Incidence, Clinical Presentation and Location at Diagnosis of Pediatric Inflammatory Bowel Disease: A Prospective Population‐Based Study in Northern France (1988‐1999)

Auvin, Stéphane; Molinié, F.; Gower‐Rousseau, Corinne; Brazier, Franck; Merle, V.; Grandbastien, Bruno; Marti, Raymond; Lerebours, Éric; Dupas, Jean‐Louis; Colombel, Jean–Frédéric; Salomez, Jean‐Louis; Cortot, Antoine; Turck, Dominique

doi:10.1097/01.mpg.0000162479.74277.86

Cited by 206 publications

(158 citation statements)

References 18 publications

(56 reference statements)

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“…The incidence in CD rose from 1.5/10 5 to 8.4/10 5 (mainly in the age group of 10-15 years), while that of UC was relatively stable at approximately 1.8-1.9/10 5 , except for 1990-1992. One of the largest studies has been reported from Northern France [43] . In a prospective follow-up study, a total of 7066 patients were diagnosed, 509 (7.2%) of them were under the age of 17 years at the time of diagnosis.…”

Section: Most Of the Published Data Come From The Unitedmentioning

confidence: 99%

Recent trends in the epidemiology of inflammatory bowel diseases: Up or down

Lakatos¹

2006

WJG

381

231

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Inflammatory bowel disease (IBD) is traditionally considered to be common in the Western world, and its incidence has sharply increased since the early 1950s. In contrast, until the last decade, low prevalence and incidence rates have been reported from other parts of the world including Eastern Europe, South America, Asia and the Pacific region. Recent trends indicate a change in the epidemiology of IBD with previously low incidence areas now reporting a progressive rise in the incidence, while in West European and North American countries the figures have stabilized or slightly increased, with decreasing incidence rates for ulcerative colitis. Some of these changes may represent differences in diagnostic practices and increasing awareness of the disease. The quality of studies is also variable. Additional epidemiologic studies are needed to better define the burden of illness, explore the mechanism of association with environmental factors, and identify new risk factors.

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Section: Most Of the Published Data Come From The Unitedmentioning

confidence: 99%

Recent trends in the epidemiology of inflammatory bowel diseases: Up or down

Lakatos¹

2006

WJG

381

231

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“…A European study reported that in the entire IBD population (children and adults) the incidence of Crohn's disease (CD) increased significantly (+23%), while the incidence of ulcerative colitis (UC) decreased (-17%) [1] . One of the best North American studies reported the incidence of IBD in Wisconsin children to be 7.05 per 100 000, with the incidence for Crohn's disease being �� 4.56, more than twice the rate of ulcerative colitis (2.14).…”

Section: Introductionmentioning

confidence: 99%

Special issues in pediatric inflammatory bowel disease

Dubinsky¹

2007

WJG

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The incidence of pediatric inflammatory bowel disease (IBD) is rising and recent advances in diagnostics and therapeutics have improved the care provided to these children. There are distinguishing features worth noting between early onset and adult onset IBD. Physical and psychosocial development remains a critical target for the comprehensive management of pediatric IBD. Children are not just little adults and consideration must be given to the stages of development and how these stages impact disease presentation and management. The final stage will be the transition from pediatric care to that of adult oriented care and special consideration must be given to make this a successful process. This review highlights special considerations in the management of the child with IBD.

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“…Budući da podatci svjetske literature govore u prilog trendu porasta incidencije kroničnih upalnih bolesti crijeva u djece, prvenstveno na račun Crohnove bolesti, ne čudi činjenica da je najčešće proučavan parametar baš incidencija bolesti, (10,11,16,17,21,22,(37)(38)(39). Najviši porast ukupne incidencije zabilježen je u Španjolskoj -u posljednjih 30-ak godina čak šesnaesterostruk (21,39).…”

