Incidence of Childhood Cancer in Finland

Teppo, Lyly; Salonen, Tuula; Hakulinen, Timo

doi:10.1093/jnci/55.5.1065

Cited by 42 publications

(26 citation statements)

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“…The mean annual incidence of 25 per 106 children with newly diagnosed brain tumours is in agreement with incidence studies or cancer registry materials from the last 10 years (Doll et al, 1966;Cohen and Modan, 1968;Marsden and Steward, 1968;Bjelke, 1970;Doll et al, 1970;Percy et al, 1972;Stewart et al, 1973;Teppo et al, 1975;Young and Miller, 1975;Schoenberg et al, 1976;Heiskanen, 1977 material from the period in question (Doll et al, 1966;Doll et al, 1970;Teppo et al, 1975), the annual incidence rates in the present study are a little lower than in some other countries (Canada, Israel, New Zealand) but close to the rates for the other Scandinavian countries, England, Holland, Scotland, and the USA. Our study is retrospective, but the social system in Denmark ensures that sooner or later all children with symptoms of a brain tumour are admitted to hospital and reported to the Cancer Registry.…”

Section: Discussionsupporting

confidence: 81%

“…The few studies using the usual paediatric upper limit for childhood of 15 years of age also show varying age rates of incidence. Hendrick et al (1975) saw a sharp fall in incidence after the age of 10 years and Schoenberg et al (1976) found a peak incidence rate at 6'4 years, whereas Teppo et al (1975) and the present population study show no significant difference in age distribution from the child populations in Finland and Denmark respectively.…”

Section: Discussioncontrasting

confidence: 64%

“…Most reported series of brain tumours in children show an excess of boys (Weickmann, 1969;Koos and Ailler, 1971;Slooff and Slooff, 1975;Teppo et al, 1975;Yates and Becker, 1976). We saw only a slight and non-significant male excess especially in comparison with the child population of the years in question.…”

Section: Discussionmentioning

confidence: 99%

“…Such studies give a limited view of the epidemiological pattern of brain tumours in children (Schoenberg et al, 1976). Annual incidence rates between 1 0 and 5 0 x 105 for intracranial tumours in children less than 15 years of age have been reported in cancer registration from many countries (Doll et al, 1966;Bjelke, 1970;Doll et al, 1970;Teppo et al, 1975), while other epidemiological studies have shown an annual incidence rate of 2 0-2-6 intracranial tumours per 100,000 children in various regions or countries (Bergstrand et al, 1958;Marsden and Steward, 1968;Gjerris, 1976;Schoenberg et al, 1976).…”

mentioning

confidence: 99%

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Incidence and long term survival of children with intracranial tumours treated in Denmark 1935-1959

Gjerris¹,

Harmsen²,

Klinken³

et al. 1978

Br J Cancer

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Summary.-The total number of children under 15 years of age with intracranial tumours in Denmark during the years 1935-1959 was found to be 533. The average incidence was 21 new cases/106 children/year during the 25-year period in question, and 25/106 children/year during the first 17 years of Danish cancer registration. The sex ratio (290 boys to 243 girls) was not significantly different from that of the child population in Denmark. In 219 cases the tumour was located in the supratentorial and in 314 in the infratentorial space. 9300 of the tumours were histologically verified, with the following order of frequency for the most usual types: astrocytomas (all grades), medulloblastomas, ependymomas, and craniopharyngiomas. Follow-up was 1000%. For the 345 children who survived for more than one month after operation or diagnosis, 36% were alive after 15 years. 119 patients were alive in April 1974 and these were all observed between 15-40 years after diagnosis and operation. Of these 44 had tumours in the supratentorial and 75 in the infratentorial space. 660/" of the survivors with supratentorial and 9000 with infratentorial tumours led a normal life.Most of the survivors had had a cerebellar astrocytoma, a supratentorial astrocytoma, an apendymoma or oligodendroglioma, but other histological diagnoses were also represented, especially in the supratentorial group. The long-term prognosis was especially bad for children with brain-stem tumours, infratentorial ependymomas and medulloblastomas.

