Incidence of ischemic stroke post-chemotherapy: A retrospective review of 10,963 patients

Acute Ischemic Stroke Developing in the Course of Cisplatin Treatment of Small Cell Lung Cancer: A Case Report

“…[13] Her ne kadar ilk kemoterapiden sonra daha sık görülse de sisplatine bağlı iskemik inme kanser tipinden bağımsız olarak tedavi baş-langıcından sonraki ilk on gün içinde ortaya çıkabilir. [4] Sisplatine bağlı olarak ortaya çıkan iskemik inmenin altta yatan patogenezinde üç temel mekanizmanın rol oynadığı öne sürülmektedir: olarak gelişen hipomagnezeminin hiperkoagülabilite-yi indüklemesi. [12] Kanser hastalığının kendisi de tromboembolik olaylara sebep olabilmektedir.…”

Accident Vasculaire Cerebral Ischemique Post-Chimiotherapie Pour Cancer De La Langue Ischemic Stroke Induced by Chemotherapy for Tongue Cancer

“…On the other hand, it was difficult, if not impossible, to specify which of the two drugs was responsible the more so because the accident occurred at the end of the cure and the two drugs involved were already administered. In the study by Li et al [1], 62.5% of strokes occurred after cycle "1", suggesting a direct effect of chemotherapy. The free interval suggests an immunoallergic mechanism with a sensitization phase, whereas its absence suggests a direct toxic effect of drugs [6].…”

“…To our knowledge, only 19 cases were published between 1987 and 2015, 15 of these cases were men and 4 women, with an average age of 47.5 years [2]. In a retrospective study by Li et al Of 10,963 patients treated for various cancers, the incidence of stroke due to chemotherapy is less than 0.14%, and the frequency of complicated chemotherapy cycles by stroke is 0.035% [1]. It is a difficult diagnosis to be made, which can only be carried out in the absence of another cause of stroke, especially cardiac, and on chronological arguments: succession of events, interval with the administration drugs, and pharmacological arguments: known drug toxicity, possible drug combinations, and their biological effects.…”

“…Cerebral ischemic stroke is an unusual complication of chemotherapy, with an estimated frequency of 0.14% [1]. This is a serious event that changes the prognosis and quality of life of patients, and poses a real problem of care.…”

Ischemic stroke in a patient with cholangiocarcinoma: a case study

“…According to a retrospective study by Li et al 1 on 10,693 patients, 15 patients experiencing 16 ischemic strokes within the first month after the latest. Interesting, although the stroke is existed in cancerous patient, it is usually not considered in cancer therapy.…”