Incidence of onychomycosis among psoriatic patients with nail involvement: a descriptive study

Rizzo, Daniele; Alaimo, R; Tilotta, Giovanna; Dinotta, Franco; Bongiorno, Maria Rita

doi:10.1111/myc.12042

Cited by 10 publications

(15 citation statements)

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“…According to our results, Greek nail psoriasis patients are more susceptible to onychomycosis than their healthy compatriots, as the thus far recorded prevalence of onychomycosis in Greece ranges from 15.72% to 20% Two studies, also examining small samples of only nail psoriasis patients found similar results . Few studies, also examining only nail psoriasis patients found a substantially higher prevalence of onychomycosis among them; it is possible that the inclusion of patients currently being or having recently been treated with immunosuppressive agents can justify the noted difference . The majority of studies examining psoriasis patients with as well as without psoriatic nail lesions have reported a smaller prevalence of onychomycosis than the one found in our study .…”

Section: Discussioncontrasting

confidence: 85%

Prevalence of onychomycosis among patients with nail psoriasis who are not receiving immunosuppressive agents: Results of a pilot study

Tsentemeidou

Vyzantiadis

Kyriakou

et al. 2017

Mycoses

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Nail psoriasis and onychomycosis can often be hard to differentiate clinically and may coexist, complicating each other's course. The aim of this study was to determine the prevalence of onychomycosis among patients with nail psoriasis not being treated with immunosuppressive agents, which constitute an independent risk factor for fungal infections. A cross-sectional study was performed. All adult patients with nail psoriasis who were not receiving antifungal and/or immunosuppressive treatment were recruited at the 2nd University Dermatology Department of Aristotle University of Thessaloniki from 10/2016 till 02/2017. If onychomycosis was clinically suspected, nail samples were collected and direct microscopy with 15% KOH solution and culture were performed. Target-NAPSI and DLQI score were also calculated. Of the 23 patients recruited, 20 were men and 3 were women, with a mean age of 53.43 years (48.25, 58.62), a mean target-NAPSI score of 10.72 (9.62, 11.77) and a mean DLQI score of 10.17 (7.46, 12.89). A total of 34.78% of patients tested positive for onychomycosis. Yeast were isolated in 37.50% of cases, non-dermatophyte filamentous fungi in 37.50% and T. rubrum in 12.50%. The prevalence of onychomycosis among nail psoriasis patients is higher than that among the general population of Greece (15%-20%). Yeast and moulds predominate in infection cases of nail psoriasis patients.

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Section: Discussioncontrasting

confidence: 85%

Prevalence of onychomycosis among patients with nail psoriasis who are not receiving immunosuppressive agents: Results of a pilot study

Tsentemeidou

Vyzantiadis

Kyriakou

et al. 2017

Mycoses

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“…found that nail psoriasis was more frequent in psoriatic patients with skin Koebner phenomenon than in patients without. Furthermore, NAPSI score of patients with nail psoriasis and onychomycosis was shown to be higher compared to patients without onychomycosis, although this difference was not statistical significant. In the publication by Zisova et al ., patients with nail infection due to Candida spp.…”

Section: Does Onychomycosis Act As Koebner Phenomenon and Exacerbatesmentioning

confidence: 80%

“…Some publications suggest that onychomycosis is more frequent in patients with nail psoriasis in comparison with patients without . However, other scientific papers did not prove a significant difference while others even found a lower incidence of onychomycosis in patients with nail psoriasis . Recently, Klaassen et al .…”

Section: Should We Distinguish the Two Diseases Or Should We Prove Thmentioning

confidence: 99%

“…Probably yes. The fungal nail infection could act as a type of Koebner phenomenon, leading to worsening or even triggering nail psoriasis . Ghosal et al .…”

Section: Does Onychomycosis Act As Koebner Phenomenon and Exacerbatesmentioning

confidence: 99%

“…5 It accounts for 50% of all nail disorders. 6 Prevalence in general population is very high and can reach up to 29.7%. 7 It affects more frequently male patients and its incidence is increasing with age.…”

Section: Onychomycosismentioning

confidence: 99%

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Onychomycosis in patients with nail psoriasis: a point to point discussion

Rigopoulos

Papanagiotou

Daniel

et al. 2016

Mycoses

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Onychomycosis is the most common nail disease and affects large parts of the population. Psoriasis is a frequently encountered skin disorder with nail involvement being found in up to 80% of the patients at some time of the course of the disease. It has been postulated that onychomycosis occurs more frequently in patients with nail psoriasis, but the results of studies in the literature are controversial. Moreover, onychomycosis could exacerbate psoriasis through Koebner phenomenon and the treatment of psoriasis could predispose to onychomycosis. Finally, the differential diagnosis could be a real challenge due to many same clinical signs, the high prevalence and the possible coexistence of the two diseases. This article attempts to enlighten all these different aspects of a very close relationship.

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