Incidence of Metabolic Syndrome in a Cohort of HIV-Infected Adults and Prevalence Relative to the US Population (National Health and Nutrition Examination Survey)

Abstract

Metabolic syndrome is mostly diagnosed through low HDL and high triglycerides in HIV. The risk of developing the syndrome is related to HIV, specific medications, and body fat.

Association of non-HDL cholesterol with subclinical atherosclerosis in HIV-positive patients

“…Nevertheless, the relative under-representation of MS in our rather young HIV+ cohort (41±9 years) compared to previous reports [51][52][53] was in agreement with epidemiological data obtained in a large French cohort, mostly HIV-negative, reporting MS (NCEP-ATP III criteria) in 10.2% of men with a mean age of 48 years, dropping to 5% for subjects younger than 40 years 54 . In the general population, MS is associated with inflammation and oxidative stress markers that contribute to the increased atherosclerosis risk 55,56 .…”

The feature of Metabolic Syndrome in HIV naive patients is not the same of those treated: Results from a prospective study

“…In the HIV-positive population, MS is considered an emerging risk factor for overall cardiovascular risk [1][2][3][4][5][6], though different populations and ethnic groups show prevalence ranging from 7 to 45.5% [7]. In the clinical setting, diagnosing MS is useful to identify and characterize HIV-infected patients at higher cardiovascular risk [8].…”

Metabolic abnormalities and overweight in HIV/AIDS persons-treated with antiretroviral therapy

“…Other investigations have shown that, apart from the undesirable antiretroviral side effects, HIV+ patients present a high rate of classical risk factors for the development of cardiovascular diseases and type 2 diabetes, such as inadequate eating habits, overweight, obesity, low level of physical activity and smoking 9,10 .…”