mayama, Michinori; Uno, Kaname; Tano, Sho; Yoshihara, Masato; Ukai, Makoto; Kishigami, Yasuyuki; Ito, Yasuhiro; Oguchi, Hidenori

doi:10.1016/j.ajog.2016.02.039

Cited by 104 publications

(84 citation statements)

References 14 publications

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“…2,7,24,25 In the present study 3 (9.9%) patients with PRES had hemorrhagic complications. This finding is in consistent with study done Moyama et al 6 …”

Section: Figure 1: Persistent Symptomssupporting

confidence: 83%

“…Incidence of PRES in eclamptic women is 54.5% in the present study as compared to 62.5% in Nelli et al study, 19.2% in Mayama study. 14,6 In present study mean age of women diagnosed with PRES was 26±5.1 years and common in multigravidas. Manavi PJ study showed that average age of PRES is 21 years, many were primigravidas.…”

Section: Resultsmentioning

confidence: 99%

“…18 Recent study done by Mayama et al showed that patient who received antenatal steroid to enhance lung maturation or for treatment for HELLP revealed faster normalization of central nervous system function in eclamptic patients with PRES. 6,19 In the present study even though patients received corticosteroids for the treatment or to enhance the lung maturity effect on recovery is not studied.…”

Section: Figure 2a 2b 2c and 2d: Mri Images Of One Of The Patients mentioning

confidence: 99%

“…1,2,4 PRES can clinically are shared. 6 Neuroimaging is important for the diagnosis of PRES and radiological abnormalities are best demonstrated by magnetic resonance imaging. 1 Prompt recognition and treatment with the support of a multidisciplinary team are crucial to avoid the permanent neuronal damage and reduce the maternal mortality.…”

Section: Introductionmentioning

confidence: 99%

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Maternal and perinatal outcome in eclampsia complicated by posterior reversible encephalopathy syndrome; a three years’ experience in a tertiary care hospital

Karanth

Gonsalves

Sheela

et al. 2017

Int J Reprod Contracept Obstet Gynecol

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Background: PRES can be associated with number of medical conditions and was observed frequently in patients with preeclampsia and eclampsia. Neuroimaging is important for the diagnosis of PRES. Study was conducted to find out the maternal and perinatal outcome in patients with eclampsia complicated by posterior reversible encephalopathy syndrome (PRES).Methods: This is a retrospective study done at St. Johns Medical College Bangalore, between October 2013 and October 2016. We reviewed case records of all the patients with eclampsia who underwent neuro imaging studies and a diagnosis of PRES was made. The maternal and perinatal outcomes in these women were studiedResults: In the past three years we had 55 cases of eclampsia who underwent neuroimaging studies for persistent neurological symptoms after 24 hours of MgSO4 treatment. Of these women 30 were diagnosed to have PRES. In the present study PRES was common in multiparous women and more in patients with antepartum eclamptic women. Mean age at diagnosis of PRES was 26±5.1 years. Common presenting symptoms were headache (93.3%) and vomiting (53.3%). The mean SBP/DBP was 180/110 mmHg. All patients who had recurrent seizures were controlled with MgSO4 alone. 53.3% of our patients had eclampsia related complications and 36.7% required ICU care. There were 3 maternal deaths (10%). Perinatal mortality was 20%.Conclusions: Neuroimaging in eclamptic patients with persistent neurological symptoms could help in early diagnosis of PRES and multidisciplinary approach in management could contribute significantly in reducing the maternal mortality and morbidity.

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“…2,7,24,25 In the present study 3 (9.9%) patients with PRES had hemorrhagic complications. This finding is in consistent with study done Moyama et al 6 …”

Section: Figure 1: Persistent Symptomssupporting

confidence: 83%

Section: Resultsmentioning

confidence: 99%

Section: Figure 2a 2b 2c and 2d: Mri Images Of One Of The Patients mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Maternal and perinatal outcome in eclampsia complicated by posterior reversible encephalopathy syndrome; a three years’ experience in a tertiary care hospital

Karanth

Gonsalves

Sheela

et al. 2017

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

show abstract

“…[1] Moreover, in the authors' clinical experience and according to findings in recent reports, severe hypertension often precedes other cerebral manifestations such as blindness in pregnancy, stroke, altered mental state and the posterior reversible encephalopathy syndrome (PRES). [2][3][4][5][6] PRES and severe hypertension in pregnancy A known maternal cerebral complication of severe pre-eclampsia is PRES. [2] This syndrome is a clinico-neuroimaging entity and is hypothesised to be related to impaired cerebral blood flow autoregulation that leads to either over-or under-perfusion of the brain.…”

Section: In Practicementioning

confidence: 99%

Severe hypertension in pregnancy: Using dynamic checklists to save lives

Moodley

Ngene

2016

S Afr Med J

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Severe hypertension is a major cause of morbidity and mortality. The South African Saving Mothers report (2011 -2013) indicates that cerebral injury due to severe hypertension is resulting in avoid able maternal deaths. This demands that management of severe hypertension in pregnancy needs to be improved. A rapid-acting antihypertensive is recommended for the initial management of severe hypertension during pregnancy. A single dose of a rapid-acting agent may be ineffective, in which case incremental doses of the same medication or another antihypertensive may be required for adequate blood pressure control. To ensure that appropriate antihypertensives at the correct doses are administered, the use of a guideline in a dynamic checklist format is advocated and discussed in this article. It is envisaged that the use of dynamic checklists will be valuable to all healthcare professionals providing care during pregnancy and the puerperium.

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