Incidence of Congenital Toxoplasmosis in Newborn Infant in the Western Amazon, Brazil

Abstract

Toxoplasmosis is a very common infection in our environment. The congenital form is the most worrisome, as it causes neurological and ocular lesions, leading to late sequelae, and may also cause abortions and death of the newborn. The objective of the study was to analyze the incidence of Congenital Toxoplasmosis in newborns in the State of Rondônia, Western Amazonia, in the period corresponding to 4 (four) years. The blood collection method was used on filter paper and the Elisa technique for the capture of Toxoplasmosis IgM. The results found in 102,963 newborns who underwent toxoplasmosis, 126 presented alterations. It is concluded that Congenital Toxoplasmosis in Rondônia is 1: 817 on newborns triates.

Toxoplasmosis infection in newborn: A systematic review and meta-analysis

“…Due to the fact that Amazon is a region with a hot and humid climate, the production of parasite eggs is higher, and therefore, the prevalence of toxoplasmosis infection in this region is higher in comparison to the other regions. [ 51 ]…”

“…In the study of Paraguassú-Chaves et al ., in 2019, the number of live births was 114,793, a total of 126 children out of 102,963 screened children with congenital toxoplasmosis were treated and followed up. [ 47 ]…”

“…(114,793). [ 47 ] The smallest sample size belonged to Marangoni ( n = 18), Paul ( n = 19), and Capobiango ( n = 31). In addition, the highest and lowest prevalence rates of T. gondii were observed in studies conducted by Paraguassú-Chaves et al .…”

“…In addition, the highest and lowest prevalence rates of T. gondii were observed in studies conducted by Paraguassú-Chaves et al . as 90% (95% CI: 90%–90%)[ 47 ] and Mehbod et al . as 6% (95% CI: 2%–9%).…”

Infecções Congênitas

“…Na disseminação congênita, ocorre a passagem de taquizoítas presentes, via circulação materno-fetal, em grande número, durante a fase aguda da infecção. Estudos demonstram que, no Brasil, há ampla variação regional de prevalência da Toxoplasmose congênita, ocorrendo uma média no país de taxas entre 3 e 20 casos por 10 mil nascidos vivos (ANDRADE & TONELLI, 2006;NETO et al, 2010;PARAGUASSÚ-CHAVES et al, 2019).…”