Incidence of Fracture in Epileptics

Gender specific association of decreased bone mineral density in patients with epilepsy

“…Among them, epilepsy is a neurological condition of interest due to the presence of seizures that may cause increased frequency of bone fractures in up to 33.9% of epileptic individuals [19][20][21]. In 87 epileptic patients on phenytoin, the 7 years occurrence of non-seizure-related fractures was six times more frequent compared to normal population [22]. The peak period of all fractures in epileptic patients has been reported between 40 and 49 years of age [20].…”

Valgus intertrochanteric osteotomy in neglected simultaneous, bilateral, displaced subcapital femoral neck fractures in an epileptic pregnant woman

“…22 The increased fracture risk may be the result of increased risk of trauma from seizures seen in patients with epilepsy, 22 an increased load on the skeleton from muscle contractions during convulsions and decreased bone mineral density. The decreased bone mineral in the skeleton may be the result of antiepileptic medications (AED) having an influence on bone metabolism.…”

Bone mineral content in epileptics

“…The age was 61 _+ 12 ~ years and 57 -12 ~ years, respectively. The material has been described in detail by Lidgren and WallOe [8].…”

“…Others have demonstrated a low bone mineral content (BMC) in epileptics with and without biochemical blood changes [6,7]. In a group of epileptics, we have demonstrated six times the expected number of nonseizure related fractures [8]. The aim of the present study was to compare the bone mineral content and the muscle strength in this group of epileptics with those of a normal control group.…”