2005
DOI: 10.1086/430325
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Incidence of Herpes Zoster, Before and After Varicella‐Vaccination–Associated Decreases in the Incidence of Varicella, 1992–2002

Abstract: Our findings revealed that the vaccination-associated decrease in varicella disease did not result in an increase in the incidence of HZ. These early findings will have to be confirmed as the incidence of varicella disease continues to decrease.

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Cited by 252 publications
(176 citation statements)
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“…Studies of the impact of introduction of the varicella vaccine on zoster incidence have shown inconsistent findings. Jumaan et al [32] report no increase in zoster incidence between 1993 and 2002 among patients enrolled with a health insurance organization in Washington state [32]. In contrast, two further US studies report increases in zoster incidence rates following varicella vaccination.…”
Section: Temporal Changes In Incidencementioning
confidence: 97%
“…Studies of the impact of introduction of the varicella vaccine on zoster incidence have shown inconsistent findings. Jumaan et al [32] report no increase in zoster incidence between 1993 and 2002 among patients enrolled with a health insurance organization in Washington state [32]. In contrast, two further US studies report increases in zoster incidence rates following varicella vaccination.…”
Section: Temporal Changes In Incidencementioning
confidence: 97%
“…4,5 Among patients aged 20 to 59 years, there was an increase in the rate of HZ-related ED visits from 2006 to 2013, which may have been partially due to an elevated rate of ED visits for all indications in this age group. However, HZrelated ED visits represented an increasing percentage of all ED visits over this time period, which suggests a rising disease incidence in this age group.…”
Section: Discussionmentioning
confidence: 99%
“…The reason for this trend is currently unknown. [4][5][6] According to a hypothesis proposed by Hope-Simpson, exposure to primary varicella or subclinical latent varicella zoster virus can boost varicella zoster virus-specific immunity and reduce the risk of HZ. 7 A liveattenuated vaccine for varicella was introduced into the US vaccination schedule in 1995 for children aged 12 months or older, with subsequent significant declines in the incidence of varicella.…”
mentioning
confidence: 99%
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“…Ähnliche Beobachtungen liegen aus den USA vor [4,6,32]. In multivariaten Analysen ließ sich in den USA bislang kein Zusammenhang zwischen dem Anstieg der Zoster-Inzidenz und der Varizellenimpfung nachweisen [6], zumal der Herpes zoster durch zahlreiche Faktoren wie Alter, Geschlecht, Komorbidität und Weiteres deutlich beeinflusst wird.…”
Section: Diskussionunclassified