The aim of this study was to investigate whether the chronic obstructive pulmonary disease (COPD) assessment test (CAT) reflects the functional status of patients with COPD. Forty-seven patients underwent anthropometric assessment, spirometry, the 6-minute walk test (6MWT), the Glittre-activity of daily living (ADL) test (TGlittre), the London Chest ADL (LCADL) scale, and the CAT. The total score of the CAT correlated with 6MWT distance, TGlittre time spent, and LCADL %total (r ¼ À0.56, 0.52, and 0.78, respectively; p < 0.05 for all). There was significant difference in 6MWT distance (490 + 85.4 m vs. 387 + 56.8 m), TGlittre time spent (3.67 + 1.07 min vs. 5.03 + 1.32 min), and LCADL %total (24.2 + 3.02% vs. 44.4 + 13.3%) between the low and high impacts of COPD on health status (respectively, p < 0.05 for all) as well as in the LCADL %total between medium and high impact of COPD on health status (31.3 + 7.35% vs. 44.4 + 13.3%; p ¼ 0.001). In conclusion, the CAT reflects the functional status of patients with COPD.