Incidence of HCV induced—Esophageal varices in Egypt

Abdel‐Aty, Mahmoud; Fouad, Mahmoud; Sallam, Mohammad M.; Elgohary, Elsayed A.; Ismael, Ali; Nawara, Abdallah; Hawary, Baha; Tag-Adeen, Mohammed; Salama, Khaled

doi:10.1097/md.0000000000005647

Cited by 13 publications

(7 citation statements)

References 21 publications

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“…In our study, there was no statistically significant difference between the two studied groups in baseline demographic and clinical characteristics which matches with previous studies comparing EUS-guided techniques versus conventional endoscopic technique 8 23 . The most common cause of portal hypertension in our study was chronic HCV-induced cirrhosis, this matches with data about prevalence of chronic HCV in Egyptian population; being the most common cause of portal hypertension 24 . As regards liver function assessment, our results found that most cases have CTP class A (83.7 %) and median MELD score nine which matches with the results published by Robles-Medranda et al which stated that median MELD score among 60 cases with GVs was 9.5 and CTP class A was the most common class 25 .…”

Section: Discussionsupporting

confidence: 92%

EUS-guided cyanoacrylate injection into the perforating vein versus direct endoscopic injection in the treatment of gastric varices

et al. 2022

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Background and aims: Endoscopic injection of gastric varices (GVs) using cyanoacrylate (CYA) is associated with significant adverse events. We aimed to compare the efficacy and safety of EUS-guided CYA injection into the perforating vein versus direct endoscopic injection (DEI) of CYA in treatment of high-risk GVs. Patients and methods: A randomized controlled trial that included 52 patients with high-risk GVs. Group A underwent EUS-guided injection into the perforator vein and Group B underwent DEI of 1 ml CYA. Endoscopic examination and doppler EUS were repeated after 3 months to confirm eradication. Obliteration by doppler EUS was considered by absence of doppler flow within the varix. Repeated injection was performed in the absence of obliteration. Doppler EUS examination was repeated at 3 and 6 months after each injection. Results: 43 patients including 27 males and 16 females with mean age 57 years completed the study. Variceal obliteration was achieved during the index session after 3 months in 8/21 (38.1%) in group B compared to 17/22 (77.2%) in group A (p=0.014). There was significant difference in the amount of CYA needed to achieve obliteration in group B compared to group A (2 vs.1 ml, p=0.027). There was no statistically significant difference in the overall adverse events rate between group A and group B (4.5% vs. 14.3%, p=0.345). Conclusion: EUS-guided CYA injection into the perforating veins achieved less amount of CYA, fewer number of sessions to obliteration, and similar overall adverse events rate in the treatment of high-risk GVs compared to DEI.

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Section: Discussionsupporting

confidence: 92%

EUS-guided cyanoacrylate injection into the perforating vein versus direct endoscopic injection in the treatment of gastric varices

et al. 2022

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“…In the previous study, upper GIT endoscopy findings were more frequent and less serious than colonoscopy findings and meanwhile colon cancer was the most common lesion in colonoscopy agreed with Abdel-Aty et al [23].…”

Section: Results Of Previous Studies Have Implicatedsupporting

confidence: 80%

Gastrointestinal Tract Endoscopic Evaluation of Iron Deficiency Anemia Patients without Gastrointestinal Manifestations Tanta University Hospitals Experience

Elmezayen

Hodeib

Enaba

et al. 2021

JAMMR

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Aims: Endoscopic evaluation of symptomless IDA patients and related lesions. Study Design: A Cross-sectional epidemiological study. Place and Duration of Study: The hematology unit of the Internal medicine department in Tanta university hospital, the duration of the study was 6 months from 1 January to 31 June 2019. Methodology: 100 consecutive patients with laboratory base diagnosis of IDA without GI symptoms were involved in the study and their clinical and biochemical variables were recorded. All patients underwent esophagogastroduodenoscopy (EGD) and colonoscopy. Endoscopic findings were documented as the presence/absence of bleeding-related lesions or other causes of IDA. Results: Possible cause of anemia was found in 95% and bleeding related lesions were found in 70% of patients. Upper GIT lesions were found in 70% of patients with 42% bleeding related lesions. Lower GIT lesions were found in 33% of patients with 21% bleeding related lesions. On multivariable logistic regression: old age, low hemoglobin (HB), low serum ferritin, and positive fecal occult blood test (FOBT) were predictive factors for GIT lesions and cause of IDA. Conclusion: Clinical and biochemical markers can predict GI lesions on endoscopy in IDA patients without GI symptoms. A high proportion of upper GI involvement makes EGD an initial endoscopic procedure however, a colonoscopy should be done in old age, and when upper GI lesions don't correlate with the severity of IDA.

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“…Several studies conducted globally on this topic have produced a wide range of results. The non-adherence rate in a global study conducted was 45% and a significant number of the hypertensive patients with co-morbidities were non-adherent to treatment [ 14 ]. The non-adherence rate from community-based studies in Bangladesh and Vietnam were as high as 85 and 49.8% respectively [ 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

Non-adherence to antihypertensive pharmacotherapy in Buea, Cameroon: a cross-sectional community-based study

Adidja

Agbor

Aminde

et al. 2018

BMC Cardiovasc Disord

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BackgroundHypertension is a challenging public health problem with a huge burden in the developing countries. Non-adherence to antihypertensive treatment is a big obstacle in blood pressure (BP) control and favours disease progression to complications. Our objectives were to determine the rate of non-adherence to antihypertensive pharmacotherapy, investigate factors associated with non-adherence, and to assess the association between non-adherence and BP control in the Buea Health District (BHD), Cameroon.MethodsA community-based cross-sectional study using stratified cluster sampling was conducted in the BHD from November 2013 – March 2014. Eligible consenting adult participants had their BP measured and classified using the Joint National Committee VII criteria. The Morisky medication adherence scale was used to assess adherence to BP lowering medication. Multivariable logistic regression models were used to predict non-adherence.ResultsOne hundred and eighty-three participants were recruited with mean age of 55.9 years. Overall, 67.7% (95% CI: 59.8–73.6%) of participants were non-adherent to their medications. After adjusting for age, sex and other covariates, forgetfulness (aOR = 7.9, 95%CI: 3.0–20.8), multiple daily doses (aOR = 2.5, 95%CI: 1.2–5.6), financial constraints (aOR = 2.8, 95%CI: 1.1–6.9) and adverse drug effects (aOR = 7.6, 95%CI: 1.7–33.0) independently predicted non-adherence to anti-hypertensive medication. BP was controlled in only 21.3% of participants and was better in those who were adherent to medication (47.5% versus 8.2%, p < 0.01).ConclusionAt least two of every three hypertensive patients in the Buea Health District are non-adherent to treatment. Forgetfulness, multiple daily doses of medication, financial constraints and medication adverse effects are the major predictors of non-adherence in hypertensive patients. These factors should be targeted to improve adherence and BP control, which will contribute to stem hypertension-related morbidity and mortality.

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Incidence of HCV induced—Esophageal varices in Egypt

Cited by 13 publications

References 21 publications

EUS-guided cyanoacrylate injection into the perforating vein versus direct endoscopic injection in the treatment of gastric varices

EUS-guided cyanoacrylate injection into the perforating vein versus direct endoscopic injection in the treatment of gastric varices

Gastrointestinal Tract Endoscopic Evaluation of Iron Deficiency Anemia Patients without Gastrointestinal Manifestations Tanta University Hospitals Experience

Non-adherence to antihypertensive pharmacotherapy in Buea, Cameroon: a cross-sectional community-based study

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