Incidence of Cardiovascular Complications and Nephropathy in Patients with Type 2 Diabetes in a Primary Care Setting in Riyadh, Saudi Arabia

Abstract

Background Diabetes mellitus is prevalent in Saudi Arabia. Our study aims to estimate the rate and time of developing macrovascular and microvascular complications in diabetic patients in a primary care setting. Methodology This is a retrospective cohort study. All collected data were retrieved using medical files and the electronic patient records of all diabetics having regular follow-ups in Family Medicine clinics, King Faisal Specialist Hospital & Research Centre in Riyadh, Saudi Arabia, from the beginning of January 2002 to the end of December 2018. The data included the demographics of patients diagnosed with diabetes mellitus, their HbA1c, and the follow-up duration of the development of complications, which included cardiovascular complications and diabetic nephropathy. Results We included 365 patients, of whom 47.1% males and 52.9% were females. The mean age of diabetes mellitus diagnosis in our population was 50 years (SD±11.3). The mean duration of follow-up was 7.14 years (SD±3.9). The rate of developing cardiovascular complications and diabetic nephropathy was 11.2% and 10.4%, respectively. The mean time to develop cardiovascular complications and diabetic nephropathy was 6 (SD±3.9) and 5.24 (SD±3.2) years, respectively. The mean time to develop the first diabetes complication was 5.5 years (SD±3.6). There was no statistical significance in the mean of HbA1c between patients who developed diabetic complications and those who did not. Conclusion Diabetes complications are common in the Saudi community. The duration of the development of cardiovascular complications and diabetic nephropathy was shorter than that indicated in international and national reports. Robust screening programs to diagnose and improve the control of diabetes mellitus should be established in the Kingdom.

Factors associated with glycemic control and diabetes complications in a group of Saudi patients with type 2 diabetes

“…[30,31] However, this was closer to that reported in Saudi Arabia (18.0%). [32] Differences between the Values are median and interquartile range. ACR = albumin creatinine ratio, BMI = body mass index, CVD = cardiovascular disease, HbA1c: = glycated hemoglobin, HDL-C = high density lipoprotein cholesterol, LDL-C = low density lipoprotein cholesterol, SBP = systolic blood pressure P value < .05 is considered significant.…”

“…[ 30 , 31 ] However, this was closer to that reported in Saudi Arabia (18.0%). [ 32 ] Differences between the studies could be related to potential genetic variability, subject selection, and the timing of CVD diagnosis. Cardiovascular events are more common in older adults, even in those without diabetes, which increases the risk of CVD.…”