Section: Incidencijaunclassified

“…Najviši porast ukupne incidencije zabilježen je u Španjolskoj -u posljednjih 30-ak godina čak šesnaesterostruk (21,39). Iako je prema literaturi uglavnom zabilježen veći porast incidencije Crohnove bolesti (10,17,21,22,38,39), podatci nisu konzistentni; npr. Italija bilježi značajan porast ulceroznog kolitisa (11).…”

Section: Incidencijaunclassified

Uloga nacionalnog registra u zbrinjavanju djece oboljele od kroničnih upalnih bolesti crijeva

Ivković

Hojsak²,

Trbojević³

et al. 2015

Paediatr Croat

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Kroničnim upalnim bolestima crijeva u djece, za razliku od odraslih, svojstven je teži tijek i prošireniji oblik bolesti te negativan utjecaj na rast i razvoj. U posljednjih nekoliko desetljeća zamijećen je trend porasta incidencije kroničnih upalnih bolesti crijeva UVODKronične upalne bolesti crijeva zahvaćaju gastrointestinalni sustav, obilježene su relapsirajućim tijekom, a uključuju Crohnovu bolest, ulcerozni i nedeterminirani kolitis. Bolest koja počinje u dječjoj dobi u mnogočemu se razlikuje od one u odrasloj, ne samo time što je agresivnija pa zahvaća veći dio probavnog sustava u usporedbi s odraslim bolesnicima (1, 2, 3), nego i tijekom vremena mijenja fenotip iz blažeg u teži oblik (1). Samim tim liječenje djece se bitno razlikuje od liječenja odraslih bolesnika.Najznačajnija osobitost upalnih bolesti crijeva u dječjoj dobi je zaostatak u rastu i spolnom razvoju koji negativno utječe na psihosocijalni razvoj djece, a time i na kakvoću njihovih života (4).Zbog velike varijabilnosti i brojnih specifi čnosti same dječje populacije i širokog spektra obilježja bolesti, jedini način za dugoročno sustavno praćenje oboljele djece je putem registra oboljelih, kojima je osnovna zadaća sustavno i kontinuirano prikupljanje i pohranjivanje podataka o oboljelima, koji služe kao osnova za planiranje i provedbu daljnjih istraživanja, ali i kliničko praćenje bolesnika.Cilj nam je stoga ovim radom u početnom dijelu istaknuti osobitosti kroničnih upalnih bolesti crijeva u djece, a potom prikazati obilježja, uloge i ciljeve nacionalnih registara za djecu oboljelu od kroničnih upalnih bolesti crijeva, te posebno istaknuti kliničku, ali i znanstvenu važnost utemeljenja takvog registra u našoj državi. OSOBITOSTI KRONIČNIH UPALNIH BOLESTI CRIJEVA U DJECEDjeca oboljela od kroničnih upalnih bolesti crijeva najčešće imaju prošireniji i teži oblik bolesti te drukčiji klinički tijek u odnosu na odrasle (5). Budući da se otprilike 1/4 -1/3 svih bolesnika dijagnosticira u dječjoj i adolescentnoj dobi (6), upalne bolesti crijeva u djece veliki su problem na koji se pravodobnom i adekvatnom intervencijom može znatno utjecati. Iako se najčešće dijagnosticiraju u kasnom djetinjstvu i adolescenciji, mogu se pojaviti u bilo kojoj pedijatrijskoj dobi, uključujući i dojenačku (7). Tijekom posljednjih pedesetak godina u cijelom je svijetu zamijećen porast inci-

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Incidence, Clinical Presentation and Location at Diagnosis of Pediatric Inflammatory Bowel Disease: A Prospective Population‐Based Study in Northern France (1988‐1999)

Cited by 206 publications

References 18 publications

Recent trends in the epidemiology of inflammatory bowel diseases: Up or down

Recent trends in the epidemiology of inflammatory bowel diseases: Up or down

Special issues in pediatric inflammatory bowel disease

Uloga nacionalnog registra u zbrinjavanju djece oboljele od kroničnih upalnih bolesti crijeva

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