Incidence, mortality and survival in cancer of the cervix in Bangalore, India

Abstract

Cancer of the cervix is the most common cancer among women in India, constituting between one-sixth to one-half of all female cancers with an age-adjusted incidence rate ranging from 19.4 to 43.5 per 100,000 in the registries under the National Cancer Registry Programme (NCRP) (Annual Reports, NCRP, ICMR). It has been estimated that 100,000 new cases of cancer of the cervix occur in India every year, and 70% or more of these are Stage III or higher at diagnosis. However, the incidence of cancer of the cervix as suggested in this report appears to be on the decline in Bangalore. Besides incidence and clinical stage at presentation knowledge of survival is essential to complete the picture of establishing baseline indicators to monitor and evaluate cancer control programmes. Survival analysis was carried out in 2121 patients diagnosed during 1982-89 in the population of Bangalore, India. The observed 5 year survival was 34.4% and the relative survival 38.3%. Clinical stage at presentation was the single most important variable in predicting survival. The 5 year observed survival for stage I disease was 63.3%, for stage II 44.0%, for stage III 30.3% and for stage IV 5.7%.

Cancer patterns in eastern India: The first report of the Kolkata cancer registry

“…Cancer of the uterine cervix, which is still the leading female cancer in India with an estimated 126,000 new cases every year, is now showing a slow decline in incidence in urban populations. 31,32 The change in the lifestyles and habits of urban women could be responsible for the decline. However, the disease remains common among women in rural areas.…”

Improved survival in cervical cancer cases in a rural Indian population

“…Cervical Cancer is a major public health problem in the country as not only is the incidence high but most cases (70%) also present themselves in advanced stages of the disease, (Desai et al, 1989;Nandakumar et al, 1995). Interestingly, in the Rural Cancer Registry at Barshi, it was observed that, 3 years after its inception, there was a significant improvement in stages at diagnosis of cervical cancer (percentage of cases in stages I andII: 51% in 1990-92 vs 38% in 1988-89).…”

A comparative study of p53 expression in premalignant and malignant cervical lesions at a tertiary care institute of Rohilkhand region, India

“…[1] Unfortunately, over 70% of the cases of the cervical carcinoma present at a fairly advanced stage. [2] Current estimates indicate that, in India, every year approximately 1,23,000 women are diagnosed with cervical cancer, of which approximately 67,000 die from the disease. When comparing world cervical cancer crude incidence of 15.1, India has a higher crude incidence rate of 20.2 which is highest in Southern Asia.…”