Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the US Population, 2012

Rogers, Howard W.; Weinstock, Martin A.; Feldman, Steven R.; Coldiron, Brett M.

doi:10.1001/jamadermatol.2015.1187

Cited by 1,446 publications

(1,126 citation statements)

References 15 publications

(29 reference statements)

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“…NMSC, also referred to as keratinocyte carcinoma, of which BCC comprises more than half of all diagnoses, affects more than 3.3 million persons annually in the United States. 7 The treatment of BCC has long been a substantial component of the clinical practice of dermatologists, who are well versed in the numerous available therapeutic options. These clinical practice guidelines for the treatment of BCC provide evidence-based recommendations that offer clinicians a framework to manage patients with BCC.…”

Section: Introductionmentioning

confidence: 99%

Guidelines of care for the management of basal cell carcinoma

Baum¹,

Bordeaux²,

Brown³

et al. 2018

Journal of the American Academy of Dermatology

310

219

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Basal cell carcinoma (BCC) is the most common form of human cancer, with a continually increasing annual incidence in the United States. When diagnosed early, the majority of BCCs are readily treated with office-based therapy, which is highly curative. In these evidence-based guidelines of care, we provide recommendations for the management of patients with BCC, as well as an in-depth review of the best available literature in support of these recommendations. We discuss biopsy techniques for a clinically suspicious lesion and offer recommendations for the histopathologic interpretation of BCC. In the absence of a formal staging system, the best available stratification based on risk for recurrence is reviewed. With regard to treatment, we provide recommendations on treatment modalities along a broad therapeutic spectrum, ranging from topical agents and superficially destructive modalities to surgical techniques and systemic therapy. Finally, we review the available literature and provide recommendations on prevention and the most appropriate follow-up for patients in whom BCC has been diagnosed. ( J Am Acad Dermatol

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Section: Introductionmentioning

confidence: 99%

Guidelines of care for the management of basal cell carcinoma

Baum¹,

Bordeaux²,

Brown³

et al. 2018

Journal of the American Academy of Dermatology

310

219

View full text Add to dashboard Cite

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“…Nonmelanoma skin cancers (NMSCs), including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are the most common human cancer with more than five million cases treated every year [1]. Although they rarely metastasize, their management has become a real challenge to the health care system due to extensive treatment costs [2].…”

Section: Introductionmentioning

confidence: 99%

Photodynamic Therapy-Induced Microvascular Changes in a Nonmelanoma Skin Cancer Model Assessed by Photoacoustic Microscopy and Diffuse Correlation Spectroscopy

et al. 2016

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Abstract:One of the main mechanisms of action for photodynamic therapy (PDT) is the destruction of tumor vasculature. We observed the PDT-induced vasculature destruction in a mouse model of skin cancer using two techniques: Photoacoustic microscopy (PAM) and diffuse correlation spectroscopy (DCS). PAM showed high-resolution images of the abnormal microvasculature near the establishing tumor area at pre-PDT, as well as the subsequent destruction of those vessels post-PDT. DCS indicated a significant blood flow decrease after PDT, confirming the vascular destruction. Noninvasive assessment of vascular changes may be indicative of therapy response.

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“…El cáncer de piel no melanoma es la forma más frecuente de cáncer en Estados Unidos; su incidencia anual se estima entre 1,3 a 3,5 millones de casos (1,2). En Colombia se evidenció un aumento en su incidencia al pasar de 23 a 41 por 100 000 habitantes entre los años 2003 y 2007, esperando al 2020 una incidencia de alrededor de 102 por 100 000 habitantes si persiste esta tasa de crecimiento (3).…”

Section: Introductionunclassified

Anestesia loco regional más sedación con dexmedetomidina para cirugía de Mohs con reconstrucción

et al. 2018

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Comparte ResumenIntroducción: la cirugía micrográfica de Mohs se emplea para la escisión de tumores cutáneos malignos y frecuentemente es seguida de reconstrucción, prolongando el procedimiento y causando ansiedad y molestia al paciente. Esta cirugía se realiza con anestesia local y sedación complementaria. Dentro de los anestésicos intravenosos la dexmedetomidina es una excelente opción; sin embargo, se han reportado casos de bradicardia severa asociado a inestabilidad hemodinámica y riesgo de complicaciones con su uso. Objetivo: describir la frecuencia de bradicardia con repercusión hemodinámica en pacientes llevados a cirugía micrográfica de Mohs más reconstrucción, bajo anestesia loco regional y sedación con dexmedetomidina. Métodos: estudio observacional descriptivo retrospectivo de 30 pacientes llevados a cirugía de Mohs entre el 1 de noviembre 2012 a 30 de noviembre de 2013. Resultados: el 53,3 % eran mujeres, la edad promedio fue de 68,4 años, 21,4 % fueron clasificados como ASA I, 53,5 % ASA II y 25 % ASA III. El tiempo quirúrgico promedio fue de 184 ± 61 minutos y de anestesia con dexmedetomidina fue 196 ± 65,2 minutos. Solo un paciente requirió atropina durante la cirugía y ningún paciente requirió conversión a anestesia general. Conclusión: la dexmetomidina es una buena alternativa para proporcionar sedación en los pacientes llevados a cirugía de Mohs bajo anestesia loco-regional, debido a su baja incidencia de bradicardia con repercusión hemodinámica y ausencia de la necesidad de soporte ventilatorio.Palabras clave: Cirugía de Mohs; Bradicardia; Anestesia local; Dexmedetomidina; Sedación. AbstractIntroduction: Mohs micrographic surgery is used for the excision of malignant skin tumors and often is followed by reconstruction, prolonging the procedure, causing anxiety and discomfort to the patient. Mohs surgery is performed with local anesthesia and complementary sedation. Among the intravenous anesthetics, Dexmedetomidine is an excellent option; however, there have been reports of severe bradycardia associated with hemodynamic instability and risk of complications with its use. Objective: to describe the frequency of bradycardia with hemodynamic repercussion in patients undergoing Mohs micrographic surgery plus reconstruction, under loco

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Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the US Population, 2012

Cited by 1,446 publications

References 15 publications

Guidelines of care for the management of basal cell carcinoma

Guidelines of care for the management of basal cell carcinoma

Photodynamic Therapy-Induced Microvascular Changes in a Nonmelanoma Skin Cancer Model Assessed by Photoacoustic Microscopy and Diffuse Correlation Spectroscopy

Anestesia loco regional más sedación con dexmedetomidina para cirugía de Mohs con reconstrucción

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