Incidence de la COVID-19 sur les issues de grossesse: examen systématique et méta-analyse

Wei, Shu Qin; Bilodeau-Bertrand, Marianne; Liu, Shiliang; Auger, Nathalie

doi:10.1503/cmaj.202604-f

Cited by 1 publication

(1 citation statement)

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“…Pre-eclampsia and eclampsia cause 7–15% of maternal deaths [ 31 ]. A systematic review with metanalysis suggests that COVID-19 can be associated with an elevated risk of pre-eclampsia, premature birth, and other adverse outcomes during pregnancy [ 32 ]. Studies from the United States, the United Kingdom, India, and Mexico have shown an increase in maternal mortality because of the COVID-19 pandemic [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Excess maternal mortality in Brazil: Regional inequalities and trajectories during the COVID-19 epidemic

Orellana

Jacques²,

Leventhal³

et al. 2022

PLoS ONE

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Background The COVID-19 pandemic has exceeded 6 million known disease-related deaths and there is evidence of an increase in maternal deaths, especially in low- and middle-income countries. We aimed to estimate excess maternal deaths in Brazil and its macroregions as well as their trajectories in the first 15 months of the COVID-19 epidemic. Methods This study evaluated maternal deaths from the Mortality Information System of the Ministry of Health, with excess deaths being assessed between March 2020 and May 2021 by quasi-Poisson generalized additive models adjusted for overdispersion. Observed deaths were compared to deaths expected without the pandemic, accompanied by 95% confidence intervals according to region, age group, and trimester of occurrence. Analyses were conducted in R version 3.6.1 and RStudio version 1.2.1335. Results There were 3,291 notified maternal deaths during the study period, resulting in a 70% excess of deaths regardless of region, while in the North, Northeast, South and Southeast regions, excess deaths occurred regardless of age group. Excess deaths occurred in the March-May 2021 trimester regardless of region and age group. Excess deaths were observed in the Southeast region for the 25-36-year-old age group regardless of the trimester assessed, and in the North, Central-West and South regions, the only period in which excess deaths were not observed was September-November 2020. Excess deaths regardless of trimester were observed in the 37-49-year-old age group in the North region, and the South region displayed explosive behavior from March-May 2021, with a 375% excess of deaths. Conclusions Excess maternal deaths, with geographically heterogenous trajectories and consistently high patterns at the time of the epidemic’s greatest impact, reflect not only the previous effect of socioeconomic inequalities and of limited access to maternal health services, but most of all the precarious management of Brazil’s health crisis.

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Section: Discussionmentioning

confidence: 99%