Incidence of Left Bundle Branch Block—Associated Cardiomyopathy

Barot, Harsh V.; Sharma, Sunita; Schwartzman, Andrew; Patten, Richard D.

doi:10.1016/j.cardfail.2017.07.155

Cited by 2 publications

(3 citation statements)

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“…z práce Barota je zřejmé, že k výraznému poklesu ejekční frakce v důsledku LBBB může dojít v dlouhodobém sledování až u 14 % pacientů s normální ejekční frakcí. 11 Experimentálně byla LBBB indukovaná kardiomyopatie prokázána i na zvířecím modelu. 12 Hisův svazek je možné stimulovat selektivně a neselektivně.…”

Section: Diskuseunclassified

(Super-responder to His-bundle pacing - case report)

Sussenbek¹,

Ionita²,

Rýzlová³

et al. 2020

Cor Vasa

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Prezentujeme případ 62letého pacienta s významně sníženou ejekční frakcí levé komory srdeční, u kterého byla indikována resynchronizační terapie pro srdeční selhání. Resynchronizace bylo dosaženo pomocí stimulace Hisova svazku. Po šesti týdnech od zákroku došlo u pacienta k vymizení symptomů srdečního selhání a značnému zlepšení echokardiografi ckých parametrů. Korekce blokády levého Tawarova raménka stimulací Hisova svazku u tohoto pacienta zásadně ovlivnila další průběh onemocnění.

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Section: Diskuseunclassified

(Super-responder to His-bundle pacing - case report)

Sussenbek¹,

Ionita²,

Rýzlová³

et al. 2020

Cor Vasa

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“…Out of the 157 potential references yielded by the electronic search, only nine articles met the inclusion criteria and formed the final dataset for analysis [5][6][7]22,[58][59][60][61][62]. Table 1 provides a summary of the characteristics of the included studies, which were recent, published between 2001 and 2019.…”

Section: Findings Study Characteristicsmentioning

confidence: 99%

“…Inclusion criteria varied slightly among individual studies. DCM patients with LBBB, severe HF (NYHA III-IV) [58]; ischemic CM with NYHA I-II, LVEF ≤ 30% and QRS ≥ 130 ms [22]; new onset NICM, LVEF ≤ 35% and LBBB or narrow (< 120 ms) QRS [6,7]; LVEF ≥ 45% without CAD [60]; LVEF ≤ 35%, LBBB and wide QRS ≥ 120 ms (no LBBB) [5]; and DCM with LVEG > 35% [62]. Despite these variations, Vaillant et al [59] provided a more comprehensive inclusion criterion that included almost all the diagnostic parameters in the individual studies.…”

Section: Diagnosismentioning

confidence: 99%

Left bundle branch block-induced cardiomyopathy: A review and pooled analysis of pathophysiology, diagnosis and clinical management

Albakri¹

2019

Intergr Clin Med

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The prevalence of left bundle branch block (LBBB) is significantly higher in the heart failure (HF) population compared to the general population. LBBB is more often associated with structural heart disease especially dilated cardiomyopathy (DCM) of a non-ischemic origin. In isolation, LBBB is not a cause of specific clinical concern and does not affect prognosis. However, in the presence of structural heart disease, LBBB is an independent predictor of cardiovascular mortality and HF events suggesting that long-standing LBBB may be the cause of HF. In addition, guideline directed medical treatment (GDMT) in DCM patients with LBBB is less effective or associated with worsening symptoms. Conversely, cardiac resynchronization therapy (CRT) has shown beneficial outcomes in DCM patients with LBBB. It reverses LV dysfunction and protects against HF events, which suggests the possibility of a specific type of LBBB-induced CM characterized by LV dilatation and depressed LV systolic function in the absence of any other known aetiology. Despite the evidence, current medical literature does not consider LBBB-induced CM as a clinical entity but a complication of CM or structural heart disease. Since LBBB-induced CM requires early treatment with CRT instead of after three months of GDMT, diagnosis of LBBB-induced CM is important to guide the choice of optimal treatment (CRT). The present review summarizes the current published evidence on LBBB-induced CM and identifies gaps in knowledge that may benefit from additional research.

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Incidence of Left Bundle Branch Block—Associated Cardiomyopathy

Cited by 2 publications

References 0 publications

(Super-responder to His-bundle pacing - case report)

(Super-responder to His-bundle pacing - case report)

Left bundle branch block-induced cardiomyopathy: A review and pooled analysis of pathophysiology, diagnosis and clinical management

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