“…Existing observations suggest that iron deficiency and its consequent anaemia may result in pathological changes in gastric mucosa including gastritis and gastric atrophy which in turn may lead to reduced secretion of gastric acid (Davidson and Markson, 1955; Badenoch, Evans and Richards, 1957) but Valberg, Taylor, Witts and Richards (1961) were unable to find any significant pathological change in gastric mucous membranes of iron deficient rats. The most striking reduction in gastric acid has been observed in those patients described as having idiopathic microcytic hypochromic anaemia with circulating antibodies to parietal cells (Shearman, Delamore and Gardner, 1966; Dagg, Goldberg, Anderson, Beck and Gray, 1964;MacFadyen, Goldberg, Dagg and Anderson, 1965). Patients with iron deficiency anaemia due to blood loss and without circulating antibodies to parietal cells have shown lesser degrees of hypochlorhydria (Shearman et al, 1966;Dagg et al, 1964).…”