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Section: Discussionsupporting

confidence: 81%

Section: Discussioncontrasting

confidence: 64%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Incidence and long term survival of children with intracranial tumours treated in Denmark 1935-1959

Gjerris¹,

Harmsen²,

Klinken³

et al. 1978

Br J Cancer

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“…Reports from both Sweden (Ericsson et al,1.978) and Finland (Teppo et al, 1975) have demonstrated significant increases in the incidence of CNS tumours, and in Sweden the incidence of neuroblastoma and Wilms' tumour also rose during the period 1958-74. In neither of these studies was ascertainment estimated nor was the histology specially reviewed.…”

Section: Discussionmentioning

confidence: 96%

Incidence of malignant disease in childhood: a 24-year review of the Manchester Children's Tumour Registry data

Birch¹,

Marsden²,

Swindell³

1980

Br J Cancer

106

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The Manchester Children's Tumour Registry data for the period 1954-1977 have been analysed. The overall incidence of malignant disease in children aged 0-14 years in the north-west of England is estimated to be 100 per million person-years. The most common disease group is leukaemia, which forms about one third of the total number of cases. Among solid tumours, by far the most common presenting site is the central nervous system, representing nearly a quarter of all neoplasms. Wilms' tumour, neuroblastoma and soft-tissue sarcomas comprise approximately 5%, 6.5% and 6% respectively of the total. The tumours most frequently seen in adults (e.g. carcinoma of colon, lung and breast) are extremely rare in childhood. A significant excess of males was seen in acute lymphoid leukaemia, non-Hodgkin's lymphoma, Hodgkin's disease, medulloblastoma and hepatoblastoma. A female excess was found among germ-cell tumours. During the study period significant increases in incidence were seen among acute lymphoid leukaemia and epithelial tumours, and an increase in germ cell tumours approached significance.

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Childhood cancer in the denver metropolitan area 1976–1983

Savitz

Zuckerman

1987

Cancer

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Incidence rates for childhood cancers (ages 0-14 years) were produced for the Denver Standard Metropolitan Statistical Area for the period 1976-1983. Some unique features of the Denver area, especially the unusually high background levels of ionizing radiation, warrant comparisons with rates generated from other regions. A total of 348 childhood cancers were identifled in white (including Spanish surname) and black children, with the 200 cancers among males resulting in higher rates than for females (148 cases) for total cancers and selected major cancer types (leukemias, glii brain cancers, and non-Hodgkin's lymphomas). Compared with other geographic areas, Denver rates were very similar, with no marked excesses or deficits except for an increase in male endocrine cancers. Rates for Spanish surname children were very similar to the rates for other whites. Cancer 591539-1542,1987. HILDHOOD CANCERS are a diverse group of malig-C nant diseases which are grouped strictly by age of occurrence. Nonetheless, several lines of evidence justify viewing these cancers as an entity for etiologic studies. The common cancers of childhood (leukemias, lympho-mas, brain tumors, soft tissue sarcomas, and Wilms' tumor) are markedly different from those of adults (lung, colon, female breast, and prostate).' Secondly, the generally accepted temporal model for the etiology of adult cancers in which many years or even decades of exposure affect the incidence of neoplasms cannot be applicable to cancers which develop so early in life. Finally, most of the established exogenous determinants of adult cancers (tobacco use, sexual behavior, and occupational exposures) are not pertinent to cancers in children. Although childhood cancers are rare compared with adult cancers: they constitute one of the most important causes of death and serious morbidity in children, with a profound emotional impact on survivors and their families. Very little is currently known about the etiology of cancers in children3 justifying further descriptive analyses of cancer incidence in children. The current report s u p plements existing literature"8 with incidence data for childhood cancer in the Denver, Colorado area. Gold for their work in reviewing the diagnoses; the registrars at the hospital and state cancer registries for their cooperation; and Ms. Esther John for her work on the computer analysis.

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Incidence of Childhood Cancer in Finland

Cited by 42 publications

References 0 publications

Incidence and long term survival of children with intracranial tumours treated in Denmark 1935-1959

Incidence and long term survival of children with intracranial tumours treated in Denmark 1935-1959

Incidence of malignant disease in childhood: a 24-year review of the Manchester Children's Tumour Registry data

Childhood cancer in the denver metropolitan area 1976–1983

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