Incidence of Nonarteritic Anterior Ischemic Optic Neuropathy After Cataract Surgery: A Systematic Review and Meta-Analysis

Gupta, Arnav; Tejpal, Tushar; Ahmed, Iqbal Ike K.; Sharma, Rahul

doi:10.1097/wno.0000000000001888

Cited by 2 publications

(3 citation statements)

References 6 publications

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“…Moreover, a significant association with retrobulbar anesthesia administration has been noted; it has been postulated that the delayed hematoma expansion caused by the retrobulbar injection may play a role [77]. Delayed forms of perioperative NA-AION, occurring months after surgery, are supposed to be related to postoperative inflammation, and this hypothesis is supported by the evidence that these cases had a higher frequency of surgical complications, and are linked to prolonged surgical times and greater inflammation [78]. Finally, NA-AION cases have been described after uncomplicated intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents [79].…”

Section: Risk Factors and Associated Comorbiditiesmentioning

confidence: 99%

“…a. perioperative NA-AION associated with ocular surgery: several case reports of NA-AION presenting hours, days, or months (with a median latency of 6-12 weeks) after an uncomplicated cataract extraction, the so-called "postcataract extraction NA-AION", have been described [77,78]. Lam et al [77] calculated that patients developing a "post-cataract extraction NA-AION" have a 3.6 times higher risk of experiencing the same form in the fellow eye after the same procedure.…”

Section: Risk Factors and Associated Comorbiditiesmentioning

confidence: 99%

“…Lam et al [77] calculated that patients developing a "post-cataract extraction NA-AION" have a 3.6 times higher risk of experiencing the same form in the fellow eye after the same procedure. A recent review and meta-analysis found that the risk of NA-AION after cataract surgery is four times greater within the first year post-operatively and usually occurs within six months, with an incidence of <1 for 1000-3000 surgeries [78]. Although the pathogenesis of these cases is yet unclear, an acute intraoperative IOP spike abruptly reducing the OPP of the ONH in predisposing subjects seems to be the more likely mechanism.…”

Section: Risk Factors and Associated Comorbiditiesmentioning

confidence: 99%

See 2 more Smart Citations

Non-Arteritic Anterior Ischemic Optic Neuropathy (NA-AION): A Comprehensive Overview

Salvetat,

Pellegrini,

Spadea

et al. 2023

Vision

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Non-arteritic anterior ischemic optic neuropathy (NA-AION) represents one of the most important causes of blindness or severely impaired vision in middle-aged and elderly people. Unilateral optic disc edema and abrupt, painless vision loss are its defining features. It is commonly assumed that NA-AION is caused by an ischemic infarction of the optic nerve head, and, although the exact pathogenesis is still unknown, several risk factors and comorbidities associated with its development have been found. NA-AION occurs generally in patients older than 50 years who have small optic discs and vasculopathy risk factors. Even though numerous treatment options have been proposed, no available effective medical or surgical therapy or prophylactic measure for NA-AION currently exists. The purpose of present-day therapeutic strategies is therefore to identify and possibly control any underlying modifiable risk factors, aiming to prevent the development of new NA-AION episodes in the affected and fellow eye. A thorough assessment of NAION, including its history, epidemiology, etiology, pathophysiology, risk factors, associated comorbidities, clinical findings, diagnostic tests, treatment choices, prognosis, and future research, is the goal of this work.

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Section: Risk Factors and Associated Comorbiditiesmentioning

confidence: 99%