Incidence of Atrial Fibrillation following Alcohol Septal Ablation for Hypertrophic Cardiomyopathy

Moss, Travis J.; Zipse, Matthew M.; Krantz, Mori J.; Sauer, William H.; Salcedo, Ernesto E.; Schuller, Joseph L.

doi:10.1111/anec.12335

Cited by 7 publications

(8 citation statements)

References 34 publications

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“…During 10‐year follow‐up, the cumulative risk of AF was at the level of 43% in patients with obstruction and 18% in those without . Another study in patients undergoing alcohol septal ablation (ASA) revealed that those who developed AF had significantly lower values of LVOT gradient after ASA ( P ≤ 0.005) . In a recent study, Lu et al found that significant left ventricular outflow gradient was related to a combined endpoint, a part of which was new onset AF .…”

Section: Discussionmentioning

confidence: 99%

Clinical and echocardiographic parameters as risk factors for atrial fibrillation in patients with hypertrophic cardiomyopathy

Kłopotowski

Kwapiszewska

Kukuła

et al. 2018

Clinical Cardiology

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Section: Discussionmentioning

confidence: 99%

Clinical and echocardiographic parameters as risk factors for atrial fibrillation in patients with hypertrophic cardiomyopathy

Kłopotowski

Kwapiszewska

Kukuła

et al. 2018

Clinical Cardiology

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“…Moss et al studied 132 patients with no history of AF. During follow up 10 patients (7.6%) developed AF with only two having permanent AF, those affected tended to be older but the NYHA class was the same as the AF free group 40 …”

Section: Complications Of Alcohol Septal Ablationmentioning

confidence: 94%

Alcohol septal ablation: A useful tool in our arsenal against hypertrophic obstructive cardiomyopathy

Savarimuthu

Harky

2020

J Card Surg

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Objective Affecting 1 in 500 individuals; hypertrophic cardiomyopathy is an autosomal dominant cardiovascular disorder which is prevalent throughout the world. Surgical myectomy (SM) and alcohol septal ablation (ASA) are two methods currently used for the management of drug refractory hypertrophic obstructive cardiomyopathy (HOCM). ASA may prove to be a useful, less invasive treatment in patients with HOCM Methods Electronic literature search was conducted to identify articles that discussed methods to treat drug refractory HOCM. No limits were placed on timing of the publication or the type of article. Keywords and MeSH terms were used and the results were summarized in the relevant section. Results Current evidence suggests that alcohol septal ablation is a safe and effective procedure in treating patients with HOCM with similar short‐ and long‐term outcomes when compared with SM. Conclusion ASA has been shown to be a safe and reliable procedure; imaging techniques and dedicated multi‐disciplinary teams can be used to select patients with HOCM. Though SM is recommended as gold standard treatment for drug refractory HOCM, ASA may play an increasing role in the near future due an ageing population; both ASA and SM can have a beneficial role in treating those who are affected by HOCM when the appropriate group of patients are selected for each intervention.

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“…Despite therapeutic anticoagulation, one patient developed stroke. [32] Follow up Long-term follow up is vital in order to ascertain the effects of ASA in patients with drug refractory HOCM. Usual methods include yearly echocardiograms looking into LVEF, septal wall thickness, valvular function, LV systolic and diastolic function.…”

Section: Complications Of Alcohol Septal Ablationmentioning

confidence: 99%

Alcohol Septal Ablation: A useful tool in our arsenal against hypertrophic obstructive cardiomyopathy

Savarimuthu

Harky

2020

Preprint

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Objective Affecting 1 in 500 individuals; Hypertrophic cardiomyopathy (HCM) is an autosomal dominant cardiovascular disorder which is prevalent throughout the world. Surgical myectomy and alcohol septal ablation (ASA) are two methods currently used for the management of drug refractory Hypertrophic obstructive cardiomyopathy (HOCM). ASA may prove to be a useful, less invasive tool when confronting patients with HOCM especially those who are more elderly or deemed to be a higher surgical risk. Methods Electronic literature search was conducted to identify relevant articles that discussed invasive methods to treat drug refractory HOCM. No limits were placed on timing of the publication or the type of article. Key words and MeSH terms were used to conduct the search and the results were summarized in the relevant section. Results Current evidence suggests that alcohol septal ablation is a safe and effective procedure in treating patients with HOCM with similar short-and long-term outcomes when compared with surgical myectomy. Selection of patient with appropriate assessment is the key for satisfactory outcomes. Conclusion ASA has been shown to be a safe and reliable procedure; advanced imaging techniques and dedicated multi-disciplinary teams can be used to carefully select patients with HOCM. Though surgical myectomy is recommended as gold standard treatment for drug refractory HOCM, however, ASA may play an increasing role in the near future due an ageing population; both ASA and SM can have a synergistic effect in treating those who are affected by HOCM.

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Incidence of Atrial Fibrillation following Alcohol Septal Ablation for Hypertrophic Cardiomyopathy

Abstract: Despite relieving LVOT obstruction and improving mitral regurgitation severity via ASA, new-onset AF remained a common complication of hypertrophic cardiomyopathy.

Cited by 7 publications

References 34 publications

Clinical and echocardiographic parameters as risk factors for atrial fibrillation in patients with hypertrophic cardiomyopathy

Clinical and echocardiographic parameters as risk factors for atrial fibrillation in patients with hypertrophic cardiomyopathy

Alcohol septal ablation: A useful tool in our arsenal against hypertrophic obstructive cardiomyopathy

Alcohol Septal Ablation: A useful tool in our arsenal against hypertrophic obstructive cardiomyopathy

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