Incidence of and Risk Factors for Alzheimer's Disease and Mild Cognitive Impairment in Korean Elderly

Abstract

Background/Aims: Knowledge of incidence rates and risk factors is essential for the development of strategies to treat patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI). Methods: A subpopulation of the Nationwide Survey on Dementia Epidemiology (460 Korean subjects aged ≥65 years from 2 rural and 2 urban districts) was followed up for 3.5 years. The age-specific incidence was estimated and risk factors were identified. Results: The age-standardized incidence of AD and MCI was 7.9 and 28.1 cases per 1,000 person-years, respectively. MCI was associated with a 6-fold increased risk of AD. Depression was a risk factor for AD with MCI. Age, lack of formal education, illiteracy, rural residence, and marital status were associated with the risk of AD. Conclusion: Strategies to control modifiable risk factors should be implemented to decrease the incidence of AD. © 2014 S. Karger AG, Basel

Testing Older Adults for Signs of Age-Related Cognitive Decline: Clock Drawing Test vs.Mini-Mental State Examination

“…Increased life expectancy does not associate with decreasing disabilities before death; despite the longer life, the older adults experience much disability until death that cause considerable suffering for them, their families, and incur huge socioeconomic costs to society (Sherwin, 2006). Therefore, prevention and treatment of cognitive impairment is important for aging population (Bae et al, 2015). In this regard, timely assessment and screening to identify older adults who are at risk of cognitive impairment seem necessary.…”

Rural–urban differences in the prevalence of cognitive impairment in independent community-dwelling elderly residents of Ojiya city, Niigata Prefecture, Japan

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Impaired Frontolimbic Connectivity and Depressive Symptoms in Patients with Alzheimer's Disease

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