Incidence, Mortality and Survival of Pediatric Cancer in Uruguay 2011-2015

Abstract

Introduction: Childhood cancer is a small proportion of all cancers but is still a major public health problem. Objective: To describe the 5-year incidence and mortality rates and net survival of childhood cancer in Uruguay. Method: Data on all malignant tumors diagnosed in children aged 0-14 were included for the period 2011-2015, obtained from the National Pediatric Registry of Cancer and from the Ministry of Health Mortality Registry, classified according to the International Classification of Childhood Cancer (ICCC-3). Information on the total population was obtained from national census records. Follow up was made until December 2020. Results: The standardized incidence rate was 128/million children per year. The distribution of the disease was similar to developed countries. The overall mortality rate was 28.2/million, with a net overall survival of 79.6% for the total population. Conclusion: Childhood cancer incidence in Uruguay is similar to developed countries. Progress in diagnosis and care have improved survival immensely, but efforts must continue to keep this trend and ameliorate the outcomes.

Advances in the Global Initiative for Childhood Cancer: implementation in Latin America and the Caribbean

“…Currently, several LAC countries have already reached the 2030 WHO target to have at least a 60% national survival rate among children and adolescents with cancer ( 4 , 10 ). Before the GICC, comprehensive national childhood cancer programs and strategies that included essential diagnostic and treatment services, universal health coverage, social protection, and research innovation had enabled improved outcomes in Argentina ( 10 ), Brazil ( 11 ), Chile ( 12 ), and Uruguay ( 13 ). Important advances in the promotion of “twinning” partnerships, in which hospitals in low- and middle-income countries form partnerships with hospitals in high-income countries, have proven to be immensely successful and effective in advancing pediatric oncology care in several other LMIC countries in the Region ( 14 ).…”

International Society of Paediatric Oncology (SIOP) Global Mapping Programme: Latin American Society of Pediatric Oncology (SLAOP) country‐level report

“…Overall, three registries reported national results. Peer‐reviewed results reported national 5‐year survival ranging from 51.7% for children (<15 years) in a cohort treated from 2009 to 2013 in selected areas in Colombia to a 5‐year survival of 70.6% reported in Uruguay in 2012, which improved to a 79.6% for the period 2011–2015 31–33 . Chile reported a 71.4% 5‐year survival in the period of 2007–2011 in a non‐peer‐reviewed official publication of the RENCI registry 19,20 .…”

“…Peer-reviewed results reported national 5year survival ranging from 51.7% for children (<15 years) in a cohort treated from 2009 to 2013 in selected areas in Colombia to a 5-year survival of 70.6% reported in Uruguay in 2012, which improved to a 79.6% for the period 2011-2015. [31][32][33] Chile reported a 71.4% 5-year survival in the period of 2007-2011 in a non-peer-reviewed official publication of the RENCI registry. 19,20 Peer-reviewed published results from Argentina at a national level showed 61.7% 5-year survival rate from 2000 to 2007, which improved to 72.2% in the period 2010-2014 as reported in a non-peer-reviewed official publication of the ROHA registry.…”