Incidence, Clinical Profile and Prognosis of Patients With Myocardial Infarction With Non-Obstructive Coronary Arteries in the Real World

Pais, J Lopez; Izquierdo, Beatriz Plata; Gonzalez, V; Magana, J Gorriz; Caballero, R Mata; Pascual, Marı́a; Galán, David; Peredo, Carlos Gustavo Martínez; Awamleh, Paula; Martín, J.A. Portillo

doi:10.1016/s0735-1097(17)33531-3

Cited by 6 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In general terms, they tend to be younger patients, with fewer traditional risk factors, have a better prognosis and also have a probable trigger event behind the initiation of symptoms [14]. Also, psycho-emotional disorders could play a special role and may be an interesting medical target for both the prevention and the complete healing in some MINOCA patients [15].…”

Section: Introductionmentioning

confidence: 99%

Psycho-emotional disorders as incoming risk factors for myocardial infarction with non-obstructive coronary arteries

et al. 2018

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Psycho-emotional disorders as incoming risk factors for myocardial infarction with non-obstructive coronary arteries

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Несмотря на достаточно большое количество исследований, посвященных MINOCA, до настоящего времени дискутируются вопросы частоты развития острого ИМ у пациентов без обструкции КА, нет единого мнения о прогнозе и вариантах клинического течения заболевания. И именно вокруг этих двух групп пациентов (с обструкцией и без обструкции КА) ведутся активные дискуссии и споры в отношении проблемы выбора оптимальной тактики лечения (аорто-коронарное шунтирование (АКШ), чрескожное коронарное вмешательство (ЧКВ), консервативное ведение) и дальнейшего прогноза [6][7][8]. Указанные обстоятельства свидетельствуют об актуальности проблемы MINOCA.…”

Section: оригинальные статьи § введениеunclassified

Clinical and laboratory features of primary acute myocardial infarction in patients with obstructive and non-obstructive coronary atherosclerosis

et al. 2019

View full text Add to dashboard Cite

According to the literature, 40-60% of patients with acute myocardial infarction (AMI) have obstructive multivessel coronary artery disease (CA) and 8.8% of patients have non-obstructive CA lesions. And it is around these two groups of patients that there are active discussions and disputes regarding the choice of optimal treatment tactics and further prognosis. The aim of the study was to study clinical and laboratory features of development and course of primary AMI in patients with multi-and single-vessel obstructive lesion of the CA compared with patients with non-obstructive CA lesions. Methods. The study has included patients hospitalized "through the ambulance channel" in the Department of cardiac intensive care of municipal clinical hospital named after S. S. Yudin Moscow with a diagnosis “primary acute myocardial infarction”, ACS with and without ST segment elevation, unstable angina in 2015-2016. The diagnosis of acute myocardial infarction (AMI) was established at the hospital stage according to the criteria of the "Third universal definition of myocardial infarction" in 2012. The study included 1240 patients who underwent coronary angiography (CAG) no later than 12 hours from the time of admission. The first group (comparison group) consisted of patients with AMI and the first detected multivessel obstructive atherosclerotic lesion of CA (664 patients), the second (interest group) consisted of patients with AMI and non-obstructive atherosclerotic lesion of CA (96 patients) meeting the MINOCA criteria. The third group consisted of patients with single-vessel obstructive lesion and complete acute occlusion of the CA (272 patients). Patients with hemodynamically significant lesions of the left CA trunk were not included in the study. The clinical and laboratory features of the course of acute primary myocardial infarction in patients with obstructive and non-obstructive coronary atherosclerosis were studied. The generally accepted statistical processing methods were used. A year after discharge from the hospital, 727 patients (468 patients from the 1st group, 78 from the 2nd group, 181 from the 3rd group) were interviewed by means of a structured telephone survey about the course of the disease (collection of medical history). The median follow-up was 12 months. (interquartile range 11-13 months). The endpoints were: re-hospitalization for any reason, re-coronary event, death. The received answers are entered into questionnaires and statistically processed. Results and conclusions. In patients with AMI and non-obstructive atherosclerotic CA lesion, pain behind the sternum is observed one and a half times less often (54.2%) than in patients with obstructive CA lesion (MOAPCA 86.1%, OAPCA 89.7%) and the cardiac co duction system is almost three times more likely to be affected ( 30% versus 8.4% and 12%). Only 12.5% of patients in this group had an abnormal Q wave (Q – myocardial infarction) on the ECG, therefore, a smaller volume of myocardial damage and a lower level of troponin than in patients of groups 1 and 3. During the first year after the development of AMI, patients with obstructive coronary atherosclerosis did not experience repeated coronary events, there were no indications for conducting CAG, PCI or CABG, in contrast to patients with obstructive lesion of CA. For multivascular obstruction (group 1), PCI was performed in 9.6% of patients and 3.8% of CABG. PCI was performed in group 3 with obstructive single-vessel lesion of CA in 7.7% of patients. In patients with AMI and obstructive single-vessel atherosclerotic lesion of CA (group 3), two and a half times less often (9.1%) myocardial reperfusion injury is observed, while in patients with multivascular obstructive CA defeat, this syndrome was observed in 21.3%.

show abstract

“…Psychoemotional disorders and CAS are the common pathological causes of myocardial infarction with nonobstructive coronary arteries (MINOCA) [3]. Intervention for psycho-emotional disorders was shown to be the medical target for both prevention and recovery in some patients with MINOCA [4].…”

Section: Introductionmentioning

confidence: 99%

In-Hospital Cardiac Arrest after Emotional Stress in a Patient Hospitalized with Gastrointestinal Symptoms and Chronic Anxiety Disorder

Jiang

Fang

et al. 2021

CVIA

View full text Add to dashboard Cite

Background: We report an acute emotional stress–induced in-hospital cardiac arrest in a patient admitted with gastrointestinal symptoms after experiencing chronic anxiety disorder.Case Presentation: The patient was admitted to the Second Xiangya Hospital, Central South University, withgastrointestinal symptoms and chronic anxiety disorder, and experienced cardiac arrest during hospitalization after acute emotional stress. Malignant ventricular tachycardia and cardiogenic shock were evidenced in this patient afterthe acute emotional stress. Severe and extensive coronary spasm was confirmed by emergency coronary angiography, and coronary spasm was relieved by intracoronary injection of nitroglycerin. The patient recovered from myocardial infarction with nonobstructive coronary arteries. However, the patient developed acute kidney dysfunction and severe pulmonary infection and eventually died of respiratory circulatory failure on the ninth day after the successful rescue.Conclusions: Acute emotional stress on top of chronic anxiety disorder in patients hospitalized for noncardiovascularreasons might lead to the development of life-threatening cardiovascular diseases, including coronary artery spasmand myocardial infarction with nonobstructive coronary arteries. Psychological management is of importance to improvethe outcome of these patients.

show abstract

Incidence, Clinical Profile and Prognosis of Patients With Myocardial Infarction With Non-Obstructive Coronary Arteries in the Real World

Cited by 6 publications

References 0 publications

Psycho-emotional disorders as incoming risk factors for myocardial infarction with non-obstructive coronary arteries

Psycho-emotional disorders as incoming risk factors for myocardial infarction with non-obstructive coronary arteries

Clinical and laboratory features of primary acute myocardial infarction in patients with obstructive and non-obstructive coronary atherosclerosis

In-Hospital Cardiac Arrest after Emotional Stress in a Patient Hospitalized with Gastrointestinal Symptoms and Chronic Anxiety Disorder

Contact Info

Product

Resources

About