Incidence of Guillain-Barré syndrome among Zika virus infected cases: a report from Thailand

Joob, Beuy; Wiwanitkit, Viroj

doi:10.1590/0004-282x20170173

Cited by 4 publications

(1 citation statement)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…And yet, other similar reports have yielded contrasting results. For example, a recent report from Thailand, a country endemic for ZIKV, reported 1,417 cases of ZIKV infection but only two (0.14%) cases with concomitant GBS [21], a rate considerably lower than those previously observed in Polynesia and the Americas. In one early study of a ZIKV-infection outbreak in Yap (Micronesia), it was estimated that 73% of the population over three years of age had been infected (in a population of around 10,000 people), and no cases of GBS were reported [22].…”

Section: Discussionmentioning

confidence: 74%

Zika Virus infection and Guillain-Barré syndrome in Northeastern Mexico: A case-control study

et al. 2020

View full text Add to dashboard Cite

Background Beginning August 2017, we conducted a prospective case-control investigation in Monterrey, Mexico to assess the association between Zika virus (ZIKV) and Guillain-Barré syndrome (GBS). Methods For each of 50 GBS case-patients, we enrolled 2-3 afebrile controls (141 controls in total) matched by sex, age group, and presentation to same hospital within 7 days. Results PCR results for ZIKV in blood and/or urine were available on all subjects; serum ZIKV IgM antibody for 52% of case-patients and 80% of controls. Subjects were asked about antecedent illness in the two months prior to neurological onset (for case-patients) or interview (for controls). Laboratory evidence of ZIKV infection alone (PCR+ or IgM+) was not significantly different between case-patients and controls (OR: 1.26, 95% CI: 0.45-3.54) but antecedent symptomatic ZIKV infection [a typical ZIKV symptom (rash, joint pain, or conjunctivitis) plus

show abstract

Section: Discussionmentioning

confidence: 74%

Zika Virus infection and Guillain-Barré syndrome in Northeastern Mexico: A case-control study

et al. 2020

View full text Add to dashboard Cite

show abstract

Concurrent Guillain-Barré syndrome, transverse myelitis and encephalitis post-Zika and multiple arboviral immunity

Yasri¹,

Wiwanitkit

2019

Journal of the Neurological Sciences

View full text Add to dashboard Cite

Concurrent Guillain-Barré syndrome, transverse myelitis and encephalitis post-Zika: A case report and review of the pathogenic role of multiple arboviral immunity

Román

Anaya

Mancera-Páez

et al. 2019

Journal of the Neurological Sciences

View full text Add to dashboard Cite

We review post-infectious and post-vaccination neurological syndromes involving peripheral and central nervous system (CNS) and report an illustrative case of simultaneous occurrence of Guillain-Barré syndrome (GBS), confirmed by nerve conduction velocities, plus MRI-demonstrated transverse myelitis (TM) and acute encephalitis [acute disseminated encephalomyelitis] (ADEM+GBS) affecting a 24-year-old woman from Cúcuta, Colombia, who developed acute Zika virus (ZIKV) infection confirmed by serum reverse transcriptase-polymerase chain reaction (RT-PCR) and convalescent ZIKV IgG antibodies. With intensive care treatment, respiratory support, steroids, and intravenous immunoglobulin (IVIg), patient survived with residual flaccid paraparesis. She had preexisting immunity against Chikungunya virus (CHIKV) and Dengue virus (DENV) acquired before the arrival of ZIKV in Colombia. From reports in the Caribbean, Central and South America we review 19 cases of ZIKV-associated TM, encephalitis and ADEM occurring after a mean latent period of 10.5 days (range 1-96) post-infection. Although GBS and ADEM are usually considered post-infectious and associated with development of antibodies against peripheral nerve and CNS epitopes, we postulate that our case of ADEM+GBS is para-infectious, induced by acute ZIKV neurotropism boosted by active immunity against other arboviruses. Animal models of ZIKV demonstrated strong viral neurotropism enhanced by passive immunity with antibodies against arboviruses such as West Nile virus, CHIKV, or DENV. These considerations are relevant to prevent potential ZIKV vaccine-induced reactions involving central and peripheral nervous system.cycle where transmission to humans occurs mainly by female Aedes mosquitoes-also carriers of DENV and Chikungunya (CHIKV), an alphavirus of the family Togaviridae. In addition, sexual transmission of ZIKV has been demonstrated with virus isolations from urine, semen, blood, maternal milk and tears. Zika infection is manifested by fever, maculopapular rash, conjunctivitis and rare uveitis, arthralgias, muscle pain and headache, but about 80% of infections are asymptomatic [2]. Nonetheless, ZIKV is neuroinvasive and capable of causing numerous neurological manifestations [2].According to the World Health Organization (WHO) [3], a major

show abstract

Incidence of Guillain-Barré syndrome among Zika virus infected cases: a report from Thailand

Cited by 4 publications

References 2 publications

Zika Virus infection and Guillain-Barré syndrome in Northeastern Mexico: A case-control study

Zika Virus infection and Guillain-Barré syndrome in Northeastern Mexico: A case-control study

Concurrent Guillain-Barré syndrome, transverse myelitis and encephalitis post-Zika and multiple arboviral immunity

Concurrent Guillain-Barré syndrome, transverse myelitis and encephalitis post-Zika: A case report and review of the pathogenic role of multiple arboviral immunity

Contact Info

Product

Resources

About